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シナプスにおける逆行性シグナルが生後発達期の機能的神経回路形成に果たす役割の解明

Research Project

Project/Area Number 25000015
Research Category

Grant-in-Aid for Specially Promoted Research

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo

Principal Investigator

狩野 方伸  東京大学, 医学系研究科, 教授 (40185963)

Co-Investigator(Kenkyū-buntansha) 崎村 建司 (崎村 健司)  新潟大学, 脳研究所, 教授 (40162325)
少作 隆子  金沢大学, 保健学系, 教授 (60179025)
橋本 浩一  広島大学, 医歯薬保健学研究科, 教授 (00303272)
Project Period (FY) 2013 – 2018
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥553,020,000 (Direct Cost: ¥425,400,000、Indirect Cost: ¥127,620,000)
Fiscal Year 2017: ¥109,200,000 (Direct Cost: ¥84,000,000、Indirect Cost: ¥25,200,000)
Fiscal Year 2016: ¥95,160,000 (Direct Cost: ¥73,200,000、Indirect Cost: ¥21,960,000)
Fiscal Year 2015: ¥96,070,000 (Direct Cost: ¥73,900,000、Indirect Cost: ¥22,170,000)
Fiscal Year 2014: ¥128,440,000 (Direct Cost: ¥98,800,000、Indirect Cost: ¥29,640,000)
Fiscal Year 2013: ¥124,150,000 (Direct Cost: ¥95,500,000、Indirect Cost: ¥28,650,000)
Keywordsシナプス / シナプス刈り込み / 生後発達 / 神経回路 / 逆行性シグナル / 小脳 / 登上線維 / マウス
Outline of Annual Research Achievements

平成29年度の計画全体としては、ほぼ計画通り順調に達成したが、平成29年7月に入手する予定であった遺伝子改変マウスの作製が想定以上に遅れ、2カ月遅れて平成29年9月にようやく入手できた。直ちにこの遺伝子改変マウスを交配して目的とする分子(IGF-1受容体を介するシグナルを抑制すると考えられる分子)のプルキンエ細胞特異的ノックアウトマウスの作出を開始したが、想定以上にマウスの妊娠率や出産率が悪く、平成29年度に計画していたシナプス刈り込みの機能解析実験に必要なプルキンエ細胞特異的ノックアウトマウスの個体数を得るのが困難になった。そこで十分な数のマウスを得るために、交配用のマウスの個体数を増やし、当初計画より繁殖期間を4ヶ月延長する必要が生じた(平成30年5月末まで)。さらにその後、このノックアウトマウスの機能解析と研究成果の取りまとめを行って、当初計画を終了するために、平成31年度に研究費を繰り越した。まず、生後20日から30日の当該分子のプルキンエ細胞特異的ノックアウトマウスから小脳スライスを作製し、プルキンエ細胞からホールセル記録を行った。登上線維を刺激した際に発生するシナプス応答から、プルキンエ細胞にシナプス結合する登上線維の本数を求め、さらにシナプス応答の振幅、およびキネティクスを解析した。その結果、登上線維シナプス刈り込みが障害されていることを確認した。以上の電気生理学的計測を終了し、データの取りまとめを行った。

Assessment Rating
Verification Result (Rating)

A

Assessment Rating
Result (Rating)

A: Progress in the research is steadily towards the initial goal. Expected research results are expected.

Report

(12 results)
  • 2019 Research Progress Assessment (Verification Result) ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report   Abstract(Research Progress Assessment) ( PDF )   Research Progress Assessment (Result) ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report   Research Progress Assessment (Comments on the Site Visits) ( PDF )
  • 2013 Abstract ( PDF )   Comments on the Screening Results ( PDF )   Annual Research Report
  • Research Products

    (289 results)

All 2019 2018 2017 2016 2015 2014 2013

All Journal Article (102 results) (of which Int'l Joint Research: 28 results,  Peer Reviewed: 98 results,  Open Access: 66 results,  Acknowledgement Compliant: 19 results) Presentation (187 results) (of which Int'l Joint Research: 80 results,  Invited: 15 results)

  • [Journal Article] Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells2019

    • Author(s)
      Sakai Y, Kassai H, Nakayama H, Fukaya M, Maeda T, Nakao K, Hashimoto K, Sakagami H, Kano M, Aiba A.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 2799-2799

    • DOI

      10.1038/s41598-019-38730-4

    • URL

      https://localhost/en/publications/80628ac5-37cf-4c7a-926d-d87ef03fe227

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ectopic positioning of Bergmann glia and impaired cerebellar wiring in Mlc1-over-expressing mice2018

    • Author(s)
      Kikuchihara Saori、Sugio Shouta、Tanaka Kenji F.、Watanabe Takaki、Kano Masanobu、Yamazaki Yoshihiko、Watanabe Masahiko、Ikenaka Kazuhiro
    • Journal Title

      Journal of Neurochemistry

      Volume: 147 Issue: 3 Pages: 344

    • DOI

      10.1111/jnc.14486

    • URL

      https://pure.teikyo.jp/en/publications/c8a5e4d8-85a0-4ec2-bdca-d25c6e55a3a4

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output2018

    • Author(s)
      Hashimotodani Y, Karube F, Yanagawa Y, Fujiyama F, Kano M
    • Journal Title

      Cell Reports

      Volume: 25 Issue: 10 Pages: 2704

    • DOI

      10.1016/j.celrep.2018.11.016

    • URL

      https://pure.teikyo.jp/en/publications/2a68c5ca-2b91-4cc2-a439-0b76b4a2f581

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Monoacylglycerol lipase deficiency affects diet‐induced obesity, fat absorption, and feeding behavior in CB1 cannabinoid receptor-deficient mice2018

    • Author(s)
      Yoshida Kenji、Kita Yoshihiro、Tokuoka Suzumi M.、Hamano Fumie、Yamazaki Maya、Sakimura Kenji、Kano Masanobu、Shimizu Takao
    • Journal Title

      The FASEB Journal

      Volume: 33 Issue: 2 Pages: 2484-2497

    • DOI

      10.1096/fj.201801203r

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Control of excessive neural circuit excitability and prevention of epileptic seizures by endocannabinoid signaling2018

    • Author(s)
      Sugaya Yuki, Kano Masanobu
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 75 Issue: 15 Pages: 2793

    • DOI

      10.1007/s00018-018-2834-8

    • URL

      https://localhost/en/publications/af568fc2-a090-4099-90a9-95f622d08c7b

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple Phases of Climbing Fiber Synapse Elimination in the Developing Cerebellum2018

    • Author(s)
      Kano Masanobu、Watanabe Takaki、Uesaka Naofumi、Watanabe Masahiko
    • Journal Title

      The Cerebellum

      Volume: 17 Issue: 6 Pages: 722-734

    • DOI

      10.1007/s12311-018-0964-z

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Near-infrared deep brain stimulation via upconversion nanoparticle-mediated optogenetics.2018

    • Author(s)
      Chen S, Weitemier AZ, Zeng X, He L, Wang X, Tao Y, Huang AJY, Hashimotodani Y, Kano M, Iwasaki H, Parajuli LK, Okabe S, Teh DBL, All AH, Tsutsui-Kimura I, Tanaka KF, Liu X, McHugh TJ.
    • Journal Title

      Science

      Volume: 359 Issue: 6376 Pages: 679-684

    • DOI

      10.1126/science.aaq1144

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum2018

    • Author(s)
      Uesaka Naofumi、Abe Manabu、Konno Kohtarou、Yamazaki Maya、Sakoori Kazuto、Watanabe Takaki、Kao Tzu-Huei、Mikuni Takayasu、Watanabe Masahiko、Sakimura Kenji、Kano Masanobu
    • Journal Title

      Neuron

      Volume: 97 Issue: 4 Pages: 796

    • DOI

      10.1016/j.neuron.2018.01.018

    • URL

      https://localhost/en/publications/f50bed37-bc60-416c-8e11-4cfcf1a2b6f1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Presynaptic Mechanisms Mediating Retrograde Semaphorin Signals for Climbing Fiber Synapse Elimination During Postnatal Cerebellar Development2018

    • Author(s)
      Uesaka N, Kano M
    • Journal Title

      Cerebellum

      Volume: 17 Issue: 1 Pages: 17

    • DOI

      10.1007/s12311-017-0888-z

    • URL

      https://localhost/en/publications/6cee8e10-0b5b-45ef-942e-76788bd31226

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Type 1 metabotropic glutamate receptor and its signaling molecules as therapeutic targets for the treatment of cerebellar disorders2018

    • Author(s)
      Hirai H, Kano M.
    • Journal Title

      Curr Opin Pharmacol

      Volume: 38 Pages: 51

    • DOI

      10.1016/j.coph.2018.02.002

    • URL

      https://pure.teikyo.jp/en/publications/3a285463-6c9f-405f-9b5d-8bcb895f444b

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum.2018

    • Author(s)
      Tan GH, Liu YY, Wang L, Li K, Zhang ZQ, Li HF, Yang ZF, Li Y, Li D, Wu MY, Yu CL, Long JJ, Chen RC, Li LX, Yin LP, Liu JW, Cheng XW, Shen Q, Shu YS, Sakimura K, Liao LJ, Wu ZY, Xiong ZQ.
    • Journal Title

      Cell Res.

      Volume: 28 Issue: 1 Pages: 90-110

    • DOI

      10.1038/cr.2017.128

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] CDC42EP4, a perisynaptic scaffold protein in Bergmann glia, is required for glutamatergic tripartite synapse configuration.2018

    • Author(s)
      Ageta-Ishihara N, Konno K, Yamazaki M, Abe M, Sakimura K, Watanabe M, Kinoshita M.
    • Journal Title

      Neurochem Int

      Volume: S0197-0186 Issue: 17 Pages: 30442-4

    • DOI

      10.1016/j.neuint.2018.01.003

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Input-specific NMDAR-Dcpendent potentiation of dendritic GABAergic inhibition.2018

    • Author(s)
      Chiu CQ, Martenson JS, Yamazaki M, Natsume R, Sakimura K, Tomita S, Tavalin SJ, Higley MJ.
    • Journal Title

      Ncuron.

      Volume: 97 Issue: 2 Pages: 368-377

    • DOI

      10.1016/j.neuron.2017.12.032

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis2018

    • Author(s)
      Nagahashi Masayuki、Yamada Akimitsu、Katsuta Eriko、Aoyagi Tomoyoshi、Huang Wei-Ching、Terracina Krista P.、Hait Nitai C.、Allegood Jeremy C.、Tsuchida Junko、Yuza Kizuki、Nakajima Masato、Abe Manabu、Sakimura Kenji、Milstien Sheldon、Wakai Toshifumi、Spiegel Sarah、Takabe Kazuaki
    • Journal Title

      Cancer Research

      Volume: 78 Issue: 7 Pages: 1713-1725

    • DOI

      10.1158/0008-5472.can-17-1423

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7?Null Mouse Cornea2018

    • Author(s)
      Littlechild Stacy L.、Young Robert D.、Caterson Bruce、Yoshida Hideyuki、Yamazaki Maya、Sakimura Kenji、Quantock Andrew J.、Akama Tomoya O.
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 59 Issue: 3 Pages: 1641-1641

    • DOI

      10.1167/iovs.17-22716

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice2017

    • Author(s)
      Nakai N, Nagano M, Saitow F, Watanabe Y, Kawamura Y, Kawamoto A, Tamada K, Mizuma H, Onoe H, Watanabe Y, Monai H, Hirase H, Nakatani J, Inagaki H, Kawada T, Miyazaki T, Watanabe M, Sato Y, Okabe S, Kitamura K, Kano M, Hashimoto K, Suzuki H, Takumi T.
    • Journal Title

      Sci Adv.

      Volume: 3 Issue: 6

    • DOI

      10.1126/sciadv.1603001

    • URL

      https://pure.teikyo.jp/en/publications/8f75d48d-17c6-49da-9c30-7be6c8e7d108

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells2017

    • Author(s)
      Miyazaki T, Yamasaki M, Hashimoto K, Kohda K, Yuzaki M, Shimamoto K, Tanaka K, Kano M, Watanabe M.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 114 Issue: 28 Pages: 7438

    • DOI

      10.1073/pnas.1617330114

    • URL

      https://pure.teikyo.jp/en/publications/c25d18f5-49a3-45de-9d85-d01159c3a02e

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Alternative splicing in the C-terminal tail ofCa<sub>v</sub>2.1 is essential for preventing a neurological disease in mice2017

    • Author(s)
      Aikawa T, Watanabe T, Miyazaki T, Mikuni T, Wakamori M, Sakurai M, Aizawa H, Ishizu N, Watanabe M, Kano M, Mizusawa H, Watase K.
    • Journal Title

      Hum Mol Genet.

      Volume: 26 Issue: 16 Pages: 3094

    • DOI

      10.1093/hmg/ddx193

    • URL

      https://pure.teikyo.jp/en/publications/2615bf41-f44c-4d8c-a33c-bc49fd0a6d15

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum2017

    • Author(s)
      Choo M, Miyazaki T, Yamazaki M, Kawamura M, Nakazawa T, Zhang J, Tanimura A, Uesaka N, Watanabe M, Sakimura K, Kano M.
    • Journal Title

      Nat Commun.

