| Budget Amount *help |
¥35,750,000 (Direct Cost: ¥27,500,000、Indirect Cost: ¥8,250,000)
Fiscal Year 2015: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2014: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000)
Fiscal Year 2013: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
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| Outline of Final Research Achievements |
The purpose of this study is to enhance analysis-chip technologies based on paper material to allow us to reduce manufacturing cost and environmental load caused by medical wastes. We were aiming at developing a detection method for small amount of sample on a paper analysis chip and prototyping an automatic analysis system in order to envision problems and propose solutions towards practical use. Consequently, a micro detection cell for an absorptiometry with thermal lens effect and thin gold electrodes (t=100~150nm) for an alternating current impedance measurement (10kHz) were designed and fabricated on paper chips. They allowed us to measure an absorbance (644nm) of trace amount of sample (~1uL) and signal related to electrolyte (Na＋) in the sample. In addition, we prototyped an automatic analysis system with including newly developed detectors, reagent dispensers, paper-chip precision positining mechanism etc. This system successfully demonstrated cooperative automatic operation.
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