3D Genome Architecture of Epithelial Plasticity Across Species

Research Project

Project/Area Number	24K09474
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 44020:Developmental biology-related
Research Institution	Kumamoto University
Principal Investigator	HUANG Ruby 熊本大学, 国際先端医学研究機構, 客員教授 (50867108)
Co-Investigator(Kenkyū-buntansha)	Sheng Guojun 熊本大学, 国際先端医学研究機構, 特別招聘教授 (20399439)
Project Period (FY)	2024-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2024)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2026: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2024: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords	3D genome architecture / EMT
Outline of Research at the Start	The originality and creativity of this proposal under these 4 aims is the selection of 4 diverse epithelial contexts across the animal species to elucidate the fundamental regulatory mechanisms of epithelial-ness at the 3D genome level.