| Project/Area Number |
24K22054
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Review Section |
Medium-sized Section 49:Pathology, infection/immunology, and related fields
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| Research Institution | Osaka University |
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Principal Investigator |
ウィング ジェイムス 大阪大学, 感染症総合教育研究拠点, 准教授 (00648694)
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| Co-Investigator(Kenkyū-buntansha) |
坂口 志文 大阪大学, 免疫学フロンティア研究センター, 特任教授(常勤) (30280770)
松本 寿健 大阪大学, 医学部附属病院, 特任助教(常勤) (70644003)
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| Project Period (FY) |
2024-06-28 – 2026-03-31
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| Project Status |
Granted (Fiscal Year 2024)
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| Budget Amount *help |
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2025: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2024: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | Mass Cytometry / B-cells / Single cell analysis |
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| Outline of Research at the Start |
We will establish methodology for the multimodal assessment of antigen specific B and T-cell cells by the use of CyTOF and single cell RNA sequencing integrated with intracellular staining of phosphorylation markers. This will allow fine immunophenotyping and functional analysis of rare cells.
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