| Project/Area Number |
24KJ0689
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Multi-year Fund |
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| Section | 国内 |
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| Review Section |
Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
|
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| Research Institution | The University of Tokyo |
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Principal Investigator |
BEATTIE Adam Tianxing 東京大学, 大学院理学系研究科(理学部), 特別研究員(DC2)
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| Project Period (FY) |
2024-04-23 – 2026-03-31
|
| Project Status |
Granted (Fiscal Year 2024)
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| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2025: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2024: ¥800,000 (Direct Cost: ¥800,000)
|
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| Outline of Research at the Start |
Proteins are used as drugs or catalysts, but many are unstable. We will show how to improve protein stability. From a known protein, we will create a large number of variants containing unnatural amino acids, then identify the most stable variants that still possess their drug or catalytic activity.
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