      Volume: 8 Issue: 1 Pages: 195-195

    • DOI

      10.1038/s41467-017-00260-w

    • URL

      https://pure.teikyo.jp/en/publications/7fc1a2b8-139f-4a01-9ddc-a4698401eef4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Maturation of Cerebellar Purkinje Cell Population Activity during Postnatal Refinement of Climbing Fiber Network2017

    • Author(s)
      Good JM, Mahoney M, Miyazaki T, Tanaka KF, Sakimura K, Watanabe M, Kitamura K, Kano M.
    • Journal Title

      Cell Rep.

      Volume: 21 Issue: 8 Pages: 2066

    • DOI

      10.1016/j.celrep.2017.10.101

    • URL

      https://pure.teikyo.jp/en/publications/ab9f004b-e71d-4879-a8d4-6f2b187db3f5

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease2017

    • Author(s)
      Kano Masanobu、Watanabe Takaki
    • Journal Title

      F1000Research

      Volume: 6 Pages: 416-416

    • DOI

      10.12688/f1000research.10485.1

    • URL

      https://pure.teikyo.jp/en/publications/167cc260-963f-4c06-9829-20cbc37ecfd3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells2017

    • Author(s)
      Rubio Mar?a E.、Matsui Ko、Fukazawa Yugo、Kamasawa Naomi、Harada Harumi、Itakura Makoto、Moln?r Elek、Abe Manabu、Sakimura Kenji、Shigemoto Ryuichi
    • Journal Title

      Brain Structure and Function

      Volume: 222 Issue: 8 Pages: 3375-3393

    • DOI

      10.1007/s00429-017-1408-0

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg72017

    • Author(s)
      Koike Masato、Shibata Masahiro、Sunabori Takehiko、Yamaguchi Junji、Sakimura Kenji、Komatsu Masaaki、Tanaka Keiji、Uchiyama Yasuo
    • Journal Title

      The American Journal of Pathology

      Volume: 187 Issue: 7 Pages: 1586-1600

    • DOI

      10.1016/j.ajpath.2017.02.020

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis.2017

    • Author(s)
      Yamaguchi J, Suzuki C, Nanao T, Kakuta S, Ozawa K, Tanida I, Saitoh T, Sunabori T, Komatsu M, Tanaka K, Aoki S, Sakimura K, Uchiyama Y.
    • Journal Title

      Autophagy

      Volume: 17 Issue: 5 Pages: 1-14

    • DOI

      10.1080/15548627.2017.1314897

    • NAID

      120006881392

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Unconventional role of voltage-gated proton channels (VSOP/Hv1) in regulation of microglial ROS production2017

    • Author(s)
      Kawai Takafumi、Okochi Yoshifumi、Ozaki Tomohiko、Imura Yoshio、Koizumi Schuichi、Yamazaki Maya、Abe Manabu、Sakimura Kenji、Yamashita Toshihide、Okamura Yasushi
    • Journal Title

      Journal of Neurochemistry

      Volume: 142 Issue: 5 Pages: 686-699

    • DOI

      10.1111/jnc.14106

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN12017

    • Author(s)
      Mashud Rana、Nomachi Akira、Hayakawa Akihide、Kubouchi Koji、Danno Sally、Hirata Takako、Matsuo Kazuhiko、Nakayama Takashi、Satoh Ryosuke、Sugiura Reiko、Abe Manabu、Sakimura Kenji、Wakana Shigeharu、Ohsaki Hiroyuki、Kamoshida Shingo、Mukai Hideyuki
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 7663-7663

    • DOI

      10.1038/s41598-017-07936-9

    • NAID

      120006366660

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Drebrin E regulates neuroblast proliferation and chain migration in the adult brain.2017

    • Author(s)
      Kajita Y, Kojima N, Koganezawa N, Yamazaki H, Sakimura K, Shirao T.
    • Journal Title

      Eur J Neurosci

      Volume: 46(6) Issue: 6 Pages: 2214-2228

    • DOI

      10.1111/ejn.13668

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Netrin-1 Derived from the Ventricular Zone, but not the Floor Plate, Directs Hindbrain Commissural Axons to the Ventral Midline2017

    • Author(s)
      Yamauchi Kenta、Yamazaki Maya、Abe Manabu、Sakimura Kenji、Lickert Heiko、Kawasaki Takahiko、Murakami Fujio、Hirata Tatsumi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11992-11992

    • DOI

      10.1038/s41598-017-12269-8

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbpl haploinsufficiency.2017

    • Author(s)
      Miyamoto H, Shimohata A, Abe M, Abe T, Mazaki E, Amano K, Suzuki T, Tatsukawa T, Itohara S, Sakimura K, Yamakawa K.
    • Journal Title

      Hum Mol Genet.

      Volume: 26 Pages: 4961-4974

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling2017

    • Author(s)
      Hayakawa-Yano Yoshika、Suyama Satoshi、Nogami Masahiro、Yugami Masato、Koya Ikuko、Furukawa Takako、Zhou Li、Abe Manabu、Sakimura Kenji、Takebayashi Hirohide、Nakanishi Atsushi、Okano Hideyuki、Yano Masato
    • Journal Title

      Genes & Development

      Volume: 31 Issue: 18 Pages: 1910-1925

    • DOI

      10.1101/gad.300822.117

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chondroitin Sulfate Is Required for Onset and Offset of Critical Period Plasticity in Visual Cortex2017

    • Author(s)
      Hou X, Yoshioka N, Tsukano H, Sakai A, Miyata S, Watanabe Y, Yanagawa Y, Sakimura K, Takeuchi K, Kitagawa H, Hensch TK, Shibuki K, Igarashi M, Sugiyama S
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 12646-12646

    • DOI

      10.1038/s41598-017-04007-x

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mechanistic insight into the suppression of microglial ROS production by voltage-gated proton channels (VSOP/Hv1)2017

    • Author(s)
      Kawai Takafumi、Tatsumi Shoki、Kihara Shinji、Sakimura Kenji、Okamura Yasushi
    • Journal Title

      Channels (Austin)

      Volume: 12 Issue: 1 Pages: 1-8

    • DOI

      10.1080/19336950.2017.1385684

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity2017

    • Author(s)
      Honda Atsuko、Usui Hiroshi、Sakimura Kenji、Igarashi Michihiro
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 51 Pages: 20936-20946

    • DOI

      10.1074/jbc.m117.809541

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Orexin modulates behavioral fear expression through the locus coeruleus2017

    • Author(s)
      Soya Shingo、Takahashi Tohru M.、McHugh Thomas J.、Maejima Takashi、Herlitze Stefan、Abe Manabu、Sakimura Kenji、Sakurai Takeshi
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 1606-1606

    • DOI

      10.1038/s41467-017-01782-z

    • NAID

      120007128779

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] RNG105/Caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation2017

    • Author(s)
      Kei Nakayama, Rie Ohashi, Yo Shinoda, Maya Yamazaki, Manabu Abe, Akihiro Fujikawa, Shuji Shigenobu, Akira Futatsugi, Masaharu Noda, Katsuhiko Mikoshiba, Teiichi Furuichi, Kenji Sakimura, and Nobuyuki Shiina
    • Journal Title

      eLife

      Volume: 6 Pages: 1-32

    • DOI

      10.7554/elife.29677

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Protocadherin-αC2 is required for diffuse projections of serotonergic axons2017

    • Author(s)
      Katori Shota、Noguchi-Katori Yukiko、Okayama Atsushi、Kawamura Yoshimi、Luo Wenshu、Sakimura Kenji、Hirabayashi Takahiro、Iwasato Takuji、Yagi Takeshi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 15908-15908

    • DOI

      10.1038/s41598-017-16120-y

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Corrigendum: Conditional Knockout of Cav2.1 Disrupts the Accuracy of Spatial Recognition of CA1 Place Cells and Spatial/Contextual Recognition Behavior.2017

    • Author(s)
      Jung D, Hwang YJ, Ryu H, Kano M, Sakimura K, Cho J.
    • Journal Title

      Front Behav Neurosci.

      Volume: 11 Pages: 242-242

    • DOI

      10.3389/fnbeh.2017.00242

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Hypoxia-induced inhibition of the endocannabinoid system in glioblastoma dell.2017

    • Author(s)
      Sugimoto N, Ishibashi H, Nakamura H, Yachie A, Ohno-Shosaku Takako.
    • Journal Title

      Oncology Report

      Volume: 38(6) Pages: 3702-3708

    • DOI

      10.3892/or.2017.6048

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] YAP functions as a mechanotransducer in oligodendrocyte morphogenesis and maturation.2017

    • Author(s)
      Shimizu T, Osanai Y, Tanaka KF, Abe M, Natsume R, Sakimura K, Ikenaka K.
    • Journal Title

      Glia

      Volume: 65 Issue: 2 Pages: 360-374

    • DOI

      10.1002/glia.23096

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impaired auditory processing and altered structure of the endbulb of Held synapse in mice lacking the GluA3 subunit of AMPA receptors.2017

    • Author(s)
      Garcia-Hernandez S, Abe M, Sakimura K, Rubio ME.
    • Journal Title

      Hear Res.

      Volume: 344 Pages: 284-294

    • DOI

      10.1016/j.heares.2016.12.006

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice.2017

    • Author(s)
      Yoneda M, Sugimoto N, Katakura M, Matsuzaki K, Tanigami H, Yachie A, Ohno-Shosaku T, Shido O.
    • Journal Title

      J Nutr Biochem.

      Volume: 39 Pages: 110-116

    • DOI

      10.1016/j.jnutbio.2016.10.002

    • NAID

      120005895700

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] SCN5A(K817E), a novel Brugada syndrome-associated mutation that alters the activation gating of Na<sub>V</sub>1.5 channel2016

    • Author(s)
      Kinoshita K, Takahashi H, Hata Y, Nishide K, Kato M, Fujita H, Yoshida S, Murai K, Mizumaki K, Nishida K, Yamaguchi Y, Kano M, Tabata T, Nishida N
    • Journal Title

      Heart Rhythm

      Volume: 13 Issue: 5 Pages: 1113

    • DOI

      10.1016/j.hrthm.2016.01.008

    • URL

      https://pure.teikyo.jp/en/publications/b2caf4d3-ab67-4148-bf17-9ce77d5e2d03

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins2016

    • Author(s)
      Matsuda K, Budisantoso T, Mitakidis N, Sugaya Y, Miura E, Kakegawa W, Yamasaki M, Konno K, Uchigashima M, Abe M, Watanabe I, Kano M, Watanabe M, Sakimura K, Aricescu AR, Yuzaki M.
    • Journal Title

      Neuron

      Volume: 90 Issue: 4 Pages: 752

    • DOI

      10.1016/j.neuron.2016.04.001

    • URL

      https://localhost/en/publications/d8d05ba5-11eb-4f5d-8f67-0eb097d2e36e

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Ionic Basis for Membrane Potential Resonance in Neurons of the Inferior Olive2016

    • Author(s)
      Matsumoto-Makidono, Y., Nakayama, H., Yamasaki, M., Miyazaki, T., Kobayashi, K., Watanabe, M., Kano, M., Sakimura, K., Hashimoto, K.
    • Journal Title

      Cell Reports

      Volume: 16 Issue: 4 Pages: 994

    • DOI

      10.1016/j.celrep.2016.06.053

    • URL

      https://pure.teikyo.jp/en/publications/3ce87e4a-7df7-4d28-8c16-070ceff28970

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures2016

    • Author(s)
      Sugaya Y, Yamazaki M, Uchigashima M, Kobayashi K, Watanabe M, Sakimura K, Kano M
    • Journal Title

      Cell Rep

      Volume: 16 Issue: 5 Pages: 1405

    • DOI

      10.1016/j.celrep.2016.06.083

    • URL

      https://pure.teikyo.jp/en/publications/eec1bb4c-8a7f-435d-bcc6-ead92b18f9a5

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus2016

    • Author(s)
      Madoka Narushima, Motokazu Uchigashima, Yuki Yagasaki, Takeshi Harada, Yasuyuki Nagumo, Naofumi Uesaka, Kouichi Hashimoto, Atsu Aiba, Masahiko Watanabe, Mariko Miyata and Masanobu Kano
    • Journal Title

      Neuron

      Volume: 91 Issue: 5 Pages: 1097

    • DOI

      10.1016/j.neuron.2016.07.035

    • URL

      https://pure.teikyo.jp/en/publications/bf67227c-49b3-4c38-ae2c-6d003084e0f6

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spatiotemporal dynamics of lesion-induced axonal sprouting and its relation to functional architecture of the cerebellum2016

    • Author(s)
      Dhar M, Brenner JM, Sakimura K, Kano M, Nishiyama H.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 12938-12938

    • DOI

      10.1038/ncomms12938

    • URL

      https://pure.teikyo.jp/en/publications/652b867e-26d5-4f3f-8b3f-f92b46d2e1d4

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Inhibition promotes long-Term potentiation at cerebellar excitatory synapses2016

    • Author(s)
      Binda F, Dorgans K, Reibel S, Sakimura K, Kano M, Poulain B, Isope P
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1

    • DOI

      10.1038/srep33561

    • URL

      https://pure.teikyo.jp/en/publications/0e592e75-2832-4819-8aaf-c6a1411a8b1f

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Conditional knockout of Cav2.1 disrupts the accuracy of spatial recognition of CA1 place cells and spatial/contextual recognition behavior2016

    • Author(s)
      Jung D, Hwang YJ, Ryu H, Kano M, Sakimura K, Cho J.
    • Journal Title

      Front Behav Neurosci.

