Study of the usefulness of preoperative inspiratory muscle training in esophageal cancer patients: Randomized controlled trial

• Project/Area Number: 24K20485
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59010:Rehabilitation science-related
• Research Institution: Kindai University
• Principal Investigator: 水澤 裕貴 近畿大学, 大学病院, 技師 (70900124)
• Project Period (FY): 2024-04-01 – 2029-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2028: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2027: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2026: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2025: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2024: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 術前吸気筋トレーニング

Outline of Research at the Start

本研究はランダム化比較試験である．対象は, 手術予定の術前化学療法を行う胸腹部食道癌患者である．対象者をIncentive Spirometry群(Control群)もしくはInspiratory Muscle Training(IMT群)をランダムに割り付ける. Incentive Spirometry群はコーチ2(smiths medical)を用いて、IMT群はPower breath(エントリージャパン社)を用いて、いずれも術前化学療法期間中に実施する．主要評価項目は, 術後呼吸器合併症発症率, 副次評価項目ついて，化学療法開始時，手術前, 術後1, 3ヶ月, 6ヶ月, 12ヶ月で評価測定を行う．