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Elucidation of EndMT induction of lymphatic endothelial cells

Research Project

Project/Area Number 24K22073
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 50:Oncology and related fields
Research InstitutionTokyo University of Science

Principal Investigator

昆 俊亮  東京理科大学, 研究推進機構生命医科学研究所, 准教授 (70506641)

Project Period (FY) 2024-06-28 – 2027-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2026: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2024: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsリンパ行性転移 / EndMT
Outline of Research at the Start

本課題では、リンパ管内皮細胞のEndMTを立脚点に、がん細胞のリンパ行性転移の実態に迫り、さらにはこの現象を制御する分子メカニズムを解明することを目的とする。そして将来的には、がん細胞のリンパ管侵襲を標的とした新たな制がん法の確立を目指す。

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Published: 2024-07-03   Modified: 2024-08-28  

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