A One-Health metagenomic study of viruses at Indonesia's threatened human-nature interface

• Project/Area Number: 24K20193
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58020:Hygiene and public health-related: including laboratory approach
• Research Institution: Kyoto University
• Principal Investigator: オフィンニ ユディル 京都大学, 白眉センター, 特定助教 (30837901)
• Project Period (FY): 2024-04-01 – 2026-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2025: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2024: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: One Health / Metagenome / Viral infection / Zoonosis / Indonesia

Outline of Research at the Start

Viral spillover events are increasing in recent decades, caused by anthropogenic damage. Indonesia has the second most biodiversity globally, yet its ecological stability is threatened by intensifying human activities. The One Health approach is imperative to investigate and mitigate the risk of viral spillovers. Here, I aim to use the approach to study the breach of human-nature interface in the context of viral infections in Indonesia. This study may uncover zoo-/anthroponotic diseases and translate into real-world policy to mitigate environmental desecration and risk of future epidemics.