| Budget Amount *help |
¥215,280,000 (Direct Cost: ¥165,600,000、Indirect Cost: ¥49,680,000)
Fiscal Year 2017: ¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2016: ¥42,900,000 (Direct Cost: ¥33,000,000、Indirect Cost: ¥9,900,000)
Fiscal Year 2015: ¥44,460,000 (Direct Cost: ¥34,200,000、Indirect Cost: ¥10,260,000)
Fiscal Year 2014: ¥41,080,000 (Direct Cost: ¥31,600,000、Indirect Cost: ¥9,480,000)
Fiscal Year 2013: ¥42,900,000 (Direct Cost: ¥33,000,000、Indirect Cost: ¥9,900,000)
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| Outline of Final Research Achievements |
There is an urgent need for the supply of reliable drugs for treatment of cancer and dementia in Japan. In this research, biologically important natural products are taken up in order to seek for a seed for drug development. The purpose is to establish a novel and robust synthetic pathway for total synthesis of natural products, which allows their structural modification to synthesize a more potent and selective drug candidate. Efficient synthetic pathways were successfully established and they were applied for preparation of the analogues.
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