Interplay between Aging and Tubulin Posttranslational Modifications

• Project/Area Number: 24K18114
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 44010:Cell biology-related
• Research Institution: Hiroshima University
• Principal Investigator: IJAZ FARYAL 広島大学, 医系科学研究科(医), 助教 (80845595)
• Project Period (FY): 2024-04-01 – 2027-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2026: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2025: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: Aging / Tubulin / PTMs

Outline of Research at the Start

Research on aging's molecular effects, especially on tubulin PTMs, is crucial due to global aging trends. Limited data exists on this intersection, mainly from studies on neurodegenerative diseases and cancer. Understanding this link can inform strategies for healthier aging and disease treatments.