| Budget Amount *help |
¥46,670,000 (Direct Cost: ¥35,900,000、Indirect Cost: ¥10,770,000)
Fiscal Year 2017: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2016: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2015: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2014: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2013: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
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| Outline of Final Research Achievements |
Executive function is an important function of the prefrontal cortex. The prefrontal cortex is known to produce top-down control signals to achieve executive functions. By these signals, the prefrontal cortex controls a variety of cognitive operations including memory retrieval and decision-making. However, the nature of this signal is not well known. In the present study, we analyzed prefrontal activities while monkeys performed a pair-association task in which monkeys needed to retrieve a paired stimulus and a free-choice decision-making task in which monkeys needed to select either one of two targets. In the latter task, whichever target they selected, they obtained the same reward. We found that stimulus-selective response and delay-period activity must be a candidate of the control signal in the memory-retrieval task and that the magnitude of spontaneous activity occurred before target presentation affects eventual target selection in free-choice decision-making.
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