Elucidating the role of innate immune-like lymphocytes in the pathogenesis of Kawasaki disease and Kawasaki disease coronary artery aneurysms

• Project/Area Number: 24K18896
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52050:Embryonic medicine and pediatrics-related
• Research Institution: Wakayama Medical University
• Principal Investigator: 鈴木 崇之 和歌山県立医科大学, 医学部, 助教 (40816691)
• Project Period (FY): 2024-04-01 – 2027-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2026: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2025: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2024: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 川崎病

Outline of Research at the Start

川崎病および川崎病冠動脈瘤発症における自然免疫様リンパ球の役割を明らかにすることで、疾患の病態理解の向上ならびに、川崎病冠動脈瘤発症リスクの高い患者を早期に抽出し、適切な介入を可能とすることを目指す。