      Volume: 10 Issue: NOV Pages: 214-214

    • DOI

      10.3389/fnbeh.2016.00214

    • URL

      https://pure.teikyo.jp/en/publications/a6847ad9-53a8-41c5-a763-7165cfdb32ad

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.2016

    • Author(s)
      Yamasaki M, Fukaya M, Yamazaki M, Azechi H, Natsume R, Abe M, Sakimura K, Watanabe M
    • Journal Title

      J Neurosci

      Volume: 36 Issue: 15 Pages: 4296-4312

    • DOI

      10.1523/jneurosci.4178-15.2016

    • NAID

      120005849916

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] GluD2 endows parallel fiber-Purkinje cell synapses with a high regenerative capacity.2016

    • Author(s)
      Ichikawa R, Sakimura K, Watanabe M
    • Journal Title

      J Neurosci,

      Volume: 36 Issue: 17 Pages: 4846-4858

    • DOI

      10.1523/jneurosci.0161-16.2016

    • NAID

      120005853072

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Doublet 7 shortening, doublet 5-preferential poly-Glu reduction, and beating stall of sperm flagella in Ttll9-/- mice.2016

    • Author(s)
      Konno A, Ikegami K, Konishi Y, Yang HJ, Abe M, Yamazaki M, Sakimura K, Yao I, Shiba K, Inaba K, Setou M.
    • Journal Title

      J Cell Sci.

      Volume: 129 Issue: 14 Pages: 2757-2766

    • DOI

      10.1242/jcs.185983

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.2016

    • Author(s)
      Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 12135-12135

    • DOI

      10.1038/ncomms12135

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression.2016

    • Author(s)
      Mochida, S.*, Hida, Y., Tanifuji, S., Hagiwara, A., Hamada, S., Abe, M., Huan, M., Yasumura, M., Kitajima, I., Sakimura, K., Ohtsuka, T*.
    • Journal Title

      Cell Reports

      Volume: 16 Issue: 11 Pages: 2901-2913

    • DOI

      10.1016/j.celrep.2016.08.020

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse2016

    • Author(s)
      Kono J,:Konno K, Talukder AH, Fuse T, Abe M, Uchida K, Horio S, Sakimura K, Watanabe M, Itoi K
    • Journal Title

      Brain Struc Funct

      Volume: Epub ahead of print Issue: 1 Pages: 1-28

    • DOI

      10.1007/s00429-016-1303-0

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] SCOP/PHLPP1β mediates circadian regulation of long-term recongnition memory.2016

    • Author(s)
      Kimiko Shimizu, Yodai Kobayashi, Erika Nakatsuji, Shigeki Shimba, Maya Yamazaki, Kenji Sakimura and Yoshitaka Fukada.
    • Journal Title

      Nat. Commun.

      Volume: 7 Issue: 1 Pages: 12926-12926

    • DOI

      10.1038/ncomms12926

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality.2016

    • Author(s)
      Horie M, Mekada K, Sano H, Kikkawa Y, Chiken S, Someya T, Saito K, Hossain MI, Nameta M, Abe K, Sakimura K, Ono K, Nambu A, Yoshiki A, Takebayashi H.
    • Journal Title

      Neurobiol Dis.

      Volume: 96 Pages: 271-283

    • DOI

      10.1016/j.nbd.2016.09.016

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Involvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury.2016

    • Author(s)
      Katano T, Fukuda M, Furue H, Yamazaki M, Abe M, Watanabe M, Nishida K, Yao I, Yamada A, Hata Y, Okumura N, Nakazawa T, Yamamoto T, Sakimura K, Takao T, Ito S.
    • Journal Title

      eNeuro.

      Volume: 3 Issue: 5 Pages: 0110-16

    • DOI

      10.1523/eneuro.0110-16.2016

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Forward-genetics analysis of sleep in randomly mutagenized mice2016

    • Author(s)
      Funato H and Yanagisawa M et al.
    • Journal Title

      Nature

      Volume: 539(7629) Issue: 46 Pages: 378-383

    • DOI

      10.1038/nature20142

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Roles of Cbln1 in Non-Motor Functions of Mice2016

    • Author(s)
      Otsuka S, Konno K, Abe M, Motohashi J, Kohda K, Sakimura K, Watanabe M, Yuzaki M
    • Journal Title

      Journal of Neuroscience

      Volume: 36 Issue: 46 Pages: 11801-11816

    • DOI

      10.1523/jneurosci.0322-16.2016

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Electrophysiological evidence showing muscarinic agonist-antagonist activities of N-desmethylclozapine using hippocampal excitatory and inhibitory neurons.2016

    • Author(s)
      Sugawara Y, Kikuchi Y, Yoneda M, Ohno-Shosaku T
    • Journal Title

      Brain Res

      Volume: 1642 Pages: 255-262

    • DOI

      10.1016/j.brainres.2016.03.054

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis.2016

    • Author(s)
      Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, Kawahara Y.
    • Journal Title

      Cell Reports

      Volume: 17 Issue: 8 Pages: 2004-2014

    • DOI

      10.1016/j.celrep.2016.10.073

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] LTD-like molecular pathways in developmental synaptic pruning2016

    • Author(s)
      Piochon C, Kano M, Hansel C
    • Journal Title

      Nat Neurosci

      Volume: 19 Issue: 10 Pages: 1299

    • DOI

      10.1038/nn.4389

    • URL

      https://pure.teikyo.jp/en/publications/bbb7c09e-083e-43da-8885-5b3f5d0ab743

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 生後発達期の小脳におけるシナプス刈り込みのメカニズム2016

    • Author(s)
      渡邉貴樹、上阪直史、狩野方伸
    • Journal Title

      生化学

      Volume: 88 Pages: 621-629

    • NAID

      40020998193

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders2016

    • Author(s)
      Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M.
    • Journal Title

      Nat Communications

      Volume: 7 Issue: 1 Pages: 10594-10594

    • DOI

      10.1038/ncomms10594

    • NAID

      120006535052

    • URL

      https://pure.teikyo.jp/en/publications/6d10cbbf-3e7f-4e5b-bfce-ab50e6dde489

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses2016

    • Author(s)
      Ly R, Bouvier G, Szapiro G, Prosser H, Randa11 AD, Kano M, Sakimura K, Isope P, Barbour BJ, Feltz A
    • Journal Title

      J Physiol (Lond)

      Volume: 594 Issue: 4 Pages: 915

    • DOI

      10.1113/jp271623

    • URL

      https://pure.teikyo.jp/en/publications/5c870018-eb22-4e33-8a91-643d0c72a849

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Territories of heterologous inputs onto purkinje cell dendrites are segregated by mglur1-dependent parallel fiber synapse elimination2016

    • Author(s)
      Ichikawa R, Hashimoto K, Miyazaki T, Uchigashima M, Yamasaki M, Aiba A, Kano M, Watanabe M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 113 Issue: 8 Pages: 2282

    • DOI

      10.1073/pnas.1511513113

    • NAID

      120005828473

    • URL

      https://pure.teikyo.jp/en/publications/ef6116f6-3235-46cc-b619-656ef2bb4818

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice.2015

    • Author(s)
      Aida T, Yoshida J, Nomura M, Tanimura A, Iino Y, Soma M, Bai N, Ito Y, Cui W, Aizawa H, Yanagisawa M, Nagai T, Takata N, Tanaka KF, Takayanagi R, Kano M, Gotz M, Hirase H, Tanaka K.
    • Journal Title

      Neuropsychopharmacology

      Volume: in press Issue: 7 Pages: 1660-1660

    • DOI

      10.1038/npp.2015.26

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol2015

    • Author(s)
      Kishimoto Y, Cagniard B, Yamazaki M, Nakayama J, Sakimura K, Kirino Y, Kano M.
    • Journal Title

      Front. Behav. Neurosci.

      Volume: 9 Issue: JUNE Pages: 134-134

    • DOI

      10.3389/fnbeh.2015.00134

    • URL

      https://pure.teikyo.jp/en/publications/2dbf304d-3bc8-43b9-abad-0825f823169d

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Implicit memory in monkeys: class FormattedString { value: Development of a delay eyeblink conditioning system with parallel electromyographic and high-speed video measurements }2015

    • Author(s)
      Kishimoto Y, Yamamoto S, Suzuki K, Toyoda H, Kano M, Tsukada H, Kirino Y
    • Journal Title

      PloS one

      Volume: 10 Issue: 6 Pages: e0129828-e0129828

    • DOI

      10.1371/journal.pone.0129828

    • URL

      https://pure.teikyo.jp/en/publications/e481ce02-4cf3-45c7-8b94-6da345259488

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Fever is mediated by conversion of endocannabinoid 2-arachidonoylglycerol to prostaglandin E<sub>2</sub>2015

    • Author(s)
      Yoshihiro Kita, Kenij Yoshida, Suzumi M. Tokuoka, Fumie Hamano, Maya Yamazaki, Kenji Sakimura, Masanobu Kano, Takao Shimizu
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0133663-e0133663

    • DOI

      10.1371/journal.pone.0133663

    • URL

      https://pure.teikyo.jp/en/publications/96586bdc-9aa7-4035-893d-cba8c7bd002a

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Weeding out bad waves: Towards selective cannabinoid circuit control in epilepsy2015

    • Author(s)
      Soltesz I, Alger BE, Kano M, Lee SH, Lovinger DM, Ohno-Shosaku T, Watanabe M
    • Journal Title

      Nat Rev Neurosci

      Volume: 16 Issue: 5 Pages: 264

    • DOI

      10.1038/nrn3937

    • URL

      https://pure.teikyo.jp/en/publications/85e3cf12-980d-4342-b02c-0ed431adda0d

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Consensus Paper: class FormattedString { value: Cerebellar Development }2015

    • Author(s)
      Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T
    • Journal Title

      Cerebellum

      Volume: 15 Issue: 6 Pages: 789

    • DOI

      10.1007/s12311-015-0724-2

    • URL

      https://pure.teikyo.jp/en/publications/eaabf50b-e97f-47a3-bc59-077237c36e2b

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 発達期におけるシナプス刈り込みと逆行性シグナル2015

    • Author(s)
      上阪直史、狩野方伸
    • Journal Title

      実験医学

      Volume: 33 Pages: 1386-1370

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Rational design of a high-affinity, fast, red calcium indicator R-CaMP2.2015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Journal Title

      Nat Methods

      Volume: 12 Issue: 1 Pages: 64-70

    • DOI

      10.1038/nmeth.3185

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Structure–function relationships between aldolase C/Zebrin II expression and complex spike synchrony in the cerebellum2015

    • Author(s)
      Tsutsumi S, Yamazaki M, Miyazaki T, Watanabe M, Sakimura K, Kano M, Kitamura K
    • Journal Title

      J Neurosci.

      Volume: 35 Issue: 2 Pages: 843

    • DOI

      10.1523/jneurosci.2170-14.2015

    • URL

      https://pure.teikyo.jp/en/publications/1cc3b0d1-49e6-4b07-a3f2-52dca89fc01e

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Retrograde Signaling for Climbing Fiber Synapse Elimination2015

    • Author(s)
      Uesaka N, Uchigashima M, Mikuni T, Hirai H, Watanabe M, Kano M
    • Journal Title

      Cerebellum

      Volume: 14 Issue: 1 Pages: 4

    • DOI

      10.1007/s12311-014-0615-y

    • URL

      https://pure.teikyo.jp/en/publications/3ed54d52-164e-4b27-b390-3384f770f57c

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 内因性カンナビノイドによるシナプス伝達調節2015

    • Author(s)
      狩野方伸
    • Journal Title

      お茶の水醫學雑誌

      Volume: 63 Pages: 53-65

    • Related Report
      2014 Annual Research Report
  • [Journal Article] A highly sensitive fluorescent indicator dye for calcium imaging of neural activity in vitro and in vivo2014

    • Author(s)
      Tada M, Takeuchi A, Hashizume M, Kitamura K, Kano M
    • Journal Title

      Eur J Neurosci

      Volume: 39 Issue: 11 Pages: 1720

    • DOI

      10.1111/ejn.12476

    • URL

      https://pure.teikyo.jp/en/publications/33c5e9cc-a3aa-4273-9617-0f19eb474673

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective Activation of mTORC1 Signaling Recapitulates Microcephaly, Tuberous Sclerosis, and Neurodegenerative Diseases2014

    • Author(s)
      Kassai H, Sugaya Y, Noda S, Nakao K, Maeda T, Kano M, Aiba A
    • Journal Title

      Cell Reports

      Volume: 7 Issue: 5 Pages: 1626

    • DOI

      10.1016/j.celrep.2014.04.048

    • URL

      https://pure.teikyo.jp/en/publications/d714d3c6-814c-403f-81f6-3d5a4a38414b

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain2014

    • Author(s)
      Uesaka N, Uchigashima,M, Mikuni T, Nakazawa T, Nakao H, Hirai K, Aiba A, Watanabe M, Kano M
    • Journal Title

      Science

      Volume: 344 Issue: 6187 Pages: 1020-1023

    • DOI

      10.1126/science.1252514

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol2014

    • Author(s)
      Petrenko A B, Yamazaki M, Sakimura K, Kano M, Baba H
    • Journal Title

      Behav Brain Res

      Volume: 271 Pages: 51

    • DOI

      10.1016/j.bbr.2014.05.063

    • URL

      https://pure.teikyo.jp/en/publications/601e7c75-29d8-40ca-aa22-be863d6df972

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Global scaling down of excitatory postsynaptic responses in cerebellar purkinje cells impairs developmental synapse elimination2014

    • Author(s)
      Kawata S, Miyazaki T, Yamazaki M, Mikuni T, Yamasaki M, Hashimoto K, Watanabe M, Sakimura K, Kano M.
    • Journal Title

      Cell Rep.

