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Physics of development from molecular assembly to protocell

Research Project

Project/Area Number 25247070
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Biological physics/Chemical physics/Soft matter physics
Research InstitutionTohoku University

Principal Investigator

Imai Masayuki  東北大学, 理学(系)研究科(研究院), 教授 (60251485)

Co-Investigator(Kenkyū-buntansha) SAKUMA Yuka  東北大学, 大学院理学研究科, 助教 (40630801)
URAKAMI Naohito  山口大学, 理工学研究科, 准教授 (50314795)
SUZUKI Kentaro  神奈川大学, 理学部, 外部資金雇用研究者 (60512324)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥42,900,000 (Direct Cost: ¥33,000,000、Indirect Cost: ¥9,900,000)
Fiscal Year 2015: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2014: ¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
Fiscal Year 2013: ¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Keywordsプロトセル / ベシクル / 化学刺激 / 膜分子合成 / 分子シミュレーション
Outline of Final Research Achievements

in this research we have investigated vesicle dynamics triggered by chemical stimuli, which might be the first step of the evolution from vesicles to cellular life. By applying chemical stimuli, vesicles show unique dynamics, such as migration, deformations, relevant to biological functions. We revealed that chemical modifications of the surface tension and molecular cross section are responsible for the observed vesicle dynamics. In addition we succeeded to synthesize a new artificial lipid precursor molecule, which is hydrolyzed to produce the membrane molecule at the membrane surface. The membrane molecules are incorporated into the vesicle membrane and causes the vesicle growth.The growing vesicle produces offspring vesicles by division. The vesicle division process was investigated by a molecular dynamics simulation. the simulation revealed that the coupling of molecular shape and vesicle shape plays an important role in the vesicle division.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (109 results)

All 2016 2015 2014 2013 Other

All Int'l Joint Research (4 results) Journal Article (13 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 12 results,  Acknowledgement Compliant: 5 results,  Open Access: 1 results) Presentation (80 results) (of which Int'l Joint Research: 15 results,  Invited: 19 results) Book (2 results) Remarks (10 results)

  • [Int'l Joint Research] University of Southern Denmark(デンマーク)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] University Paris Diderot Paris 7/University Pierre & Marie Curie Paris 6(フランス)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] University of Ljubljana/Jozef Stefan Institute(スロベニア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ETH(スイス)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Migration of phospholipid vesicles in response to OH2016

    • Author(s)
      Atsuji Kodama, Yuka Sakuma, Masayuki Imai, Yutaka Oya, Toshihiro Kawakatsu, Nicolas Puff and Miglena I. Angelova
    • Journal Title

      Soft Matter

      Volume: 12 Issue: 11 Pages: 2877-2886

    • DOI

      10.1039/c5sm02220g

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Role of Inverse-Cone-Shape Lipids in Temperature-Controlled Self-Reproduction of Binary Vesicles2016

    • Author(s)
      T. Jimbo, Y. Sakuma, N. Urakami, P. Ziherl, and M. Imai
    • Journal Title

      Biophys. J.

      Volume: 110 Issue: 7 Pages: 1551-1562

    • DOI

      10.1016/j.bpj.2016.02.028

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Dynamics of fatty acid vesicles in response to pH stimuli2015

    • Author(s)
      Keita Ikari, Yuka Sakuma, Takehiro Jimbo, Atsuji Kodama, Masayuki Imai, Pierre-Alain Monnard and Steen Rasmussen
    • Journal Title

      Soft Matter

      Volume: 11 Issue: 31 Pages: 6327-6334

    • DOI

      10.1039/c5sm01248a

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A Recursive Vesicle-based Model Protocell with a Primitive Model Cell Cycle2015

    • Author(s)
      Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi Sugawara
    • Journal Title

      Nature Commun.

