Molecular Communication: Design, Modelling and Experiments

• Project/Area Number: 25240011
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Information network
• Research Institution: Osaka University
• Principal Investigator: NAKANO Tadashi 大阪大学, 生命機能研究科, 招へい准教授 (70571173)
• Project Period (FY): 2013-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥36,270,000 (Direct Cost: ¥27,900,000、Indirect Cost: ¥8,370,000); Fiscal Year 2016: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000); Fiscal Year 2015: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000); Fiscal Year 2014: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000); Fiscal Year 2013: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
• Keywords: 分子通信 / 情報ネットワーク / ネットワーク応用 / 情報通信工学 / センサネットワーク / バイオテクノロジー / ナノテクノロジー / バイオＩＣＴ / バイオICT

Outline of Final Research Achievements

Molecular communication is an emerging communication paradigm for bio-nanomachines that is inspired by how biological cells in nature communicate. In this project, we aimed to establish molecular communication as a communication technology, and conducted range of research to address physical layer issues to application designs in molecular communication. We first developed a reference architecture of molecular communication with a set of communication protocols. We then developed mathematical models and computer simulation models to analyze the performance of molecular communication systems. We further designed an application of molecular communication, and investigated its behavior using an integrated approach of computer simulations and wet-laboratory experiments.

Research Products

• [Int'l Joint Research] ヨーク大学(カナダ)
• [Int'l Joint Research] 電子科技大学(中国)
• [Int'l Joint Research] 国際台湾大学(台湾)
• [Int'l Joint Research] ヨーク大学(カナダ)
• [Journal Article] A mathematical model of non-diffusion-based mobile molecular communication networks (2017)
  • Author(s): S. Iwasaki, J. Yang, and T. Nakano
  • Journal Title: IEEE Communications Letters Volume: 印刷中 Issue: 9 Pages: 1969-1972
  • DOI: 10.1109/lcomm.2017.2681061
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Design and wet-laboratory implementation of reliable end-to-end molecular communication (2017)
  • Author(s): T. Furubayashi, Y. Sakatani, T. Nakano, A. Eckford, and N. Ichihashi
  • Journal Title: Wireless Networks Volume: 印刷中 Issue: 5 Pages: 1809-1819
  • DOI: 10.1007/s11276-016-1435-4
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Performance Evaluation of Leader-follower-based Mobile Molecular Communication Networks for Target Detection Applications. (2016)
  • Author(s): Nakano T, Okaie Y, Kobayashi S, Koujin T, Chan C-H, Hsu Y-H, Okaie Y, Obuchi T, Hara T, Hiraoka Y, Haraguchi T
  • Journal Title: IEEE Transactions on Communications Volume: 65-2 Issue: 2 Pages: 663-676
  • DOI: 10.1109/tcomm.2016.2628037
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Packet Fragmentation and Reassembly in Molecular Communication (2016)
  • Author(s): T. Furubayashi, T. Nakano, A. Eckford, Y. Okaie, and T. Yomo
  • Journal Title: IEEE Transactions on Nanobioscience Volume: 未定 Issue: 3 Pages: 284-288
  • DOI: 10.1109/tnb.2016.2526051
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Externally Controllable Molecular Communication (2014)
  • Author(s): Tadashi Nakano, Shouhei Kobayashi, Tatsuya Suda, Yutaka Okaie, Yasushi Hiraoka, Tokuko Haraguchi
  • Journal Title: IEEE Journal of Selected Areas in Communications Volume: 32 Issue: 12 Pages: 2417-2431
  • DOI: 10.1109/jsac.2014.2367667
  • Peer Reviewed / Open Access
• [Journal Article] Cooperative Target Tracking by a Mobile Bionanosensor Network (2014)
  • Author(s): Okaie Y, Nakano T, Hara T, Obuchi T, Hosoda K, Hiraoka Y, Nishio S.
  • Journal Title: IEEE Transactions on Nanobioscience Volume: 13 Issue: 3 Pages: 267-277
  • DOI: 10.1109/tnb.2014.2343237
  • Peer Reviewed
• [Journal Article] Autonomous Mobile Bionanosensor Networks for Target Tracking: A Two-dimensional Model (2014)
  • Author(s): Y. Okaie, T. Nakano, T. Hara, and S. Nishio
  • Journal Title: Nano Communication Networks Volume: 5 Issue: 3 Pages: 63-71
  • DOI: 10.1016/j.nancom.2014.05.003
  • Peer Reviewed
• [Journal Article] Molecular Communication among Biological Nanomachines: A Layered Architecture and Research Issues (2014)
  • Author(s): T. Nakano, T. Suda, Y. Okaie, M. J. Moore, and A. V. Vasilakos
