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最小タンパク質の設計:最小ロスマンフォールドの探索と小型抗体への応用

Research Project

Project/Area Number 24KF0078
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeMulti-year Fund
Section外国
Review Section Basic Section 43040:Biophysics-related
Research InstitutionOkinawa Institute of Science and Technology Graduate University

Principal Investigator

LAURINO Paola  沖縄科学技術大学院大学, タンパク質工学・進化ユニット, 准教授 (90812256)

Co-Investigator(Kenkyū-buntansha) DUNKLEY ELSIE  沖縄科学技術大学院大学, タンパク質工学・進化ユニット, 外国人特別研究員
Project Period (FY) 2024-04-23 – 2026-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2025: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2024: ¥1,000,000 (Direct Cost: ¥1,000,000)
Outline of Research at the Start

We'll develop a bioinformatics pipeline for optimal sequences of minimal Rossmann Fold enzymes. We'll then clone, express, and purify the top 50 candidates, testing their binding activities for verification.

URL: 

Published: 2024-04-24   Modified: 2024-07-03  

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