      Volume: 6 Issue: 1

    • DOI

      10.1038/ncomms9352

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Shape transformations of toroidal vesicles2015

    • Author(s)
      H. Noguchi, A. Sakashita and M. Imai
    • Journal Title

      Soft Matter

      Volume: 11 Issue: 1 Pages: 193-201

    • DOI

      10.1039/c4sm01890g

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] From Vesicles to Protocells: The Roles of Amphiphilic Molecules2015

    • Author(s)
      Y. Sakuma and M. Imai
    • Journal Title

      Life

      Volume: 5 Issue: 1 Pages: 651-675

    • DOI

      10.3390/life5010651

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Morphological variation of a lipid vesicle confined in a spherical vesicle2014

    • Author(s)
      Ai Sakashita, Masayuki Imai, and Hiroshi Noguchi
    • Journal Title

      Physical Review E

      Volume: 89 Issue: 4

    • DOI

      10.1103/physreve.89.040701

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular dynamics simulation for shape change of water-in-oil droplets2014

    • Author(s)
      N. Urakami, A. Takaki, Masayuki Imai and Takashi Yamamoto
    • Journal Title

      Molecular Simulation

      Volume: - Issue: 10-12 Pages: 1-7

    • DOI

      10.1080/08927022.2014.931582

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Magnetic Manipulation of Nucleic Acid Base Microcrystals for DNA Sensing2014

    • Author(s)
      Y. Mizukawa, K. Suzuki, S. Yamamura, Y. Sugawara, T. Sugawara, M. Iwasaka
    • Journal Title

      IEEE Transactions on Magnetics

      Volume: 50 Issue: 11 Pages: 1-4

    • DOI

      10.1109/tmag.2014.2328633

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自らが増殖する人工細胞の化学構築2014

    • Author(s)
      菅原正, 鈴木健太郎
    • Journal Title

      高分子

      Volume: 63 Pages: 382-384

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Spontaneous transformation from micelles to vesicles associated with sequential conversions of comprising amphiphiles within assemblies2014

    • Author(s)
      K. Takakura, T. Yamamoto, K. Kurihara, T. Toyota, K. Ohnuma and T. Sugawara
    • Journal Title

      Chem. Commun.

      Volume: 50 Issue: 82 Pages: 2190-2192

    • DOI

      10.1039/c3cc43488e

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tubular membrane formation of binary giant unilamellar vesicles composed of cylinder and inverse-cone shaped lipids2013

    • Author(s)
      Y. Sakuma, T. Taniguchi, T. Kawakatsu M. Imai
    • Journal Title

      The Biophysical Journal

      Volume: 105 Issue: 9 Pages: 2074-2081

    • DOI

      10.1016/j.bpj.2013.09.021

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bi-axial alignment control of guanine crystals by diamagnetic orientation2013

    • Author(s)
      M. Iwasaka, Y. Miyashita, Y. Mizukawa, K. Suzuki, T. Toyota, T. Sugawara
    • Journal Title

      Appl. Phys. Exp

      Volume: 6 Issue: 3 Pages: 0370021-4

    • DOI

      10.7567/apex.6.037002

    • NAID

      10031159857

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 界面活性剤溶液中における紐状分子集合体の自己駆動現象2016

    • Author(s)
      諸橋博昭・豊田太郎・今井正幸
    • Organizer
      日本物理学会第71回年次大会
    • Place of Presentation
      東北学院大学, 宮城県仙台市
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化学刺激によるベシクル膜面上での孔形成2016

    • Author(s)
      佐久間由香・兒玉篤治・今井正幸
    • Organizer
      日本物理学会第71回年次大会
    • Place of Presentation
      東北学院大学, 宮城県仙台市
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] 接着したベシクルの形態形成2016

    • Author(s)
      河野拓馬・海老原隆太・佐久間由香・今井正幸・Primoz Ziherl
    • Organizer
      日本物理学会第71回年次大会
    • Place of Presentation
      東北学院大学, 宮城県仙台市
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] ベシクルの分裂シミュレーション2016

    • Author(s)
      浦上直人・今井正幸
    • Organizer
      日本物理学会第71回年次大会
    • Place of Presentation
      東北学院大学, 宮城県仙台市
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化学刺激に誘起される分子集合体の自己駆動現象2015