      Volume: 8 Issue: 4 Pages: 1119

    • DOI

      10.1016/j.celrep.2014.07.014

    • URL

      https://pure.teikyo.jp/en/publications/2079c7db-ebb4-499b-af8c-505bb234affb

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Activity-dependent gating of calcium spikes by A-type K+ channels controls climbing fiber signaling in Purkinje cell dendrites2014

    • Author(s)
      Otsu Y, Marcaggi P, Feltz A, Isope, P, Kollo M, Nusser Z, Mathieu B, Kano M, Tsujita M, Sakimura K, Dieudonné S
    • Journal Title

      Neuron

      Volume: 84 Issue: 1 Pages: 137-151

    • DOI

      10.1016/j.neuron.2014.08.035

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism2014

    • Author(s)
      Pichon, C., Kloth, A. D., Grasselli, G., Titley, H. K., Nakayama, H., Hashimoto, K., Wan, V., Simmons, D. H., Eissa, T., Nakatani, J., Cherskov, A., Miyazaki, T., Watanabe, M., Takumi T., Kano, M., Wang S. S-H. and Hansel, C.
    • Journal Title

      Nat. Commun.

      Volume: 5 Issue: 1 Pages: 5586-5586

    • DOI

      10.1038/ncomms6586

    • URL

      https://pure.teikyo.jp/en/publications/0b75dfc4-6db1-4d67-834f-289c5e61bd65

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Endocannabinoid-mediated retrograde modulation of synaptic transmission2014

    • Author(s)
      Ohno-Shosaku T, Kano M
    • Journal Title

      Curr Opin Neurobiol

      Volume: 29 Pages: 1-8

    • NAID

      120005435504

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Control of synaptic function by endocannabinoid-mediated retrograde signaling2014

    • Author(s)
      Kano M
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 90 Issue: 7 Pages: 235-250

    • DOI

      10.2183/pjab.90.235

    • NAID

      130004678273

    • ISSN
      0386-2208, 1349-2896
    • URL

      https://pure.teikyo.jp/en/publications/1930ac4f-f5d4-4a9f-b2d9-f36b660c1d1d

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural circuits: class FormattedString { value: Japan }2014

    • Author(s)
      Kawaguchi Y, Kano M
    • Journal Title

      Front Neural Circuits

      Volume: 8 Issue: November Pages: 135-135

    • DOI

      10.3389/fncir.2014.00135

    • URL

      https://pure.teikyo.jp/en/publications/0d2efb23-564c-447c-8abc-b716286dd848

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脳の機能発達を担うシナプス刈り込みの機構2014

    • Author(s)
      上阪直史、川田慎也、狩野方伸
    • Journal Title

      Brain and Nerve

      Volume: 9 Pages: 1069-1077

    • NAID

      40020203342

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord2014

    • Author(s)
      Bhumbra G, Bannatyne A, Watanabe M, Todd AJ, Maxwell D, Beato M
    • Journal Title

      J Neurosci,

      Volume: 39 Issue: 3 Pages: 419

    • DOI

      10.1111/ejn.12470

    • URL

      https://pure.teikyo.jp/en/publications/4d02824e-7e74-4a1f-bbf3-885bea51fedf

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The synaptic targeting of mGluR1 by Its carboxyl-terminal domain is crucial for cerebellar function2014

    • Author(s)
      Yoshiaki Ohtani, Mariko Miyata, Kouichi Hashimoto, Toshihide Tabata, Yasushi Kishimoto, Masahiro Fukaya, Daisuke Kase, Hidetoshi Kassai, Kazuki Nakao, Tatsumi Hirata, Masahiko Watanabe, Masanobu Kano, Atsu Aiba
    • Journal Title

      Journal of Neuroscience

      Volume: 34 Issue: 7 Pages: 2702

    • DOI

      10.1523/jneurosci.3542-13.2014

    • URL

      https://pure.teikyo.jp/en/publications/54b9ccbe-8bfa-4c14-8ee3-4790e39ca6e8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Endocannabinoid-mediated retrograde modulation of synaptic transmission2014

    • Author(s)
      Ohno-Shosaku T, Kano M
    • Journal Title

      Curr Opin Neurobiol

      Volume: 29 Pages: 1

    • DOI

      10.1016/j.conb.2014.03.017

    • NAID

      120005435504

    • URL

      https://localhost/en/publications/270a8d44-3672-4f9d-831b-9195c30d92be

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin2013

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y; Takemoto-Kimura S, Kitamura K, Kano M, Bito H.
    • Journal Title

      Cell Reports

      Volume: 3 Issue: 4 Pages: 978

    • DOI

      10.1016/j.celrep.2013.03.033

    • URL

      https://pure.teikyo.jp/en/publications/099c8509-5cbe-4e1e-bd10-f26e5d3d26b1

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Protocadherin 17 regulates presynaptic assembly in topographic corticobasal ganglia circuits2013

    • Author(s)
      Hoshina N, Tanimura A, Yamasaki M, Inoue T, Fukabori R, Kuroda T, Yokoyama K, Tezuka T, Sagara H, Hirano S, Kiyonari H, Takada M, Kobayashi K, Watanabe M, Kano M, Nakazawa T, Yamamoto T
    • Journal Title

      Neuron

      Volume: 78 Issue: 5 Pages: 839

    • DOI

      10.1016/j.neuron.2013.03.031

    • URL

      https://localhost/en/publications/9a3f8593-f1a7-4ad9-9e1b-b33363b03e50

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Arc/Arg3.1 Is a Postsynaptic Mediator of Activity-Dependent Synapse Elimination in the Developing Cerebellum2013

    • Author(s)
      Mikuni et al.
    • Journal Title

      Neuron

      Volume: 78 Issue: 6 Pages: 1024

    • DOI

      10.1016/j.neuron.2013.04.036

    • URL

      https://localhost/en/publications/45873faa-8953-4f91-bb47-c38e82a6dd77

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diacylglycerol lipase a manipulation reveals developmental roles for intercellular endocannabinoid signaling2013

    • Author(s)
      Keimpema E, Alpar A, Howell F, Malenczyk K, Hurd YL,Watanabe M, Sakimura K, Kano M, Doherty P, Harkany T
    • Journal Title

      Scientific Rep.

      Volume: 3 Issue: 1 Pages: 2093-2093

    • DOI

      10.1038/srep02093

    • URL

      https://pure.teikyo.jp/en/publications/f1fc2703-e640-4eb8-ba3e-4a1ca87af3db

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional labeling of neuronal ensemble and axonal projections in vivo using a synthetic activity-dependent promoter E-SARE.2013

    • Author(s)
      Kawashima T, Kitamura K, Suzuki K, Nonaka M, Kamijo S, Takemoto-Kimura S, Kano M, Okuno H, Ohki K, Bito H.
    • Journal Title

      Nature Methods

      Volume: 10 Issue: 9 Pages: 889-895

    • DOI

      10.1038/nmeth.2559

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol.2013

    • Author(s)
      Hashimotodani Y, Ohno-Shosaku T, Tanimura A, Kita Y, Sano Y, Shimizu T, Di Marzo V, Kano M.
    • Journal Title

      Journal of Physiology

      Volume: 591 Issue: 19 Pages: 4765-4776

    • DOI

      10.1113/jphysiol.2013.254474

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disruption of cerebellar microzonal organization in GluD2 (Glurδ2) knockout mouse2013

    • Author(s)
      Hashizume M, Miyazaki T, Sakimura K, Watanabe M, Kitamura K, Kano M
    • Journal Title

      Front Neural Circuits

      Volume: 7 Issue: JUL Pages: 130-130

    • DOI

      10.3389/fncir.2013.00130

    • URL

      https://pure.teikyo.jp/en/publications/a05cd142-1b1f-4f89-9709-956a9653162d

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spike timing-dependent selective strengthening of single climbing fibre inputs to Purkinje cells during cerebellar development2013

    • Author(s)
      Yoshinobu Kawamura, Hisako Nakayama, Kouichi Hashimoto, Kenji Sakimura, Kazuo Kitamura and Masanobu Kano.
    • Journal Title

      Nat Commun.

      Volume: 4 Issue: 1 Pages: 2732-2732

    • DOI

      10.1038/ncomms3732

    • URL

      https://pure.teikyo.jp/en/publications/2e99c36e-a82d-4bec-8614-0103e8d0a7c9

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum2013

    • Author(s)
      Kamikubo, Y., Shimomura, T., Fujita, Y., Tabata, T., Kashiyama, T., Sakurai, T., Fukurotani, K., Kano, M.
    • Journal Title

      J. Neurosci

      Volume: 33 Issue: 47 Pages: 18661

    • DOI

      10.1523/jneurosci.5567-12.2013

    • URL

      https://pure.teikyo.jp/en/publications/09ec493e-abbe-4c57-9b35-dcde2bcd5f9c

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synapse elimination in the developing cerebellum2013

    • Author(s)
      Hashimoto K, Kano M.
    • Journal Title

      Cell Mol Life Sci

      Volume: 70 Issue: 24 Pages: 4667

    • DOI

      10.1007/s00018-013-1405-2

    • URL

      https://pure.teikyo.jp/en/publications/44448406-536f-49c9-b904-bc53122968b6

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Molecular, cellular and circuit mechanisms of activity-dependent synapse elimination in the developing cerebellum2019

    • Author(s)
      Kano M
    • Organizer
      International Symposium : Current Perspectives on Functional and Dysfunctional Neural Circuits
    • Related Report
      2018 Annual Research Report
  • [Presentation] Discovery and investigation of cerebellar long-term depression at Masao Ito's lab2019

    • Author(s)
      Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Reduced synaptic inputs in prefrontal cortex by lack of a mental disorder-related epigenetic factor2019

    • Author(s)
      Nagahama K, Sakoori K, Watanabe T, Uesaka N, Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Fndc3b promotes climbing fiber synapse elimination partly by inhibiting STAT3 in the cerebellum2019

    • Author(s)
      Kushibe K, Mercier C, Watanabe T, Miyazaki T, Yamasaki M, Watanabe M, Uesaka N, Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Activity-dependent synapse elimination in the developing cerebellum2019

    • Author(s)
      Uesaka N, Kao TH, Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Accelerated climbing fiber synapse elimination in cerebellar Purkinje cells lacking protocadherin 102019

    • Author(s)
      Watanabe T, Inoue S, Akamatsu T, Suzuki H, Abe M, Sakimura K, Uesaka N, Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Modulation of dentate granule cell activity during fear memory extinction in freely moving mice2019

    • Author(s)
      Carrier-Ruiz A, Sugaya Y, Kano M
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (第9回アジア・オセアニア生理学会連合2019年大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Neural circuit mechanisms of synapse elimination in the developing cerebellum2018

    • Author(s)
      Kano M
    • Organizer
      The 9th International Symposium of the Society for Research on the Cerebellum and Ataxias
    • Related Report
      2018 Annual Research Report
  • [Presentation] Mechanisms underlying climbing fiber synapse elimination during postnatal cerebellar development2018

    • Author(s)
      Kano M
    • Organizer
      The 75th FUJIHARA Seminar : Cerebellum as a CNS Hub - from its evolution to therapeutic strategy
    • Related Report
      2018 Annual Research Report
  • [Presentation] Neural circuit mechanisms underlying activity-dependent synapse elimination in the developing cerebellum2018

    • Author(s)
      Kano M
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Retrograde BDNF signaling required for synapse elimination in the developing cerebellum2018

    • Author(s)
      Choo M, Uesaka N, Watanabe M, Sakimura K, Kano M
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Impaired synapse development in mouse medial prefrontal cortex by deletion of a histone-modifying enzyme implicated in psyciatric disorder2018

    • Author(s)
      Nagahama K, Sakoori K, Watanabe T, Uesaka N, Kano M
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Roles of synaptic transmission in climbing fiber to Purkinje cell synapse elimination during postnatal cerebellar development2018

