Identification of early recurrence factors after resection of pancreatic and biliary tract cancer from gene search of abdominal lavage fluid and AI deep learning.

Research Project

Project/Area Number	24K11842
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 55020:Digestive surgery-related
Research Institution	Tohoku University
Principal Investigator	中川圭東北大学, 医学系研究科, 准教授 (20542294)
Co-Investigator(Kenkyū-buntansha)	伊関雅裕東北大学, 大学病院, 助教 (80793877)
Project Period (FY)	2024-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2024)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2026: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2025: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	腹腔洗浄液 / CY / AI
Outline of Research at the Start	腹腔洗浄細胞診検体のct-DNAとAIによる細胞核画像解析を組み合わせることで、画一的に術後早期再発症例を予測し、手術のタイミングを明確に判断する診断法の開発を行う。この診断法確立によって、侵襲の多い膵癌・胆道癌の手術適応が施設や前後の治療によらず明確にされることが期待される。