    • Author(s)
      諸橋博昭・今井正幸・豊田太郎
    • Organizer
      第5回ソフトマター研究会
    • Place of Presentation
      東北大学, 宮城県仙台市
    • Year and Date
      2015-12-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 多細胞モデルの形態形成2015

    • Author(s)
      河野拓馬・海老原隆太・佐久間由香・今井正幸・Primoz Ziherl
    • Organizer
      第5回ソフトマター研究会, 東北大学, 2015年12月17~19日
    • Place of Presentation
      東北大学, 宮城県仙台市
    • Year and Date
      2015-12-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 二価の陽イオンによるリン脂質ベシクルの駆動2015

    • Author(s)
      兒玉 篤治、佐久間 由香、今井 正幸、川勝 年洋、NicolasPuff、 Miglena I. Angelova
    • Organizer
      第5回ソフトマター研究会
    • Place of Presentation
      東北大学, 宮城県仙台市
    • Year and Date
      2015-12-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] ベシクルの分裂に関する分子動力学シミュレーション2015

    • Author(s)
      浦上直人、今井正幸
    • Organizer
      第5回ソフトマター研究会
    • Place of Presentation
      東北大学, 宮城県仙台市
    • Year and Date
      2015-12-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] Self-reproduction of giant vesicle emerged under non-equilibrium condition2015

    • Author(s)
      Tadashi Sugawara, Katsuto Takakura, Kensuke Kurihara, Taro Toyota, and Kentaro Suzuki
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Positive phototaxis of oil-droplets of caged oleic acid against an anisotropic UV irradiation2015

    • Author(s)
      Kentaro Suzuki, Naoyuki Nakayama, and Tadashi Sugawara
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Giant vesicle containing a photo-sensitive smaller giant vesicle2015

    • Author(s)
      Kotaro Machida, Kentaro Suzuki, Kazuo Yamaguchi, and Tadashi Sugawara
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Morphorogical diversity of giant vesicle-based protcell depending on degree of complexation of DNA and catalysts2015

    • Author(s)
      Muneyuki Matsuo, Kensuke Kurihara, Taro Toyota, and Tadashi Sugawara
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Self-driven motion of oil-droplet emerged after chemical reaction2015

    • Author(s)
      Kentaro Suzuki, Naoyuki Nakayama, and Tadashi Sugawara
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ベシクルからプロトセルへの道:ソフトマターからのアプローチ2015

    • Author(s)
      今井正幸
    • Organizer
      山田研究会「生物と非生物をつなぐ」
    • Place of Presentation
      ラフォーレ修善寺, 静岡県伊豆市
    • Year and Date
      2015-11-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 二重ベシクルの紫外線照射による光応答性内部ベシクルからの内包物の放出2015

    • Author(s)
      町田巧太郎, 鈴木健太郎, 山口和夫, 菅原正
    • Organizer
      第26回基礎有機化学連合討論会
    • Place of Presentation
      愛媛大学, 愛媛県松山市
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] 光分解反応と連動したo/wエマルション中の油滴の駆動現象2015

    • Author(s)
      鈴木健太郎, 中山直之, 山口和夫, 菅原正
    • Organizer
      第26回基礎有機化学連合討論会
    • Place of Presentation
      愛媛大学, 愛媛県松山市
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Chemical control of vesicle dynamics2015

    • Author(s)
      M. Imai
    • Organizer
      iCeMS International Symposium
    • Place of Presentation
      Kyoto university, Kyoto, Kyoto, Japan
    • Year and Date
      2015-09-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 光分解反応に連動した自己駆動油滴ダイナミクス2015

    • Author(s)
      鈴木健太郎, 中山直之, 菅原正
    • Organizer
      第9回分子科学討論会
    • Place of Presentation
      東京工業大学, 東京都目黒区
    • Year and Date
      2015-09-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化学刺激によるリン脂質ベシクルの駆動2015

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 大矢豊大, 川勝年洋, Nicolas Puff, Miglena I. Angelova
    • Organizer
      日本物理学会2015年秋大会
    • Place of Presentation
      関西大学, 大阪府吹田市
    • Year and Date
      2015-09-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] Approach to Minimal Cell based on membrane physics2015