    • Author(s)
      Kao T-H, Matsuyama K, Uesaka N, Kano M
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Dentate granule cell activity during fear memory extinction in freely moving mice2018

    • Author(s)
      Carrier-Ruiz A, Sugaya Y, Kano M
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Near-infrared deep brain stimulation via upconversion nanoparticle-mediated optogenetics2018

    • Author(s)
      He L, Chen S, Zachary Weitemier A, Wang X, Tao Y, Huang AJY, Hashimotodani Y, Kano M, Iwasaki H, Parajuli LK, Okabe S, Tsutsui-Kimura I, F-Tanaka K, McHugh TJ
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society (第41回日本神経科学大会)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Near-infrared deep brain stimulation via upconversion nanoparticle-mediated optogenetics2018

    • Author(s)
      Chen S, Weitemier AZ, Zeng X, HE L, Wang X, Tao Y, Huang A, Hashimotodani Y, Kano M, Iwasaki H, Parajuli LK, Okabe S, Loong D, All AH, Tsutsui-Kimura I, Tanaka KF, Liu X, Mchugh TJ
    • Organizer
      Society for Neuroscience 2018 Annual Meeting
    • Related Report
      2018 Annual Research Report
  • [Presentation] Function of the adult-born neurons in memory consolidation during sleep2018

    • Author(s)
      Kumar D, Koyanagi I, Carrier-Ruiz A, Vergara P, Sugaya Y, Srinivasan S, Kasuya M, Yu T-S, Vogt K, Muratani M, Ohnishi T, Singh S, Teixeira CM, Nondhalee P, Naoi T, Mchugh TJ, Kernie SG, Kano M, Sakurai T, Yanagisawa M, Sakaguchi M
    • Organizer
      Society for Neuroscience 2018 Annual Meeting
    • Related Report
      2018 Annual Research Report
  • [Presentation] Activity of cerebellar climbing fibers represents forelimb movements during voluntary lever-pull task in mice2018

    • Author(s)
      Hidaka N, Tsutsumi S, Ikezoe K, Isomura Y, Kano M, Kitamura K
    • Organizer
      Society for Neuroscience 2018 Annual Meeting
    • Related Report
      2018 Annual Research Report
  • [Presentation] Organization of the functional inputs from the sensorimotor cortex to the cerebellum revealed by transcranial optogenetic mapping2018

    • Author(s)
      Choo M, Hira R, Matsuzaki M, Ikezoe K, Augustine GJ, Kano M, Kitamura K
    • Organizer
      Society for Neuroscience 2018 Annual Meeting
    • Related Report
      2018 Annual Research Report
  • [Presentation] Mechanisms of activity-dependent synapse elimination in the developing cerebellum2018

    • Author(s)
      Kano M
    • Organizer
      The 8th Brain Research Institute International Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Multiple phases of activity-dependent synapse elimination in the developing cerebellum2018

    • Author(s)
      Kano M
    • Organizer
      The 4th Symposium of NEUROSCIENCE NETWORK IN KOBE
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 生後発達期のマウス前頭前野のニューロンにおいて統合失調症患関連分子Setdlaをノックダウンした場合のシナプス伝達の減弱2018

    • Author(s)
      長濱健一郎、佐郡和人、渡邉貴樹、上阪直史、狩野方伸
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dentate granule cell activity during fear memory extinction in freely moving mice2018

    • Author(s)
      Carrier-Ruiz A, Sugaya Y, Kano M
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of gene-manipulated methods for animal models, mouse, rat and marmoset, for the analysis of brain function2018

    • Author(s)
      K. SAKIMURA
    • Organizer
      The 8th BRI International Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 運動学習および行動柔軟性に影響をおよぼす因子 : カンナビノイド系とテオブロミン2018

    • Author(s)
      米田貢、谷上颯、臼田明莉、中川雅崇、菊池ゆひ、杉本直俊、少作隆子
    • Organizer
      第95回 日本生理学会大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Anatomical pathway for perioral sensory signals to the inferior olive in the mouse.2018

    • Author(s)
      Kubo, R., Hashimoto, K.
    • Organizer
      第95回 日本生理学会大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 神経細胞のResonance特性に関わるイオンチャネルの解析2017

    • Author(s)
      橋本浩一, 槇殿佳子, 中山寿子, 山崎美和子, 宮崎太輔, 小林和人, 渡辺雅彦, 狩野方伸, 崎村建司
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2017-03-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 2-AG合成酵素DGLα欠損マウスはCB1受容体欠損マウスと同様のレバー押し学習障害を示す2017

    • Author(s)
      米田貢, 谷上颯, 臼田明莉, 田端祐樹, 菊池ゆひ, 少作隆子
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2017-03-29
    • Related Report
      2016 Annual Research Report
  • [Presentation] Theobromine crosses the blood brain barrier resulting in increased phosphorylation of vasodilator-stimulated phosphoprotein and cAMP-response element-binding protein in the mouse brain2017

    • Author(s)
      Sugimoto N, Katakura M, Matsuzaki K, Yoneda M, Sumiyoshi E, Ohno-Shosaku T, Yachie A, Shido O.
    • Organizer
      21st International Conference of FFC
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2017-03-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanisms of developmental synapse elimination in the cerebellum2017

    • Author(s)
      狩野方伸
    • Organizer
      Symposium on “Brain Networks : From Molecules to Diseases”
    • Place of Presentation
      Nanyang(シンガポール)
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Roles of RNA editing in neuropathic pain after peripheral nerve injury神経障害性疼痛におけるRNA編集異常とその役割2017

    • Author(s)
      内田仁司、崎村建司、伊藤誠二
    • Organizer
      第90回日本薬理学会
    • Place of Presentation
      長崎ブリックホール(長崎県・長崎市)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] Regulation of climbing fiber synapse elimination in the developing cerebellum by retrograde signaling2017

    • Author(s)
      Uesaka N, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Functions of cerebellar modules during goal-directed behavior2017

    • Author(s)
      Kitamura K, Tsutsumi S, Hidaka N, Isomura Y, Matsuzaki M, Sakimura K, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Endocannabinoid, 2-arachidonoylglycerol plays important roles during neuronal circuit formation in the mouse barrel cortex2017

    • Author(s)
      Kimura F, Itami C, Sakimura K, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Key roles of cannabinoid CBI receptor and 2-arachidonoylglycerol in the regulation of excitatory synaptic transnission in the bed nucleus of the stria terminalis and neuropathic pain2017

    • Author(s)
      Kato A, Sakoori K, Sakimura K, Sugaya Y, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] BDNF to TrkB sigaling promotes climbing fiber synapse elimination in the developing cerebellum2017

    • Author(s)
      Choo MJ, Miyazaki T, Yamasaki M, Kawamura M, Nakazawa T, Tanimura A, Uesaka N, Watanabe M, Sakimura K, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Involvement of Endc3b, a fibronectin type Ⅲ domain-containing protein, in climbing fiber synapse elimination during postnatal cerebellar development2017

    • Author(s)
      Mercier C, Watanabe T, Miyazaki T, Watanabe M, Uesaka N, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Calcium channels in cerebellar synapses bind to extracellular ligand and organize presynaptic active zones2017

    • Author(s)
      Nishimune H, Mizushige T, Uesaka N, Numata T, Chen J, Badawi Y, Mori Y, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Maturation of cerebellar climbig fiber and Purkinje cell population activities during postnatal development2017

    • Author(s)
      Mahoney M, Good JM, Miyazaki T, Tanaka KF, Sakimura K, Watanabe M, Kitamura K, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Activation of mTORC1 signaling in cerebellar Purkinje cells causes cell death and hypertrophy of Purkinje cells2017

    • Author(s)
      Sakai Ym, Kassai H, Nakayama H, Nakao K, Maeda T, Hahimoto K, Kano M, Aiba A
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Phospholipase Cβ3 is required for climbig fiber synapse elimination in aldolase C-positive compartments of the developing mouse cerebellum2017

    • Author(s)
      Rai Y, Watanabe T, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optogenetic analysis of projections from the supramammillary nuleus to the dentate gyrus of the hippocampal formation2017

    • Author(s)
      Hashimotodani Y, Yanagawa Y, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Screening of autism spectrum disorder-associated molecules that are imvolved in climbing fiber-Purkinje cell synapse elimination in the developing mouse cerebellum2017

    • Author(s)
      Watanabe T, Inoue S, Uesaka N, Kano M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Two-photon imaging of cerebellar climbing fiber signals during a voluntary movement2017

    • Author(s)
      Hidaka N, Tsutsumi S, Ikezoe K, Isomura Y, Kano M, Kitamura K
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Serotonin Rebalances Cortical Tuning and Behavior Linked to Autism Symptoms in 15q11-13 CNV Mice2017

    • Author(s)
      Nakai N, Nagano M, Saitow F, Watanabe Y, Kawamura Y, Mizuma H, Onoue H, Tamada K, Monai H, Hirase H, Miyazaki T, Watanabe M, Okabe S, Kano M, Hahimoto K, Suzuki H, Takumi T
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Molecular, cellular, and circuit mechanisms of developmental synapse elimination in the cerebellum2017

    • Author(s)
      Kano M
    • Organizer
      Gordon Research Conference on Cerebellum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] BDNF to TrkB signaling regulated by mGlul promotes climbing fiber synapse elimination in the developing cerebellum2017

    • Author(s)
      Kano M
    • Organizer
      9th International Meeting on Metabotropic Glutamate Receptors
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The metabotropic glutamate receptor subtype 1 mediates visual-experience dependent maintenance of synaptic connectivity in the dorsal lateral geniculate nucleus2017

    • Author(s)
      M. NARUSHIMA, M. UCHIGASHIMA, Y. YAGASAKI, T. HARADA, Y. NAGUMO, N. UESAKA, K. HASHIMOTO, A. AIBA, M. WATANABE, M. MIYATA, M. KANO
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 duplication mice2017

    • Author(s)
      N. NAKAI, M. NAGANO, F. SAITOW, Y. WATANABE, Y. KAWAMURA, K. TAMADA, H. MONAI, H. HIRASE, H. MIZUMA, H. ONOE, T. MIYAZAKI, M. WATANABE, S. OKABE, M. KANO, K. HASHIMOTO, H. SUZUKI, T. TAKUMI
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rational engineering of XCaMPs, a multicolor GECI suite for In vivo imaging of brain circuit dynamics2017

    • Author(s)
      M. INOUE, A. TAKEUCHI, S. MANITA, S. -I. HORIGANE, R. KAWAKAMI, K. YAMAGUCHI, M. SAKAMOTO, H. YOKOYAMA, R. KIM, S. TAKEMOTO-KIMURA, M. ABE, K. SAKIMURA, T. NEMOTO, M. KANO, H. FUJII, K. KITAMURA, H. BITO
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CARD HyperOvaを用いたBNラットの過剰排卵誘起処置の有用性2017

    • Author(s)
      中務胞、夏目里恵、崎村建司
    • Organizer
      第64回日本実験動物学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] GluD1・Cbln1複合体は分界条床核GABA作動性神経と結合腕傍核由来の神経終末との接着に関与する2017

    • Author(s)
      今野幸太郎、森さくら、崎村建司、柚崎通介、渡辺雅彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] GABAニューロン前駆細胞の一部はグリア細胞に分化する2017

    • Author(s)
      江角重行、柳川右千夫、崎村建司、鹿川哲史、石龍徳、竹林浩秀、玉巻伸章
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2017

    • Author(s)
      笹岡俊邦、佐藤朝子、知見聡美、大久保直、阿部学、川村名子、中尾聡宏、小田佳奈子、酒井清子、前田宜俊、神保幸弘、田中稔、山本美丘、佐藤俊哉、藤沢信義、崎村建司、南部篤
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大脳皮質Arc経路活性化による遠隔記憶セルアンサンブルの制御2017

    • Author(s)
      金亮、酒井一輝、川島尚之、近藤弥生、井上昌俊、野中美応、坂本雅行、岡本理子、阿部学、崎村建司、今吉格、奥野浩行、尾藤晴彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Loss of autism susceptibility gene, Auts2 induces the excessive synaptic formation in mouse forebrains.2017

    • Author(s)
      山田 光代、堀 啓、坂本 亜沙美、阿部 学、崎村建司、曽根 雅紀、星野 幹雄
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] SRF転写活性化因子MKL2の機能解析 : 新規アイソフォームSOLOISTを中心としてFunctional analyses of SRF coactivator MKL2 including a novel isoform SOLOIST2017

    • Author(s)
      田邉 広樹、石橋 悠太、庄司 しずく、久保 友喜美、袴田 知之、田中 拓郎、森 寿、和泉 宏謙、崎村 健司、福地 守、津田 正明、田渕 明子
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CAST/ELKS deletion from photoreceptor causes blindness by synaptic and neural remodeling during retinal maturation2017

