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膵頭十二指腸切除術後の脂質異常症の病態メカニズムの解明

Research Project

Project/Area Number 24K19360
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 55020:Digestive surgery-related
Research InstitutionKobe University

Principal Investigator

南野 佳英  神戸大学, 医学部附属病院, 特定助教 (70714666)

Project Period (FY) 2024-04-01 – 2026-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2025: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2024: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords膵頭十二指腸切除 / 脂質代謝 / 脂質異常症
Outline of Research at the Start

患者血漿を用いて脂質の輸送を担うリポタンパク質20画分の血中濃度をゲル濾過HPLC法にて定量する。術後の脂質吸収・代謝・輸送の継続的かつ網羅的な変化の詳細を解明し、さらに腫瘍再発や脂肪肝発症と関連する新たな脂質関連バイ オマーカーと新規治療戦略の探索を試みる。

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Published: 2024-04-05   Modified: 2024-06-24  

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