    • Author(s)
      Y. Sakuma
    • Organizer
      International Workshop on Challenge to Synthesizing Life
    • Place of Presentation
      Hotel Kagetsuen, Hakone, Kanagawa, Japan
    • Year and Date
      2015-08-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Physics of self-reproduction of vesicle reveal by 3D analysis2015

    • Author(s)
      T. Jimbo
    • Organizer
      International Workshop on Challenge to Synthesizing Life
    • Place of Presentation
      Hotel Kagetsuen, Hakone, Kanagawa, Japan
    • Year and Date
      2015-08-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Molecular simulations of shape changes of vesicles2015

    • Author(s)
      Naohito Urakami
    • Organizer
      International Workshop on Challenge to Synthesizing Life
    • Place of Presentation
      Hotel Kagetsuen, Hakone, Kanagawa, Japan
    • Year and Date
      2015-08-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Spontaneous Motion of Photo-active Oil Droplets2015

    • Author(s)
      Kentaro Suzuki
    • Organizer
      International Workshop on Challenging to Synthesizing Life
    • Place of Presentation
      Hotel Kagetsuen, Hakone, Kanagawa, Japan
    • Year and Date
      2015-08-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Migration of phospholipid vesicles in response to chemical stimuli2015

    • Author(s)
      A. Kodama, Y. Sakuma, M. Imai, Y. Oya, T. Kawakatsu, N. Puff and M. Angelova
    • Organizer
      International Symposium on Fluctuation and Structure out of Equilibrium 2015
    • Place of Presentation
      Kyoto university, Kyoto, Kyoto, Japan
    • Year and Date
      2015-08-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A key for self-reproduction of vesicles2015

    • Author(s)
      T. Jimbo, Y. Sakuma, P. Ziherl, N. Urakami, and M. Imai
    • Organizer
      International Symposium on Fluctuation and Structure out of Equilibrium 2015, (2015. 8. 20-23)
    • Place of Presentation
      Kyoto university, Kyoto, Kyoto, Japan
    • Year and Date
      2015-08-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Sustainability of Recursive Vesicle-based Protocell2015

    • Author(s)
      Tadashi Sugawara, Kensuke Kurihara, Muneyuki Matsuo, Taro Toyota, and Kentaro Suzuki
    • Organizer
      International Symposium on Fluctuation and Structure out of Equilibrium 2015
    • Place of Presentation
      Kyoto university, Kyoto, Kyoto, Japan
    • Year and Date
      2015-08-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Construction of Photo-sensitive GV in GV2015

    • Author(s)
      Kentaro Suzuki, Kotaro Machida, Kazuo Yamaguchi, and Tadashi Sugawara
    • Organizer
      International Symposium on Fluctuation and Structure out of Equilibrium 2015
    • Place of Presentation
      Kyoto university, Kyoto, Kyoto, Japan
    • Year and Date
      2015-08-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ベシクルの多様な形状変化過程とメカニズムの解析2015

    • Author(s)
      大藤義之、浦上直人、今井正幸、山本隆
    • Organizer
      第64回高分子学会年次大会
    • Place of Presentation
      札幌コンベンションセンター, 北海道札幌市
    • Year and Date
      2015-05-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Recursive Vesicle-based Protocell Constructed as a Molecular System2015

    • Author(s)
      Tadashi Sugawara, Kensuke Kurihara, Muneyuki Matsuo, Taro Toyota, and Kentaro Suzuki
    • Organizer
      SysChem 2015
    • Place of Presentation
      Kerkrade, Netherland
    • Year and Date
      2015-05-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 界面活性剤の刺激により駆動するリン脂質凝集体2015

    • Author(s)
      諸橋博昭・豊田太郎・今井正幸
    • Organizer
      新学術領域研究「ゆらぎと構造の協奏」第2回公開シンポジウム
    • Place of Presentation
      東京大学, 東京都文京区
    • Year and Date
      2015-05-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化学反応に遅れて出現する自己駆動油滴ダイナミクス2015