  • Journal Title: IEEE Transactions on Nanobioscience Volume: 13 Issue: 3 Pages: 169-197
  • DOI: 10.1109/tnb.2014.2316674
  • Peer Reviewed / Open Access
• [Journal Article] TCP-like Molecular Communications (2014)
  • Author(s): L. Felicetti, M. Femminella, G. Reali, T. Nakano, and A. V. Vasilakos
  • Journal Title: IEEE Journal of Selected Areas of Communication (JSAC) Volume: 32 Issue: 12 Pages: 2354-2367
  • DOI: 10.1109/jsac.2014.2367653
  • Peer Reviewed
• [Presentation] Rna as a nanoscale data transmission medium: Error analysis (2017)
  • Author(s): A. W. Eckford, T. Furubayashi, and T. Nakano
  • Organizer: 16th International Conference on Nanotechnology (IEEE NANO 2016)
  • Place of Presentation: 仙台国際センター（宮城県仙台市）
  • Year and Date: 2017-08-22
  • Int'l Joint Research
• [Presentation] Channel switching in molecular communication networks through calcium signaling (2017)
  • Author(s): P. He, T. Nakano, Y. Mao, Q. Liu, and K. Yang
  • Organizer: IEEE Wireless Communications and Networking Conference 2017 (IEEE WCNC 2017)
  • Place of Presentation: Hyatt Regency San Francisco（サンフランシスコ・アメリカ）
  • Year and Date: 2017-03-19
  • Int'l Joint Research
• [Presentation] Impacts of erasure coding on robustness against molecular packet losses in aqueous, collisional environments (2017)
  • Author(s): H. Egashira, J. Suzuki, J. S. Mitzman, T. Nakano, and H. Fukuda
  • Organizer: 10th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2017)
  • Place of Presentation: スティーブンス工科大学（ホーボーケン・アメリカ）
  • Int'l Joint Research
• [Presentation] Leader-follower Based Target Detection Model for Mobile Molecular Communication Networks (2016)
  • Author(s): T. Nakano, S. Kobayashi, T. Koujin, C.-H. Chan, Y.-H. Hsu, Y. Okaie, T. Obuchi, T. Hara, Y. Hiraoka, and T. Haraguchi
  • Organizer: 17th IEEE International workshop on Signal Processing Advances in Wireless Communications (SPAWC 2016)
  • Place of Presentation: エディンバラ（イギリス）
  • Year and Date: 2016-07-03
  • Int'l Joint Research
• [Presentation] Research challenges in bionanosensor networks (2016)
  • Author(s): Y. Okaie, T. Nakano, T. Obuchi, and T. Hara
  • Organizer: IEEE International Conference on Computer Communications Workshops
  • Place of Presentation: Hyatt Regency San Francisco（サンフランシスコ・アメリカ）
  • Year and Date: 2016-04-10
  • Int'l Joint Research
• [Presentation] Research Challenges in Bionanosensor Networks (2016)
  • Author(s): Y. Okaie, T. Nakano, T. Obuchi, and T. Hara
  • Organizer: IEEE International Conference on Computer Communications (IEEE INFOCOM 2016)
  • Place of Presentation: サンフランシスコ（アメリカ）
  • Year and Date: 2016-04-10
  • Int'l Joint Research
• [Presentation] Non-diffusion-based Molecular Communication Using Adhesive Molecules (2016)
  • Author(s): T. Obuchi, T. Nakano, Y. Okaie, and T. Hara
  • Organizer: 2016 IEICE General Conference
  • Place of Presentation: 九州大学（福岡県福岡市）
  • Year and Date: 2016-03-15
• [Presentation] Leader-follower based target detection model for mobile molecular communication networks (2016)
  • Author(s): T. Nakano, S. Kobayashi, T. Koujin, C.-H. Chan, Y.-H. Hsu, Y. Okaie, T. Obuchi, T. Hara, Y. Hiraoka, and T. Haraguchi
  • Organizer: 17th IEEE International workshop on Signal Processing Advances in Wireless Communications
  • Place of Presentation: エジンバラ大学（エジンバラ・イギリス）
  • Int'l Joint Research
• [Presentation] Reliable End-to-end Molecular Communication with Packet Replication and Retransmission (2015)
  • Author(s): T. Furubayashi, T. Nakano, A. Eckford, and T. Yomo
  • Organizer: IEEE Global Communications Conference (Globecom 2015)
  • Place of Presentation: サンディエゴ（アメリカ）
  • Year and Date: 2015-12-06
  • Int'l Joint Research
• [Presentation] Molecular Communication through Biological Pattern Formation (2015)
  • Author(s): T. Nakano, T. Suda, and M. Moore
  • Organizer: IEEE Global Communications Conference (Globecom 2015)
  • Place of Presentation: サンディエゴ（アメリカ）
  • Year and Date: 2015-12-06
  • Int'l Joint Research
• [Presentation] Packet Replication and Noise in Reliable End-to-end Molecular Communication (2015)
  • Author(s): T. Furubayashi, T. Nakano, A. Eckford, N. Ichihashi, and T. Yomo
  • Organizer: International Conference on Bio-inspired Information and Communications Technologies (BICT 2015)
  • Place of Presentation: ニューヨーク（アメリカ）
  • Year and Date: 2015-12-03
  • Int'l Joint Research
• [Presentation] Mobility and Controllability of Bio-nanomachines (2015)