    • Author(s)
      萩原 明、北原 陽介、Vogl Christian、阿部 学、橘田 涼、太田 啓介、中村 桂一郎、崎村 建司、Moser Tobias、西 昭徳、大塚 稔久
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CRF-Venus ΔNeoマウスの分界条床核外側部CRHニューロンのシナプス入力の性差-ホルマリンテストを用いて Sex specific changes in mEPSC of CRH neurons in the lateral BST in CRF-Venus △Neo mice in association with formalin test2017

    • Author(s)
      萩原 裕子、崎村 建司、井樋 慶一、舩橋 利也
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] プルキンエ細胞に発現するカルシニューリンB1サブユニットは抑制性シナプス形成過程において適切なプレーポストシナプスの接着に関わっている2017

    • Author(s)
      宮﨑太輔、崎村建司、渡辺雅彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ドレブリンはmGluR5およびNMDA受容体依存性LTD誘導に関わる2017

    • Author(s)
      児島伸彦、安田浩樹、崎村建司、白尾智明
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Generation and analysis of cerebellar granule cell-specific neurexins triple knockout mice2017

    • Author(s)
      植村 健、鈴木 絵美、小池 梨絵、川瀨 詩織、栗原 大河、崎村 建司、三品 昌美、田渕 克彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A role of actin remodeling in cortical interneuron for critical period plasticity2017

    • Author(s)
      候 旭濱、國見 順子、崎村 建司、杉山 清佳
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Disruption of AMPA receptor-palmitoylation leads excitatory/inhibitory imbalance and elevated seizure susceptibility2017

    • Author(s)
      伊藤 政之、山下 真梨子、山田 大輔、奥野 浩行、阿部 学、山崎 真弥、夏目 里恵、金子 雅規、貝塚 利恵、崎村 建司、関口 正幸、和田 圭司、星野 幹雄、三品 昌美、林 崇
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Behavioral analyses of forebrain specific knock-out mice of an orphan metabotropic receptor Prrt3 and screening of small molecule library toward identification of its ligand2017

    • Author(s)
      陳 以珊、山本 友美、周 麗、夏目 里恵、今野 幸太郎、上杉 志成、渡辺 雅彦、高雄 啓三、宮川 剛、崎村建司、久保 義弘
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Depression-like behavior in the GluD1 deficient mice was remedied by antidepressants2017

    • Author(s)
      中本千尋、夏目 里恵、阿部 学、川村 名子、内田 仁司、渡辺 雅彦、崎村建司
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Biochemical analysis of phosphorylated CAST/ELKS in mice brain2017

    • Author(s)
      浜田 駿、阿部 学、崎村 建司、大塚 稔久
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Gene expression and behavior analysis of microglial voltage-gated proton channels in mouse2017

    • Author(s)
      河合 喬文、高雄 啓三、崎村建司、宮川 剛、岡村 康司
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Classification of corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus according to their differential neural projections2017

    • Author(s)
      堀尾 修平、山形 聡、小林 憲太、加藤 成樹、崎村 建司、上山 敬司、小林 和人、井樋 慶一
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Generation of corticotropin-releasing factor neuron-selective vasopressin knockout mouse : unravelling the physiological role of vasopressin expressed in the parvocellular neurons in the hypothalamus2017

    • Author(s)
      山形 聡、Talukder Hossain Ashraf、渡辺 真秀、周 麗、夏目 里恵、阿部 学、蔭山 和則、大門 眞、崎村 建司、井樋 慶一
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Orexin modulates Behavioral Fear Expression through Noradrenergic Neurons in the Locus Coeruleus2017

    • Author(s)
      高橋 徹、征矢 晋吾、Thomas J Mchugh、前島 隆、阿部 学、崎村 建司、櫻井 武
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Identification and characterization of brain-enriched guanylate kinase-associated protein as a neuropathic pain-related protein in the spinal dorsal horn2017

    • Author(s)
      片野 泰代、福田 正史、山崎 真弥、、阿部 学、渡辺 雅彦、矢尾 育子、奥村 宣明、中澤 敬信、山本 雅、崎村 建司、高尾 敏文、伊藤 誠二
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Purkinje cells are more vulnerable to the specific depletion of cathepsin D than to that of Atg72017

    • Author(s)
      小池 正人、柴田 昌宏、砂堀 毅彦、山口 隼司、崎村 建司、小松 雅明、田中 啓二、内山 安男
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The role of Auts2 in the dentate gyrus development2017

    • Author(s)
      江草 早紀、堀 啓、坂本 亜沙美、阿部 学、崎村 建司、郷 康広、星野 幹雄
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Visualizing single-neuron identity specified by Pcdh-b cluster2017

    • Author(s)
      金子 涼輔、阿部 学、高鶴 裕介、渡辺 雅彦、崎村 建司、柳川 右千夫、八木 健
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] NKによるGAP-43のリン酸化は軸索成長を制御する Phosphorylation of GAP-43 by JNK regulates axonal growth2017

    • Author(s)
      河嵜 麻実、岡田 正康、小林 大紀、野住 素広、崎村 建司、仁科 博史、武内 恒成、五十嵐 道弘
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Sleep/wakefulness behavior after ablation of central serotonergic neuron2017

    • Author(s)
      岩崎 加奈子、柿崎 美代、阿部 学、崎村 建司、船戸 弘正、柳沢 正史
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] RNA編集酵素ADAR2は神経障害性疼痛に関与する RNA editing enzyme ADAR2 contributes to neuropathic pain2017

    • Author(s)
      内田 仁司、崎村 建司、伊藤 誠二
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Depression-like behavior in the GluD1 deficient mice was remedied by antidepressants.2017

    • Author(s)
      Chihiro Nakamoto、Rie Natsume, Manabu Abe, Meiko Kawamura, Hitoshi Uchida, Masahiko Watanabe, Kenji Sakimura
    • Organizer
      26th Meeting of the International Society for Neurochemistry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Roles of Arc/arg3.1 on surface expression dynamics of AMPA receptors during structural plasticity and on cognitive refinement processes2017

    • Author(s)
      H. OKUNO、Y. ISHII, T. ENDO, M. UEHARA, Y. SUZUKI, K. MINATOHARA, A. ARAKI, M. ABE, I. IMAYOSHI, M. KAKEYAMA, K. SAKIMURA, H. BITO
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aifl-iCre knock-in mouse line : A tool for conditional gene manipulation in microglia2017

    • Author(s)
      M. ABE、F. PENG, K. SAKIMURA ;
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging In vivo2017

    • Author(s)
      M. SAKAMOTO、M. INOUE、K. SAKAI、S. KOBARI、S. TAKEMOTO-KIMURA, M. ABE, K. SAKIMURA, H. BITO
    • Organizer
      Society for Neuroscience 2017 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ラット卵巣卵胞内卵子の成熟培養なしでの体外受精2017

    • Author(s)
      中務 胞、夏目里恵、崎村建司
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 発生および慢性疼痛下の一次知覚神経におけるRNA編集の変動2017

    • Author(s)
      内田 仁司、松村伸治、崎村建司、伊藤 誠二
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ニューロンIDの可視化 ~クラスター型プロトカドヘリンの発現解析~2017

    • Author(s)
      金子 涼輔、阿部学、高鶴裕介、渡辺雅彦、崎村建司、柳川 右千夫、八木 健
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] PKN1はリンパ球の細胞運動・トラフィッキングを制御する2017

    • Author(s)
      窪内 康二、團野紗莉、野町昭、平田多佳子、松尾一彦、中山隆志、佐藤亮介、杉浦麗子、阿部学、崎村建司、若菜茂晴、大崎博之、鴨志田伸吾、向井 秀幸
    • Organizer
      第40回日本分子生物学会年会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 運動学習における内因性カンナビノイド2-AGとCB1受容体の関与2017

    • Author(s)
      米田貢、谷上颯、中川雅崇、臼田明莉、田端佑樹、少作隆子
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 3レバーオペラント課題における2-AG合成酵素DGLα欠損マウスの適応行動の障害2017

    • Author(s)
      米田貢, 谷上颯, 田端佑樹, 越後亮介, 少作隆子
    • Organizer
      日本生物学的精神医学会・日本神経精神薬理学会 合同年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] マウスヒゲ領域から下オリーブ核に至る感覚経路の解析.2017

    • Author(s)
      久保怜香、橋本浩一
    • Organizer
      生理学研究所研究会「シナプス・神経回路機能の時空間制御」
    • Related Report
      2017 Annual Research Report
  • [Presentation] Microglia Dependent Development of Neuronal Circuits in the Cerebellum.2017

    • Author(s)
      Nakayama, H., Abe, M., Morimoto, M., Sakimura, K., Hashimoto, K.
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Activation of mTORC1 signaling in cerebellar Purkinje cells causes cell death and hypertrophy of Purkinje cells.2017

    • Author(s)
      Sakai, Y., Kassai, H., Nakayama, H., Nakao, K., Maeda, T., Hashimoto, K., Kano, M., Aiba, A.
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Genetic manipulation of mTORC1 signaling in mouse cerebellar Purkinje cell2016

    • Author(s)
      H. KASSAI1, Y. SAKAI1, H. NAKAYAMA4, T. MAEDA2, K. HASHIMOTO4, M. KANO3, A. AIBA
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2016-11-14
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Automated 3D analysis of confocal microscopy images by 3D-ACE reveals widespread molecular and cellular adaptions in the spinal nociceptive circuitry of monoacylglycerol lipase knockout mice2016

    • Author(s)
      C. I. Pongor, S. G. Woodhams, B. Benjamin, B. Dudok, L. Barna, M. Kano, K. Sakimura, M. Watanabe, I. Katona
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Functional differeces in climbing fiber inputs to distinct cerebellar stripes during goal-directed behavior2016

    • Author(s)
      S. Tsutsumi, N. Hidaka, Y. Isomura, M. Matsuzaki, K. Sakimura, M. Kano, K. Kitamura
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Physiological and morphological roles of endocannabinoid 2-arachidonoylglycerol in the developing neuronal circuit in the mouse barrel cortex2016

    • Author(s)
      Chiaki Itami, K. Sakimura, M. Kano, F. Kimura
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] SCOP-dependent circadian regulation of memory formation for novel object2016

    • Author(s)
      K. Shimizu, Y. Kobayashi, E. Nakatsuji, M. Yama zaki, K. Sakimura, Y. Fukada
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDiego(アメリカ)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Distribution of cortictropin-releasing factor neurons in the mouse brain : a study using cortisotropin-releasing factor modified yellow fluorescent protein knock-in mouse2016

    • Author(s)
      K. Itoi, J. Kono, K. Konno, A. H. Talukder, T. Fuse, K. Uchida, S. Yamagata, S. Horio, M. Abe, M. Watanabe, K. Sakimura
    • Organizer
      The 46th Annual Meeting of the Society for Neuroscience (Neuroscience2016)
    • Place of Presentation
      SanDeigo(アメリカ)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 細胞膜resonance特性に関わるイオンチャネル2016

    • Author(s)
      橋本浩一、槇殿佳子、中山寿子
    • Organizer
      第68回 日本生理学会 中国四国地方会
    • Place of Presentation
      岡山大学(岡山県・岡山市)
    • Year and Date
      2016-11-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Neuronal activity and retrograde signaling that regulate synapse elimination in the developing cerebellum2016

    • Author(s)
      狩野方伸
    • Organizer
      The 47th NIPS International Symposium “Decoding Synapses”
    • Place of Presentation
      生理学研究所(兵庫県・岡崎市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] デルタ型グルタミン酸受容体サブユニット機能とその量的関連2016

    • Author(s)
      中本千尋、川村名子、夏目里恵、阿部学、渡辺雅彦、崎村建司
    • Organizer
      第59回日本神経化学会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] Ion channels responsible for the resonant property of neurons in the inferior olive.2016

    • Author(s)
      橋本浩一、中山寿子、松本佳子
    • Organizer
      第59回日本神経化学会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] マウス受精卵電気穿孔法を用いたCRISPR/Cas9システムによる内在性タンパク質へのタグ付加の試み2016

    • Author(s)
      阿部学、夏目里恵、中務胞、崎村建司
    • Organizer
      第1回 ゲノム編集学会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Theobromine crosses the blood brain barrier in vivo resulting in increased phosphorylation of vasodilatorstimulated phosphoprotein in the mouse brain2016

    • Author(s)
      Sugimoto N, Katakura M, Matsuzaki K, Ohno-Shosaku T, Yachie A, Shido O.
    • Organizer
      Physiology 2016
    • Place of Presentation
      Dublin(イギリス)
    • Year and Date
      2016-07-30
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cerebellar lobules receive spatiotemporally specific inputs from the cerebral cortex2016

    • Author(s)
      Myeong Jeong Choo, Riichiro Hira, Masanori Matsuzaki, Masanobu Kano, Kazuo Kitamura
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] GLuD1 and Cbln1 interation plays an important role in synapse formation between particular neurochemical nucleus and dorsolateral geniculate nucleus2016

    • Author(s)
      Kohtaro Konno, Koji Nishikawa, Shinji Yamada, Michisuke Yuzaki, Kenji Sakimura, Masahiko Watanabe
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] Roles of the endocannabinoid 2-arachidonoylglycerol in neuronal circuit development of the mouse barrel cortex2016

