Cutting-edge bio-material for 3D printed bone fixation plates

• Project/Area Number: 24K20065
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 57070:Developmental dentistry-related
• Research Institution: Health Sciences University of Hokkaido
• Principal Investigator: ZunigaHeredia EnriqueEzra 北海道医療大学, 歯学部, 助教 (60978550)
• Project Period (FY): 2024-04-01 – 2029-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2028: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2027: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2026: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2025: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2024: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: 3D Printing / Orthognathic Surgery / Biodegradable Materials / Bioactive Glasses / Customized plates

Outline of Research at the Start

Developing a novel 3D-printable material by blending PLA, copolyesters, and functionalized bioactive glasses for orthognathic surgery, focusing on enhanced biodegradability, mechanical strength, and custom fit, tested through comprehensive in vitro and in vivo analyses for improved patient outcomes.