  • Author(s): Y. Okaie, T. Nakano, T. Obuchi, T. Hara, and S. Nisiho
  • Organizer: International Conference on Bio-inspired Information and Communications Technologies (BICT 2015)
  • Place of Presentation: ニューヨーク（アメリカ）
  • Year and Date: 2015-12-03
  • Int'l Joint Research
• [Presentation] A Feedback-based Molecular Communication Protocol for Noisy Intrabody Environments (2015)
  • Author(s): J. Mitzman, B. Morgan, T. O Soro, J. Suzuki, and T. Nakano
  • Organizer: IEEE Healthcom 2015
  • Place of Presentation: ボストン（アメリカ）
  • Year and Date: 2015-10-14
  • Int'l Joint Research
• [Presentation] Inbody Mobile Bionanosensor Networks Through Non-diffusion-based Molecular Communication (2015)
  • Author(s): T. Obuchi, Y. Okaie, T. Nakano, T. Hara, and S. Nishio
  • Organizer: IEEE International Conference on Communications (ICC 2015)
  • Place of Presentation: ロンドン（イギリス）
  • Year and Date: 2015-06-08
  • Int'l Joint Research
• [Presentation] Molecular Communication for Inbody Mobile Bionanosensor Networks (2014)
  • Author(s): T. Nakano
  • Organizer: Brain-inspired Information Communication Technologies Workshop (BIICT 2014)
  • Place of Presentation: ボストン（米国）
  • Year and Date: 2014-12-03
  • Int'l Joint Research / Invited
• [Presentation] Bacterium-based Mobile Bionanosensor Networks for Target Tracking: A Biologically Realistic Model (2014)
  • Author(s): Y. Okaie, T. Nakano, T. Obuchi, T. Hara, and S. Nishio
  • Organizer: International Conference on Bio-inspired Information and Communications Technologies (BICT 2014)
  • Place of Presentation: ボストン（米国）
  • Year and Date: 2014-12-01
  • Int'l Joint Research
• [Presentation] Mobile Bionanosensor Networks Through Molecular Communication (2014)
  • Author(s): T. Nakano, T. Hara, Y. Okaie, T. Obuchi, and S. Nishio
  • Organizer: Asia-Pacific Microwave Conference 2014 (APMC 2014)
  • Place of Presentation: 仙台国際センター（宮城県仙台市）
  • Year and Date: 2014-11-04
  • Int'l Joint Research / Invited
• [Presentation] Modeling and Performance Evaluation of Mobile Bionanosensor Networks for Target Tracking (2014)
  • Author(s): Y. Okaie, T. Nakano, T. Hara, K. Hosoda, Y. Hiraoka, and S. Nishio
  • Organizer: IEEE International Conference on Communications 2014 (ICC 2014)
  • Place of Presentation: シドニー（オーストラリア）
  • Year and Date: 2014-06-10
  • Int'l Joint Research
• [Presentation] Externally Controllable Molecular Communication Systems for Pattern Formation (2014)
  • Author(s): T. Nakano, S. Kobayashi, T. Suda, Y. Okaie, Y. Hiraoka, and T. Haraguchi
  • Organizer: ACM International Conference on Nanoscale Computing and Communication (NANOCOM 2014)
  • Place of Presentation: アトランタ（米国）
  • Year and Date: 2014-05-13
  • Int'l Joint Research
• [Presentation] A Biologically-inspired Intrabody Nanonetwork: Design Considerations (2013)
  • Author(s): T. Nakano, K. Hosoda, Y. Nakamura, and K. Ishii
  • Organizer: 8th International Conference on Body Area Networks (BODYNETS)
  • Place of Presentation: Boston, USA
  • Year and Date: 2013-09-30 – 2013-10-02
• [Presentation] Addressing by Concentrations of Receptor Saturation in Bacterial Communication (2013)
  • Author(s): M. Moore and T. Nakano
  • Organizer: 8th International Conference on Body Area Networks (BODYNETS)
  • Place of Presentation: Boston, USA
  • Year and Date: 2013-09-30 – 2013-10-02
• [Presentation] Single Target Tracking in Bionanosensor Networks: Preliminary Simulation Results (2013)
  • Author(s): Y. Okaie, T. Nakano, T. Hara, and S. Nishio
  • Organizer: 8th International Conference on Body Area Networks (BODYNETS)
  • Place of Presentation: Boston, USA
  • Year and Date: 2013-09-30 – 2013-10-02
• [Presentation] Molecular Communication and Networking (2013)
  • Author(s): T. Nakano
  • Organizer: 8th International Conference on Body Area Networks (BODYNETS)
  • Place of Presentation: Boston, USA
  • Year and Date: 2013-09-30 – 2013-10-02
  • Invited
• [Presentation] Cooperative Drug Delivery through Molecular Communication among Biological Nanomachines (2013)
  • Author(s): T. Nakano, M. J. Moore, Y. Okaie, A. Enomoto, and T. Suda
  • Organizer: International Workshop on Molecular and Nanoscale Communications (MoNaCom)
  • Place of Presentation: Budapest, Hungary
  • Year and Date: 2013-07-09
• [Remarks] 大阪大学大学院生命機能研究科 分子通信工学研究室
  • URL: http://www.fbs.osaka-u.ac.jp/labs/tadashi_nakano/index.html