    • Author(s)
      Chiaki Itami, Kenji Sakimura, Masanobu Kano, Fumitaka Kimura
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] Visualizing single-neuron identity specified by Pcdh-b cluster2016

    • Author(s)
      Ryosuke Kaneko, Manabu Abe, Yusuke Takatsuru, Masahiko Watanabe, Kenji Sakimura, Yuchio Yanagawa, Takeshi Yagi
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] Possible role of endocannabinoid signaling in autism-like behevior in mice2016

    • Author(s)
      Kazuto Sakoori, Maya Yamazaki, Kenji Sakimura, Masanobu Kano
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] Maintenance of excitatory-inhibitory balance in brain by AMPA receptor palmitoylation2016

    • Author(s)
      Mariko Yamashita, Hiroyuki Okuno, Manabu Abe, Maya Yamazaki, Rie Natsume, Kenji Sakimura, Mikio Hoshino, Masayoshi Mishina, Takashi Hayashi
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] Layer specific contribution of diacylglycerol lipase-a to ocular dominance plasticity in the mouse visual cortexLayer specific contribution of diacylglycerol lipase-a to ocular dominance plasticity in the mouse visual cortex2016

    • Author(s)
      Katsuro Kameyama, Taisuke Yoneda, Takahiro Gotou, Keiko Terata, Kenji Sakimura, Masanobu Kano, Yoshio Hata
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Cortical intermediate GABAergic neuron progenitors divide symmertricalli to produce similar GABAergic neuron pairs2016

    • Author(s)
      Shigeyuki Esumi, Yuchio Yanagawa, Kenji Sakimura, Nobuyuki Tamamaki
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Development of GluN2B NMDA receptor subtype in spinal motoneurons : A study using Grin2b-flox mice2016

    • Author(s)
      Takae Ohno, Satoshi Fukuda, Naoyuki Murabe, Noriko Isoo, Hiroaki Mizukami, Keiya Ozawa, Kenji Sakimura, Masaki Sakurai
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Mapping of coticortropin-releasing factoe neurons in mouse brain : a study using a modified yellow flourescent protein knock-in mouse2016

    • Author(s)
      Keiichi Itoi, Junko Kono, Kotaro Konno, Talukder H. Ashraf, Katsuya Uchida, Toshimitsu Fuse, Manabu Abe, Rie Natsume, Shuhei Horio, Kenji Sakimura, Masahiko Watanabe
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Arc knockout mice exhibit specific impaiement during reversal learning phase in a spatial memory task2016

    • Author(s)
      Masahiro Uehara, Yusuke Suzuki, Toshihiro Endo, Masaki Kakeyama, Manabu Abe, Kenji Sakimura, Itaru Imayoshi, Haruhiko Bito, Hiroyuki Okuno
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] 3レバーオペラント課題を用いたマウスの運動学習および適応行動に対するテオブロミン摂取の効果2016

    • Author(s)
      米田貢, 谷上颯, 田端祐樹, 越後亮介, 杉本直俊, 少作隆子
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Transmembrane protein Dpy19L1 is required for development of the septal nucleus2016

    • Author(s)
      Keisuke Watanabe, Li Zhou, Norihisa Bizen, Rie Natsume, Manabu Abe, Kenji Sakimura, Noboru Sato, Hirohide Takebayashi
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] GluN3A colocalizes with KV4.3 at non-synaptic climbing fiber-interneuron junctions in the cerebellum2016

    • Author(s)
      Xiaohong Song, Masahiro Fukaya, Miwako Yamasaki, Motokazu Uchigashima, Kohtaro Konno, Taisuke Miyazaki, Keiko Matsuda, Chihiro Nakamoto, Isabel Perez-Otano, Michisuke Yuzaki, Kenji Sakimura, Masahiko Watanabe
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] A mutation in CACNA1G causes autosomal dominant spinocerebellar ataxia.2016

    • Author(s)
      Morino H, Matsuda Y, Muguruma K, Miyamoto R, Ohsawa R, Ohtake T, Otobe R, Watanabe M, Maruyama H, Hashimoto K, Kawakami H.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse elimination2016

    • Author(s)
      Ichikawa Ryoichi, Hashimoto Kouichi, Miyazaki Taisuke, Uchigashima Motokazu, Sakimura Kenji, Yamasaki Miwako, Aiba Atsu, Kano Masanobu, Masahiko Watanabe
    • Organizer
      10th FENS forum of Neuroscience
    • Place of Presentation
      コペンハーゲン(デンマーク)
    • Year and Date
      2016-07-03
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Theobromine, the primary methylxanthine found in Theobroma cacao, can pass through the blood-brain barrier in mice2016

    • Author(s)
      Sugimoto N, Katakura M, Matsuzaki K, Ohno-Shosaku T, Yachie A, Shido O.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego(アメリカ)
    • Year and Date
      2016-04-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小脳皮質縞状構造への運動・認知行動に関連した登上線維入力の学習による分化2016

    • Author(s)
      堤新一郎、日高直樹、磯村宜和、松崎政紀、崎村建司、狩野方伸、喜多村和郎
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-24
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] 内因性カンナビノイド2-AGは自閉症様行動に関与する2016

    • Author(s)
      佐郡和人、山崎真弥、崎村健司、狩野方伸
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-24
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] 苔状線維が放出するClqタンパク質による苔状線維-CA3シナプス機能の制御2016

    • Author(s)
      松田恵子、Timotheus Budisantosol、狩野方伸、渡辺雅彦、﨑村健司、A. Radu Aricescu、柚﨑通介
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-23
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] 1型代謝型グルタミン酸受容体による網膜-外側膝状体シナプスの成熟型結合パタンの維持2016

    • Author(s)
      鳴島円、内ヶ島基政、矢ヶ崎有希、原田武志、南雲康之、上阪直史、渡邉 貴樹、橋本浩一、饗場篤、渡辺雅彦、宮田麻理子、狩野方伸
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-22
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] 前頭側頭型認知症関連遺伝子granulinが発達期小脳のシナプス再編成を制御する2016

    • Author(s)
      上阪直史、狩野方伸
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-22
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] 大脳-小脳ループの光マッピングによる解析2016

    • Author(s)
      秋明貞、平理一郎、松崎政紀、狩野方伸、喜多村和郎
    • Organizer
      第93日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-22
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Neuroligin-2 regulates postnatal development of climbing fiber-Purkinje cell synapses in the cerebellum2015

    • Author(s)
      Lai E, Uesaka N, Kano M
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Washington DC (USA)
    • Year and Date
      2015-10-21
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rational design of ultrafast, high-affinity red calcium indicator for monitoring neuronal activity2015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S-I, Fujii H, Kamijo S, Takemoto-Kimura S, Ohkura M, Ggengyo-Ando K, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Washington DC (USA)
    • Year and Date
      2015-10-18
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rational design of a novel high-affinity, ultrafast, red calcium indicator R-CaMP22015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-30
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Retrograde signaling involved in climbing fiber synapse elimination in the developing cerebellum2015

    • Author(s)
      Kano M, Uesaka N
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-29
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] The endocannabinoid 2-arachidonoyl glycerol suppresses excitatory synaptic inputs around the inner and middle molecular layers of the dentate gyrus during seizures2015

    • Author(s)
      Sugaya Y, Yamazaki M, Sakimura K, Kano M
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-29
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Cortical excitatory/inhibitory imbalance in a mouse model for human 15q11-13 duplication2015

    • Author(s)
      Nakai N, Watanabe Y, Kawamura Y, Miyazaki T, Watanabe M, Okabe S, Kano M, Hashimoto K, Takumi T
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-29
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Knockdown of CNTNAP2 in neurons of the prefrontal cortex impairs synaptic function and causes impaired social behavior2015

    • Author(s)
      Sacai H, Sakoori K, Uesaka N, Kano M
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Identification of complex spikes in two-photon recording of Purkinje cell calcium responses by machine learning and ROC analysis of the performance2015

    • Author(s)
      Hoang H T, Tsutsumi S, Hashizume M, Yamashita O, Tokuda I, Sato MA, Kawato M, Kano M, Kitamura K, Toyama K
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Progranulin regulates climbing fiber synapse elimination during postnatal cerebellar development2015

    • Author(s)
      Uesaka N, Abe M, Yamazaki M, Konnno K, Mikuni T, Watanabe M, Sakimura K, Kano M
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Roles of neuroligin-2 in inhibitory synaptic transmission and climbing fiber synapse elimination in Purkinje cells during postnatal cerebellar development2015

    • Author(s)
      Lai S K, Uesaka N, Kano M
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
  • [Presentation] Multiple roles for neural activity in climbing fiber synapse elimination during postnatal cerebellar development2015

    • Author(s)
      Kano M
    • Organizer
      Cold Spring Harbor Asia (CSHA) Conference on International Brain Projects
    • Place of Presentation
      Suzhou(China)
    • Year and Date
      2015-06-21
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain2015

    • Author(s)
      Kano M
    • Organizer
      Invited Lecture at Zhejiang University, College of Pharmaceutical Sciences
    • Place of Presentation
      Zhejiang(China)
    • Year and Date
      2015-06-17
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Crucial Roles of 2-Arachidonoylglycerol Signaling in the Suppression of Epileptic Seizures2015

    • Author(s)
      Kano M
    • Organizer
      Gordon Research Conferences Cannabinoid Function in the CNS
    • Place of Presentation
      Tuscany (Italy)
    • Year and Date
      2015-05-26
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Neuronal activity and retrograde signaling that regulate synapse elimination in the developing cerebellum2015

    • Author(s)
      Kano M
    • Organizer
      Invited Lecture at Institute of Neuroscience, Technische Universität München
    • Place of Presentation
      München(Germany)
    • Year and Date
      2015-05-22
    • Description
      【発表確定】
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 自閉症感受性遺伝子を前頭前野でノックダウンしたマウスのシナプス機能異常と社会的行動の異常2015

    • Author(s)
      酒井浩旭、佐郡和人、上阪直史、狩野方伸
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-23
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 1型代謝型グルタミン酸受容体による網膜-外側膝状体シナプスの成熟型結合パタン維持2015

    • Author(s)
      鳴島円、内ケ島基政、原田武志、橋本浩一、饗場篤、渡辺雅彦、宮田麻理子、狩野方伸
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 発達期シナプス刈り込みを制御する逆行性シグナル分子の同定2015

    • Author(s)
      上阪直史、狩野方伸
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 高感度、超高速赤色カルシウムインディケーターの合理的設計による開発2015

    • Author(s)
      井上昌俊、竹内敦也、堀金慎一郎、大倉正道、玄行-安藤恵子、藤井哉、上條諭志、竹本-木村さやか、狩野方伸、中井淳一、喜多村和郎、尾藤晴彦
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 体性感覚野における経験依存的な感覚シナプス入力のクラスター化2015

    • Author(s)
      喜多村和郎、狩野方伸
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] Activity-dependent synapse elimination in developing cerebellum2015

    • Author(s)
      Kano M.
    • Organizer
      OIST Symposium “Recent findings on the cerebellar microcircuitry”
    • Place of Presentation
      沖縄科学技術大学院大学Seminar Room C210(沖縄県恩納村)
    • Year and Date
      2015-01-29
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Deficiency of glutamate transporter in astrocyte increases brain excitability and induces Tourette's Syndrome-like excessive repetitive behaviours in mice2014

    • Author(s)
      T. AIDA, J. YOSHIDA, M. NOMURA, A. TANIMURA, Y. IINO, M. SOMA, N. BAI, Y. ITO, W. CUI, H. AIZAWA, T. NAGAI, N. TAKATA, R. TAKAYANAGI, M. KANO, M. GÖTZ, H. HIRASE, K. TANAKA
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      the Walter E. Washington Convention Center(アメリカ、ワシントンDC)
    • Year and Date
      2014-11-18
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] The endocannabinoid 2-arachidonoyl glycerol suppresses seizures by decreasing excitatory synaptic input around the inner molecular layer of the dentate gyrus2014

    • Author(s)
      Y. SUGAYA, M. YAMAZAKI, K. SAKIMURA, M. KANO
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      the Walter E. Washington Convention Center(アメリカ、ワシントンDC)
    • Year and Date
      2014-11-18
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] Deficits in cerebellar plasticity and motor learning in a copy number variation mouse model of autism spectrum disorder2014

    • Author(s)
      C. PIOCHON, D.H. SIMMONS, A.D. KLOTH, G. GRASSELLI, H.K. TITLEY, H. NAKAYAMA, K. HASHIMOTO, V. WAN, T. EISSA, J. NAKATANI, A. CHERSKOV, T. MIYAZAKI, M. WATANABE, T. TAKUMI, M. KANO, S.S.H. WANG, C. HANSEL
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      the Walter E. Washington Convention Center(アメリカ、ワシントンDC)
    • Year and Date
      2014-11-16
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] Requirement of mGluRl for experience-dependent remodeling of mouse retinogeniculate synapses2014