    • Author(s)
      鈴木 健太郎, 菅原 正
    • Organizer
      揺らぎと構造の協奏:第2回公開シンポジウム
    • Place of Presentation
      東京大学, 東京都文京区
    • Year and Date
      2015-05-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 運動開始に遅れのある紫外線応答性油滴の自己駆動系2015

    • Author(s)
      鈴木 健太郎, 中山 直之, 菅原 正
    • Organizer
      機能性物性融合科学研究会シリーズ2 ソフトダイナミクス
    • Place of Presentation
      物性研究所, 千葉県柏市
    • Year and Date
      2015-04-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] DNA添加によるカチオン性ベシクル表面状態の変化2015

    • Author(s)
      亀田恵介・廣石達也・鈴木健太郎・菅原正
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学、千葉
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 紫外線応答型二重ベシクル2015

    • Author(s)
      町田巧太郎・伊藤愼弥・中島拓磨・鈴木健太郎・山口和夫・菅原正
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学、千葉
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] How Self-proliferative Vesicle-based Protocell Acquire Responsibility and Recursibility2015

    • Author(s)
      T. Sugawara, K. Kurihara, K. Suzuki, T. Toyota, M. Matsuo
    • Organizer
      BIT's 1st Annual World Congress of Smart Material-2015
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2015-03-23 – 2015-03-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 変形を伴うリン脂質分子集合体の自己駆動現象2015

    • Author(s)
      諸橋博昭・豊田太郎・今井正幸
    • Organizer
      日本物理学会第70回年次大会
    • Place of Presentation
      早稲田大学、東京
    • Year and Date
      2015-03-21 – 2015-03-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 化学作用に対する膜の応答ダイナミクス2015

    • Author(s)
      今井正幸
    • Organizer
      公開シンポジウム「ソフトマターを基盤とするバイオ系の構築」
    • Place of Presentation
      首都大学東京、東京
    • Year and Date
      2015-03-19
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 分子レベルの外場応答が導くマクロ集合体のモルフォロジー2015

    • Author(s)
      鈴木健太郎
    • Organizer
      第一回 ミクロとマクロをつなぐ次世代科学
    • Place of Presentation
      神奈川大学、神奈川
    • Year and Date
      2015-03-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] リン脂質ベシクルの化学駆動2015

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 川勝年洋, Nicolas Puff, Miglena I. Angelova
    • Organizer
      新学術領域「ゆらぎと構造の協奏」研究会「アクティブ・マター研究の過去・現在・未来」
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2015-03-14 – 2015-03-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] リン脂質分子集合体の自己駆動現象2015

    • Author(s)
      諸橋博昭・豊田太郎・今井正幸
    • Organizer
      新学術領域「ゆらぎと構造の協奏」研究会「アクティブ・マター研究の過去・現在・未来」
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2015-03-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 分子が探る水和水の構造とダイナミクス2015

    • Author(s)
      菅原正, 鈴木健太郎
    • Organizer
      新世代研究所主催 水和ナノ構造研究会
    • Place of Presentation
      新世代研究所、東京
    • Year and Date
      2015-03-12
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 化学刺激に誘起される分子集合体の自己駆動2015

    • Author(s)
      諸橋博昭・豊田太郎・今井正幸
    • Organizer
      第8回東北大学理学研究科6専攻合同シンポジウム
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2015-02-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 三次元画像解析による二成分ベシクル自己生産機構の研究2015

    • Author(s)
      神保岳大, 佐久間由香, Primoz Ziherl, 今井正幸
    • Organizer
      第4回ソフトマター研究会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2015-01-06 – 2015-01-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] リン脂質ベシクルの化学駆動とそれに伴う変形と破裂2015

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 川勝年洋, Nicolas Puff, Miglena I. Angelova
    • Organizer
      第4回ソフトマター研究会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2015-01-06 – 2015-01-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] 多細胞系モデルの形態変化2015

    • Author(s)
      河野拓馬, 佐久間由香, 今井正幸, Primoz Ziherl
    • Organizer
      第4回ソフトマター研究会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2015-01-06 – 2015-01-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] ソフトな粒子の結晶化とガラス形成におけるスローダイナミクス2015

