Research on the role of eosinophil surface markers and its clinical application to evaluation of remission of severe asthma with nasal polyps

Research Project

Project/Area Number	24K11355
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 53030:Respiratory medicine-related
Research Institution	Kurume University
Principal Investigator	川山智隆久留米大学, 医学部, 教授 (80289389)
Project Period (FY)	2024-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2024)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2026: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	気管支ぜん息 / 好酸球 / サブセット
Outline of Research at the Start	鼻茸合併重症ぜん息患者を対象にした前向き臨床研究によってバイオ製剤介入によって臨床的寛解に達する要因の中で、バイオ製剤介入前あるいは介入前後の喀痰、末梢血または鼻茸中の好酸球表面抗原の早期変化がぜん息寛解に及ぼすのかを検証する。