| Project/Area Number |
25242050
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Kyoto Institute of Technology |
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Principal Investigator |
Gen Syokyu 京都工芸繊維大学, 繊維科学センター, 教授 (90283655)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMURA Kazuaki 北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 准教授 (00432328)
AKATANI Akiko 兵庫医科大学, 医学部, 助教授 (50212402)
YOSHIDA Yoshiko 富山大学, 大学院医学薬学研究部, 准教授 (00171421)
OKABE Motonori 富山大学, 大学院医学薬学研究部, 助教 (60283066)
山本 芙樹 京都工芸繊維大学, 繊維科学センター, 研究員 (50753787)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥47,190,000 (Direct Cost: ¥36,300,000、Indirect Cost: ¥10,890,000)
Fiscal Year 2015: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2014: ¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2013: ¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
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| Keywords | 凍結保存 / ガラス化保存 / 緩慢凍結 / 組織 / 細胞 / 受精卵 / 不凍ポリアミノ酸 / 新規凍結方法 / 幹細胞凍結保存 / 受精卵凍結保存 / 新規凍結保護剤 / 細胞シート凍結保存 / 幹細胞バンク / 再生医療 / 不妊治療 / 細胞凍結保護高分子 / 細胞シート / 受精卵保存用デバイス |
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| Outline of Final Research Achievements |
Currently, certain realization is expected about regenerative medicine. However, research of them is not concentrated on so much by the technology of preserving tissue currently, in order to focus on creating reproduction tissue material. Then, we performed the research and development of the novel cryopreservation technology of various tissues. In development of new cryopreservation, It found out the possibility of the "new vitrification freeze method of preservation." In addition, we obtained the result which produces the result more than fixed in preservation of a fertilized ovum, umbilical cord blood, etc., and leads to future. Furthermore, in preservation of a cell sheet, it proved that new cryopreservation liquid has the preservation capability more than equivalent as compared with the conventional method. It was shown that the new cryopreservation liquid which solves toxic problems, such as dimethylsulfoxide used conventionally, has the possibility to clinical application.
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