| Project/Area Number |
24KF0263
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Multi-year Fund |
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| Section | 外国 |
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| Review Section |
Basic Section 46010:Neuroscience-general-related
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
合田 裕紀子 沖縄科学技術大学院大学, シナプス生物学ユニット, 教授 (40614897)
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| Co-Investigator(Kenkyū-buntansha) |
LU WEN-HSIN 沖縄科学技術大学院大学, シナプス生物学ユニット, 外国人特別研究員
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| Project Period (FY) |
2024-11-15 – 2027-03-31
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| Project Status |
Granted (Fiscal Year 2024)
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| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2026: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2025: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2024: ¥400,000 (Direct Cost: ¥400,000)
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| Outline of Research at the Start |
Astrocytes have many roles from providing structural and metabolic support to neurons to shaping synaptic connectivity and function with behavioral outcomes. However, characterization of astrocyte diversity and the underlying mechanisms of its generation has not been explored. Here we focus on hippocampus where astrocytes in different CA1 layers show distinct ability to modulate neuronal activity, to study the cell intrinsic and external basis for astrocyte diversity in CA1. We will identify the key regulators and reveal how astrocytic layers in CA1 are organized.
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