Development of Teat-Dipping Nanoemulsion Loaded with Curcumin for Prevention of Intramammary Infection and Treatment of Mastitis as an Immune Stimulant

Research Project

Project/Area Number	24K09263
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 42020:Veterinary medical science-related
Research Institution	Nagoya University
Principal Investigator	スリヤサタポーンウィタヤ名古屋大学, アジアサテライトキャンパス学院(農), 特任教授 (60969591)
Co-Investigator(Kenkyū-buntansha)	大蔵聡名古屋大学, 生命農学研究科, 教授 (20263163) 中村翔名古屋大学, アジアサテライトキャンパス学院(農), 特任准教授 (50829223)
Project Period (FY)	2024-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2024)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2026: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2025: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2024: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	Curcumin / mastitis / nanoemulsion
Outline of Research at the Start	1. formulation of Cur-NE and test for antimicrobial property in vitro. 2. Tests of in vitro immune function performance of milk white blood cells from the quarters after teat dipping with Cur-NE. 3. Evaluating the spontaneous cure and in vivo immune function of Cur-NE teat dipping quarter of mastitis.