Roles of immune cells derived from clonal hematopoiesis in B-cell lymphomas

• Project/Area Number: 24K19213
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 54010:Hematology and medical oncology-related
• Research Institution: University of Tsukuba
• Principal Investigator: NGUYEN THI・MINH・YEN 筑波大学, 附属病院, 研究員 (20968010)
• Project Period (FY): 2024-04-01 – 2027-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2026: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2025: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2024: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: B cell lymphoma / clonal hematopoiesis / immune cells

Outline of Research at the Start

We will investigate the significance of immune cells derived form TET2-mutated CH by using a mouse DLBCL model.