    • Author(s)
      Kano M.
    • Organizer
      8th International Meeting on Metaborropic Glutamate Receptors
    • Place of Presentation
      Grande Alvergo Capotaormina Hotel (イタリア、タオルミナ)
    • Year and Date
      2014-09-30
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] グルタミン酸トランスポーターの欠損は過剰な繰り返し行動を引き起こすGlial glutamate transporter deficiency alteres neurotransmission, leading to excessive repetitive behaviours in mice2014

    • Author(s)
      相田知海、吉田純一、野村政壽、谷村あさみ、飯野祐介、相馬美歩、Bai Ning、伊藤亨子、Cui Wangpeng、相澤秀紀、永井てるみ、高田則雄、髙栁涼一、狩野方伸、Magdalena Götz、平瀬肇、田中光一
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-13
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 2-アラキドノイルグリセロールと関連物質によるシナプス伝達調節Modulation of synaptic transmission by 2-arachidonoylglycerol and its metabolites2014

    • Author(s)
      少作隆子、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-12
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 内因性カンナビノイド、2アラキドノイルグリセロールはCB1、CB2受容体を介して発作を抑制するThe endocannabinoid 2-arachidonoyl glycerol suppresses epileptic seizures through the activation of CBl and CB2 receptors2014

    • Author(s)
      菅谷佑樹、山崎真弥、崎村建司、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-12
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 強化学習に基づいた、サル線条体に存在する内因性エンドカンナビノイドの意志決定に関する役割The role of endocannabinoid signaling in the striatum for reinforcement learning2014

    • Author(s)
      上田康雅、岡崎哲、山中航、鮫島和行、榎本一紀、狩野方伸、木村實
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフイコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-12
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 感覚経験依存的神経回路の維持機構とその分子メカニズムMolecular mechanism of sensory experience-dependent maintenance of neuronal circuits2014

    • Author(s)
      宮田麻理子、鳴島円、内ヶ島基政、橋本浩一、原田武志、餐場篤、渡辺雅彦、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-12
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 発達期小脳シナプス刈り込みにプルキンエ細胞由来BDNFが寄与しているRetrograde BDNF signaling from Purkinje cell regulates synapse elimination in the developing cerebellum2014

    • Author(s)
      秋明貞、宮崎太輔、山崎真弥、谷村あさみ、上阪直史、渡辺雅彦、崎村健司、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフイコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-12
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] CaMKIIαとCalcineurinによる神経入力情報の非線形デコーディングNonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKII α and Calcineurin2014

    • Author(s)
      藤井哉、井上昌俊、奥野浩行、佐野慶和、竹本-木村さやか、喜多村和郎、狩野方伸、尾藤晴彦
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフイコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 新規の高感度緑色カルシウム指示薬Cal-520を用いたin vitroおよびin vivoにおける神経活動のイメージングHighly sensitive calcium imaging of neural activity in vitro and in vivo with a new fluorescent calcium indicator, Cal-5202014

    • Author(s)
      竹内敦也、多田真弓、橋爪幹、喜多村和郎、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフイコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] 網膜―外側膝状体シナプスにおける1型代謝型グルタミン酸受容体依存的なシナプス維持機構Type 1 metabotropic glutamate receptor is involved in experience-dependent maintenance of retinogeniculate synapses in the mouse visual system2014

    • Author(s)
      鳴島円、内ヶ島基政、橋本浩一、原田武志、饗場篤、渡辺雅彦、宮田麻理子、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフイコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] マウス一次視覚野におけるDiacylglycerol lipase-αの発達期可塑性への寄与Contribution of diacylglycerol lipase-α to developmental plasticity in mouse V12014

    • Author(s)
      亀山克朗、米田泰輔、後藤隆浩、寺田慧子、中西真実、崎村建司、狩野方伸、畠義郎
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] Sema3AとSema7Aによる逆行性シグナルがシナプス刈り込みを制御しているRetrograde signaling by Sema3A and Sema7A regulates synapse elimination in the developing cerebellum2014

    • Author(s)
      上阪直史、内ヶ島基政、三國貴康、中澤敬信、中尾晴美、平井宏和、饗場篤、渡辺雅彦、狩野方伸
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] IMPAIRMENT OF DEVELOPMENTAL SYNAPSE ELIMINATION IN THE CEREBELLUM OF PURKINJE CELL-SPECIFIC BDNF KNOCKOUT MICE2014

    • Author(s)
      M. Choo, T. Miyazaki, M. Yamasaki, A. Tanimura, N. Uesaka, M. Watanabe, K. Sakimura, M. Kano
    • Organizer
      9th Federation of European Neuroscience Sosieties Forum of Neuroscience
    • Place of Presentation
      MiCo Congress Centre(イタリア、ミラノ)
    • Year and Date
      2014-07-07
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] SCREENING OF RETROGRADE SIGNALING MOLECULES FOR SYNAPSE ELIMINATION IN THE DEVELOPING CEREBELLUM2014

    • Author(s)
      N. Uesaka, M. Uchigashima, T. Mikuni, T. Nakazawa, H. Hirai, M. Watanabe, M. Kano
    • Organizer
      9th Federation of European Neuroscience Sosieties Forum of Neuroscience
    • Place of Presentation
      MiCo Congress Centre(イタリア、ミラノ)
    • Year and Date
      2014-07-07
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] A THEORY TO EXPLAIN SYNAPTIC CLUSTERING IN DENDRITES2014

    • Author(s)
      R. Cazé, C. Clopath, K. Kitamura, M. Kano, S.R.
    • Organizer
      9th Federation of European Neuroscience Sosieties Forum of Neuroscience
    • Place of Presentation
      MiCo Congress Centre(イタリア、ミラノ)
    • Year and Date
      2014-07-07
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] MICROZONAL ORGANIZATION DURING SENSORIMOTOR ACTIVITIES IN RELATION TO ALDOLASE C/ZEBRIN II COMPARTMENT IN THE CEREBELLUM2014

    • Author(s)
      S. Tsutsumi, M. Yamazaki, T. Miyazaki, M. Watanabe, K. Sakimura, Y. Isomura, M. Matsuzaki, M. Kano, K. Kitamura
    • Organizer
      9th Federation of European Neuroscience Sosieties Forum of Neuroscience
    • Place of Presentation
      MiCo Congress Centre(イタリア、ミラノ)
    • Year and Date
      2014-07-07
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] MOLECULAR PATHWAY TO LONG TERM POTENTIATION AT PARALLEL FIBER TO PURKINJE SYNAPSES2014

    • Author(s)
      F. Binda, M. Kano, K. Sakimura, P. Isope
    • Organizer
      9th Federation of European Neuroscience Sosieties Forum of Neuroscience
    • Place of Presentation
      MiCo Congress Centre(イタリア、ミラノ)
    • Year and Date
      2014-07-06
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cerebellar Contribution to Brain Function From Molecules to Behavior2014

    • Author(s)
      Kano M.
    • Organizer
      6th International Congress of the Society for Research on the Cerebellum
    • Place of Presentation
      Centro Congressi Fondazione Santa Lucia IRCCS (イタリア、ローマ)
    • Year and Date
      2014-07-03
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Retrograde signaling for climbing fiber synapse elimination2014

    • Author(s)
      Kano M.
    • Organizer
      Collaborations in Neuroscience Symposium
    • Place of Presentation
      The MAX PLANCK Florida Institute for Neuroscience(アメリカ、フロリダ州ジュピター)
    • Year and Date
      2014-05-10
    • Description
      【発表確定】
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 内因性カンナビノイドは歯状回内分子層の興奮性シナプス入力を抑制し発作を軽減する2014

    • Author(s)
      菅谷佑樹, 山崎真弥, 﨑村建司, 狩野方伸
    • Organizer
      日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島県鹿児島市)
    • Year and Date
      2014-03-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] 逆行性シグナルをになう内因性カンナビノイド、2-アラキドノイルグリセロールはジアシルグリセロールリパーゼαによってオンデマンドに産生される2014

    • Author(s)
      橋本谷祐輝, 少作隆子, 狩野方伸
    • Organizer
      日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島県鹿児島市)
    • Year and Date
      2014-03-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] 発達期小脳シナプス刈り込みにプルキンエ細胞由来BDNFが寄与している2014

    • Author(s)
      秋明貞, 宮崎太輔, 山崎真弥, 谷村あさみ, 上阪直史, 渡辺雅彦, 﨑村建司, 狩野方伸
    • Organizer
      日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島県鹿児島市)
    • Year and Date
      2014-03-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] シナプス刈り込みにおける逆行性シグナルの役割2014

    • Author(s)
      上阪直史, 内ヶ島基政, 三國貴康, 平井宏和, 渡辺雅彦, 狩野方伸
    • Organizer
      日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島県鹿児島市)
    • Year and Date
      2014-03-16
    • Related Report
      2013 Annual Research Report
  • [Presentation] An autism-associated neuroligin-3 mutation impairs developmental synapse elimination in the cerebellum2013

    • Author(s)
      Lai E, Nakayama H, Nakazawa T, Tabuchi K, Hashimoto K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fine scale correspondence between the cerebellar microzones and the aldolase C compartments in mice2013

    • Author(s)
      Tsutsumi S, Yamazaki M, Sakimura K, Kitamura K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] Impairment of cerebellar microzonal organization by aberrant climbing fiber to Purkinje cell wiring in GluRδ2 (GluD2) knockout mouse2013

    • Author(s)
      Miki H, Miyazaki T, Sakimura K, Watanabe M, Kitamura K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-12
    • Related Report
      2013 Annual Research Report
  • [Presentation] Selective strengthening of single climbing fiber inputs to Purkinje cell sduring postnatal cerebellar development In vivo2013

    • Author(s)
      Kawamura Y, Nakayama H, Hashimoto K, Sakimura K, Kitamura K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-11
    • Related Report
      2013 Annual Research Report
  • [Presentation] Global sealing-down of excitatory postsynaptic responses in cerebellar Purkinje cells specifically impairs the late phase of climbing fiber synapse elimination during postnatal development2013

    • Author(s)
      Kawata S, Miyazaki T, Yamazaki M, Mikuni T, Yamasaki M, Hahimoto K, Watanabe M, Sakimura K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-11
    • Related Report
      2013 Annual Research Report
  • [Presentation] Identification of retrograde signaling molecules required for developmental synapse elimination in the cerebellum by an RNAi-based approach2013

    • Author(s)
      Uesaka N, Mikuni T, Hirai H, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego ConventionCenter (San Diego, California, アメリカ)
    • Year and Date
      2013-11-11
    • Related Report
      2013 Annual Research Report
  • [Presentation] Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineur2013

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, California, アメリカ)
    • Year and Date
      2013-11-10
    • Related Report
      2013 Annual Research Report
  • [Presentation] Postnatal desynchronization of climbing fiber responses in Purkinje cell populations of the developing cerebellum2013

    • Author(s)
      Good J-M, Miyazaki T, Kitamura T, Watanabe M, Ssakimura K, Kano M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (San Diego, Caifornia, アメリカ)
    • Year and Date
      2013-11-09
    • Related Report
      2013 Annual Research Report
  • [Presentation] マウスバレル野第2/3層におけるスパースで不均一な感覚シナプス入力分布2013

    • Author(s)
      喜多村和郎, 狩野方伸
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] サルにおける瞬目反射条件づけ : 筋電位測定法と高速イメージング法を用いた瞬目反射条件づけ方法の開発とその評価2013

    • Author(s)
      桐野豊, 山本茂幸, 鈴木一隆, 豊田晴義, 狩野方伸, 塚田秀夫
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Endocannnabinoid-Mediated Modulation of Inhibitory Synaptic Transmission to GABAergic and non-GABAergic Neurons in the Bed Nucleus of the Stria Terminal is (BNST)2013

    • Author(s)
      Kato A, Yanagawa Y, Kano M
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-21
    • Related Report
      2013 Annual Research Report
  • [Presentation] stargazin (TARP γ-2)の欠損による小脳プルキンエ細胞でのカルシウムシグナルの減弱により登上繊維刈り込みの後期過程が選択的に障害される2013

    • Author(s)
      川田慎也, 橋本浩一, 三國貴康, 山崎真弥, 宮崎太輔, 山崎美和子, 渡辺雅彦, 﨑村建司, 狩野方伸
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-21
    • Related Report
      2013 Annual Research Report
  • [Presentation] 内因性カンナビノイド2アラキドノイルグリセロールは歯状回の興奮性シナプス伝達を抑制し発作を抑制する2013

    • Author(s)
      菅谷佑樹, 山崎真弥, 﨑村建司, 狩野方伸
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-21
    • Related Report
      2013 Annual Research Report
  • [Presentation] マウス小脳皮質におけるaldolase C発現領域に相関した同期生の高い登上繊維応答2013

    • Author(s)
      堤新一郎, 多田真弓, 崎村建司, 喜多村和郎, 狩野方伸
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] モノアシルグリセロールリパーゼ欠損マウスにおける海馬依存症記憶機能の包括的評価2013

    • Author(s)
      岸本泰司, Barbara Cagniard, 山崎真弥, 中山順子, 﨑村建司, 桐野豊, 狩野方伸
    • Organizer
      日本神経科学大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-20
    • Related Report
      2013 Annual Research Report

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Published: 2013-06-20   Modified: 2022-04-28  

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