Identification and characterization of ubiquitously active cis-regulatory elements in mouse and their implications in tumor suppression

Research Project

Project/Area Number	24K18097
Research Category	Grant-in-Aid for Early-Career Scientists
Allocation Type	Multi-year Fund
Review Section	Basic Section 43060:System genome science-related
Research Institution	The University of Tokyo
Principal Investigator	Loza Lopez.Martin.de.Jesus 東京大学, 医科学研究所, 助教 (30963194)
Project Period (FY)	2024-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2024)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2026: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2024: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	Bioinformatics / Epigenetics
Outline of Research at the Start	Investigation of potential housekeeping tumor suppressor genes using multi-omics data from mouse samples. We expected to characterize potential tumor suppressor genes in mice for many kinds of cancers (pan-cancer) and their root pathways at different cancer stages.