| Budget Amount *help |
¥125,710,000 (Direct Cost: ¥96,700,000、Indirect Cost: ¥29,010,000)
Fiscal Year 2017: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2016: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
Fiscal Year 2015: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2014: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2013: ¥67,860,000 (Direct Cost: ¥52,200,000、Indirect Cost: ¥15,660,000)
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| Outline of Final Research Achievements |
Information processing in the brain is achieved via interactions between many areas. To understand the overall picture of interactions between multiple areas and further elucidate the neural circuits underlying such interactions at synapse level, we achieved the following three goals. (1) We developed a method of wide-field calcium imaging and functional mapping of the entire mouse cortex. We elucidated the functional differentiation of nine higher visual areas. (2) We developed a method to simultaneously monitor the neural activity and hemodynamic signal from the entire mouse cortex. We revealed that functional connectivity of hemodynamic signals, which is often used in psychiatric studies in human fMRI, is indeed derived from functional connectivity in neural activity. (3) We developed a method to visualize information transmitted between areas at synapse level. We revealed what information is transmitted from thalamus to primary visual cortex (V1), and V1 to higher visual areas.
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