    • Author(s)
      原田朋佳 今井正幸
    • Organizer
      第4回ソフトマター研究会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2015-01-06 – 2015-01-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] ベシクルの形状変化メカニズムの解析2015

    • Author(s)
      大藤義之・浦上直人・今井正幸・山本隆
    • Organizer
      第4回ソフトマター研究会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2015-01-06 – 2015-01-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] How could a model protocell acquire identity as life through autonomous responses towards external stimuli?2014

    • Author(s)
      T. Sugawara, K. Kurihara, M. Matsuo, T. Toyota, K. Suzuki
    • Organizer
      4th Symposium on Artificial Life and Biomimetic Functional Materials
    • Place of Presentation
      University of Tokyo, Tokyo
    • Year and Date
      2014-11-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Self-driven motion of oil droplets launched by UV irradiation2014

    • Author(s)
      K. Suzuki, N. Nakayama, T. Sugawara
    • Organizer
      4th Symposium on Artificial Life and Biomimetic Functional Materials
    • Place of Presentation
      University of Tokyo, Tokyo
    • Year and Date
      2014-11-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 散逸粒子動力学法によるベシクルの形状変化メカニズムの解析2014

    • Author(s)
      大藤義之・浦上直人・今井正幸・山本隆
    • Organizer
      第29回中国四国地区高分子若手研究会
    • Place of Presentation
      サンポートホール高松、高松
    • Year and Date
      2014-10-30 – 2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 散逸粒子動力学法によるベシクルの形状変化2014

    • Author(s)
      大藤義之・浦上直人・今井正幸・山本隆
    • Organizer
      第63回高分子討論会
    • Place of Presentation
      長崎大学、長崎
    • Year and Date
      2014-09-24 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] ケージドオレイン酸油滴に見られる特異な自発運動ダイナミクス2014

    • Author(s)
      鈴木健太郎・中山直之・菅原正
    • Organizer
      第8回 分子科学討論会
    • Place of Presentation
      広島大学、東広島
    • Year and Date
      2014-09-21 – 2014-09-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 紫外線応答型ベシクルを目指した珪藻土吸着法によるリン脂質合成2014

    • Author(s)
      町田巧太郎・伊藤愼弥・中島拓磨・鈴木健太郎・菅原正
    • Organizer
      第25回 基礎有機化学討論会
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2014-09-07 – 2014-09-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] 分子集合体からプロトセルに向けて2014

    • Author(s)
      今井正幸
    • Organizer
      新学術領域「ゆらぎと構造の協奏」第2回領域研究会
    • Place of Presentation
      北海道大学、札幌
    • Year and Date
      2014-08-29 – 2014-08-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] ベシクルの自己生産の三次元画像解析2014

    • Author(s)
      神保岳大, 佐久間由香, Primoz Ziherl, 今井正幸
    • Organizer
      新学術領域「ゆらぎと構造の協奏」第2回領域研究会
    • Place of Presentation
      北海道大学、札幌
    • Year and Date
      2014-08-29 – 2014-08-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 化学刺激に対するイオン性リン脂質の振る舞い2014

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 川勝年洋
    • Organizer
      新学術領域「ゆらぎと構造の協奏」第2回領域研究会
    • Place of Presentation
      北海道大学、札幌
    • Year and Date
      2014-08-29 – 2014-08-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] Physical background of self-reproduction of vesicles2014

    • Author(s)
      T. Jimbo, Y. Sakuma, P. Ziherl, and M. Imai
    • Organizer
      Open Questions on the Origin of Life 2014
    • Place of Presentation
      International Institute for Advanced Studies, Kyoto
    • Year and Date
      2014-07-12 – 2014-07-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] How Prebiotic Materials Collaborate in a Vesicle-based Protocell2014

    • Author(s)
      T. Sugawara, M. Matsuo, K. Kurihara, T. Toyota, K. Suzuki
    • Organizer
      OQOL2014, Open Questions on the Origin of Life 2014
    • Place of Presentation
      International Institute for Advanced Studies, Kyoto
    • Year and Date
      2014-07-12 – 2014-07-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] Constructive Approach towards a Vesicle-based Protcell2014

