Decoding the complexity and natural variation of the mouse tissue glycoproteome

• Project/Area Number: 24K17793
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
• Research Institution: Nagoya University
• Principal Investigator: KAWAHARA Rebeca 名古屋大学, 糖鎖生命コア研究所, 特任准教授 (60982098)
• Project Period (FY): 2024-04-01 – 2026-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2025: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2024: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: Glycoproteomics / Mouse tissue / Glycans / Mass spectrometry / glycobiology

Outline of Research at the Start

This project aims to comprehensively map the protein glycosylation across mouse tissues and genders using integrated multi-omics approaches. This project will generate unique glycoproteome datasets to serve as a molecular reference map for the study of aberrant glycosylation in human pathology.