    • Author(s)
      T. Sugawara, M. Matsuo, K. Kurihara, T. Toyota, K. Suzuki
    • Organizer
      Origins2014, 2nd ISSOL – The International Astrobiology Society and Bioastronomy (IAU C51) Joint International Conference
    • Place of Presentation
      Nara-ken New Public Hall, Nara
    • Year and Date
      2014-07-06 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 散逸粒子動力学シミュレーションによるベシクルの形状変化メカニズム2014

    • Author(s)
      大藤義之・浦上直人・今井正幸・山本隆
    • Organizer
      第63回高分子学会年次大会
    • Place of Presentation
      名古屋大学、名古屋
    • Year and Date
      2014-05-28 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] ベシクルからプロトセルへのアプローチ2014

    • Author(s)
      佐久間由香・今井正幸
    • Organizer
      日本膜学会第36回年会
    • Place of Presentation
      早稲田大学、東京
    • Year and Date
      2014-05-12 – 2014-05-13
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] From vesicle to protocell

    • Author(s)
      Y. Sakuma and M. Imai
    • Organizer
      245th ACS National Meeting
    • Place of Presentation
      New Orleans, LA, USA
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Chemophoresis of Neutral Phospholipid Vesicle

    • Author(s)
      A. Kodama, Y. Sakuma, M. Imai, T. Kawakatsu, N. Puff, and M. I. Angelova
    • Organizer
      International Workshop “From Soft Matter to Protocell”
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Binary Lipid Vesicles Having Functions of Protocell

    • Author(s)
      Y. Sakuma, T. Jimbo and M. Imai
    • Organizer
      International Workshop “From Soft Matter to Protocell”
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Chemophoresis of Vesicle

    • Author(s)
      A. Kodama, Y. Sakuma, M. Imai, T. Kawakatsu, N. Puff and M. I. Angelova
    • Organizer
      Workshop on Cross Correlation & Transport Phenomena in Soft Matter
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecular dynamics simulation for shape change of water-in-oil droplets

    • Author(s)
      N. Urakami, A. Takaki, M. Imai, T. Yamamoto
    • Organizer
      3rd International Conference on Molecular Simulation
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dissipative Particle Dynamics Simulation of shape changes of vesicle

    • Author(s)
      Y. Oofuji, N. Urakami, T. Yamamoto
    • Organizer
      The International Conference on Artificial Life and Robotics 2014
    • Place of Presentation
      Ohita, Japan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Morphological Change of Giant Vesicle Caused nu Molecule-based Dynamics

    • Author(s)
      K. Suzuki
    • Organizer
      The 9th International Symposium on the Kanagawa University-National Taiwan University Exchange Program 2013
    • Place of Presentation
      Kanagawa, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Drastic deformation of phospholipid vesicles coupled with chemophoresis

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 川勝年洋
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島
    • Related Report
      2013 Annual Research Report
  • [Presentation] 自発曲率と相分離の結合によるベシクルのチューブ構造形成

    • Author(s)
      佐久間 由香,谷口 貴志,川勝 年洋,今井 正幸
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島
    • Related Report
      2013 Annual Research Report
  • [Presentation] ベシクルの自己生産の三次元画像解析

    • Author(s)
      神保岳大, 佐久間由香, 浦上直人, Primoz Ziherl, 今井正幸
    • Organizer
      日本物理学会2013年秋季大会
    • Place of Presentation
      徳島
    • Related Report
      2013 Annual Research Report
  • [Presentation] リン脂質ベシクルの化学駆動

    • Author(s)
      兒玉篤治, 佐久間由香, 今井正幸, 川勝年洋
    • Organizer
      第3回ソフトマター研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] ベシクルの自己生産の三次元画像解析

    • Author(s)
      神保岳大, 佐久間由香, 浦上直人, Primoz Ziherl, 今井正幸
    • Organizer
      第3回ソフトマター研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] ベシクルの自己生産の三次元画像解析

    • Author(s)
      神保岳大, 佐久間由香, 浦上直人, Primoz Ziherl, 今井正幸
    • Organizer
      日本物理学会第69回年次大会
    • Place of Presentation
      神奈川
    • Related Report
      2013 Annual Research Report
  • [Presentation] 油中水滴型ドロップレットの形状変化メカニズム

    • Author(s)
      浦上直人、高木 彬生、今井 正幸、山本 隆
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
  • [Presentation] 余剰面積と面積差に関するベシクルの形状変化

    • Author(s)
      大藤 義之、浦上 直人、今井 正幸、山本 隆
    • Organizer
      第3回ソフトマター研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] カルボン酸とイミダゾリウムを有する双性イオン型両親媒性分子によるジャイアントベシクル形成

    • Author(s)
      大倉優作, 栗原顕輔, 豊田太郎, 高倉克人, 景山義之, 鈴木健太郎, 菅原正
    • Organizer
      第24回基礎有機化学討論会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] ビオローゲン型分子ワイヤーで連結した金ナノ粒子ネットワークにおける電子輸送

    • Author(s)
      尾又清登, 豊田太郎, 松下未知雄, 鈴木健太郎, 菅原正
    • Organizer
      第7回分子科学討論会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
  • [Presentation] カルボキシレート基とイミダゾリウム基を有する双性イオン型両親媒性分子によるジャイアントベシクル形成とその膜表面電荷のpH依存性

    • Author(s)
      大倉優作、栗原顕輔、豊田太郎、高倉克人、景山義之、鈴木健太郎、菅原正
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Annual Research Report
  • [Presentation] 紫外線照射によって運動を開始する自己駆動油滴

    • Author(s)
      鈴木健太郎, 菅原正
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋
    • Related Report
      2013 Annual Research Report
  • [Book] Biomembrane as a Soft Matter2015

    • Author(s)
      Yuka Sakuma and Masayuki Imai
    • Total Pages
      8
    • Publisher
      Springer-Verlag
    • Related Report
      2014 Annual Research Report
  • [Book] 生体膜の分子機構 -リピッドワールドが先導する生命科学2014

    • Author(s)
      佐久間由香、今井正幸
    • Total Pages
      34
    • Publisher
      化学同人
    • Related Report
      2014 Annual Research Report
  • [Remarks] 東北大学理学研究科物理学専攻 ソフトマター・生物物理研究室

    • URL

      http://www.bio.phys.tohoku.ac.jp

    • Related Report
      2015 Annual Research Report
  • [Remarks] 山口大学理工学部生体分子シミュレーション研究室

    • URL

      http://mms.sci.yamaguchi-u.ac.jp/index.html

    • Related Report
      2015 Annual Research Report
  • [Remarks] 神奈川大学理学部化学科菅原研究室

    • URL

      http://www.chem.kanagawa-u.ac.jp/~sugawara/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 東北大学理学研究科物理学専攻ソフトマター・生物物理研究室

    • URL

      http://www.bio.phys.tohoku.ac.jp/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 山口大学理工学研究科生体分子シミュレーション研究室

    • URL

      http://mms.sci.yamaguchi-u.ac.jp/~urakami/index.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] 神流川大学理学部化学科菅原研究室

    • URL

      http://www.chem.kanagawa-u.ac.jp/~sugawara/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 化学者 鈴木健太郎のページ

    • URL

      http://suzukiscientia.web.fc2.com

    • Related Report
      2014 Annual Research Report
  • [Remarks] ソフトマター・生物物理研究室 東北大学理学研究科物理学専攻

    • URL

      http://www.bio.phys.tohoku.ac.jp/

    • Related Report
      2013 Annual Research Report
  • [Remarks] Sugawara group / Kanagawa University

    • URL

      http://www.chem.kanagawa-u.ac.jp/~sugawara/

    • Related Report
      2013 Annual Research Report
  • [Remarks] suzukiScientia

    • URL

      http://suzukiscientia.web.fc2.com

    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-15   Modified: 2019-07-29  

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