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Cortical oscillations dependent on pyramidal cell subtypes

Research Project

Project/Area Number 25250005
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurophysiology / General neuroscience
Research InstitutionNational Institute for Physiological Sciences

Principal Investigator

Kawaguchi Yasuo  生理学研究所, 基盤神経科学研究領域, 教授 (40169694)

Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥45,110,000 (Direct Cost: ¥34,700,000、Indirect Cost: ¥10,410,000)
Fiscal Year 2017: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2016: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2015: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords前頭皮質 / ガンマ振動 / 錐体細胞 / 橋核投射細胞 / 交叉性線条体投射細胞 / FS細胞 / パルブアルブミン / 線条体投射細胞 / 皮質間投射 / シナプス結合 / 視床 / 振動現象 / スパイン / 大脳皮質 / 振動 / 非錐体細胞 / 対側線条体投射細胞 / GABA作動性FS細胞 / 視床入力 / 新皮質 / 発火様式 / 電場電位
Outline of Final Research Achievements

The integrative function of frontal cortex may rely on the synchronous firing of diverse neurons during oscillations. Fast-spiking (FS) cells, a subtype of inhibitory neurons, and thalamocortical inputs are supposed to play important roles in oscillation induction. For further understanding of cooperative activities among frontal cortical neurons, we analyzed thalamic inputs, synaptic connections with FS cells, and firing phases during oscillations in individual cortical cell subtypes. Consequently, we found cell subtype differences in thalamocortical inputs and firing phases during slow and gamma waves. Combined with local connection analysis, these findings suggest that individual FS cells do not selectively inhibit specific output subnetworks, but could synchronize diverse subcortical and corticocortical output channels in an integrative way.

Academic Significance and Societal Importance of the Research Achievements

脳は機能・局所回路が異なる多様な領域からできている。その中でも大脳皮質の前頭野は多くの皮質領野へ興奮性出力を送ることで、これらの活動を統合する役割を担うと考えられている。そのために、前頭野のパルブアルブミンという蛋白質を発現する抑制性細胞が局所回路接続と発火特性を特化させ、多様な投射パターンを持つ錐体細胞を制御し、出力信号の適切な組み合わせを正確なタイミングで他領域に送り出す可能性が高いことを本研究で見出した。

Report

(6 results)
  • 2018 Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (94 results)

All 2018 2017 2016 2015 2014 2013 Other

All Int'l Joint Research (3 results) Journal Article (14 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 13 results,  Open Access: 8 results,  Acknowledgement Compliant: 2 results) Presentation (74 results) (of which Int'l Joint Research: 19 results,  Invited: 15 results) Book (1 results) Remarks (2 results)

  • [Int'l Joint Research] マックスプランク研究所(ドイツ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Institute of Neuroscience and Medicine(Germany)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] South Valley University(Egypt)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] A carbon nanotube tape for serial-section electron microscopy of brain ultrastructure2018

    • Author(s)
      Kubota Y, Sohn J, Hatada S, Schurr M, StraehleJ, Gour A, Neujahr R, MikiT, Mikula S, Kawaguchi Y
    • Journal Title

      Nat. Commun.

      Volume: 9 Issue: 1 Pages: 437-437

    • DOI

      10.1038/s41467-017-02768-7

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Segregated Excitatory?Inhibitory Recurrent Subnetworks in Layer 5 of the Rat Frontal Cortex2017

    • Author(s)
      Morishima Mieko、Kobayashi Kenta、Kato Shigeki、Kobayashi Kazuto、Kawaguchi Yasuo
    • Journal Title

      Cerebral Cortex

      Volume: 27 Issue: 12 Pages: 5846-5857

    • DOI

      10.1093/cercor/bhx276

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pyramidal cell subtypes and their synaptic connections in layer 5 of rat frontal cortex2017

    • Author(s)
      Kawaguchi Y
    • Journal Title

      Cereb Cortex

      Volume: 27 Issue: 12 Pages: 5755-5771

    • DOI

      10.1093/cercor/bhx252

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 大脳皮質局所回路:古典的競合選択モデルの実験的検証と混合選択性細胞2017

    • Author(s)
      森田賢治, 川口泰雄
    • Journal Title

      生体の科学

      Volume: 68 Pages: 43-47

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Cortical divergent projections in mice originate from two sequentially generated, distinct populations of excitatory cortical neurons with different initial axonal outgrowth characteristics2016

    • Author(s)
      Hatanaka Y, Namikawa T, Yamauchi K, Kawaguchi Y
    • Journal Title

      Cereb Cortex

      Volume: 26 Pages: 2257-2270

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Selective thalamic innervation of rat frontal cortical neurons.2016

    • Author(s)
      Shigematsu N, Ueta Y, Mohamed AA, Hatada S, Fukuda T, Kubota Y, Kawaguchi, Y
    • Journal Title

      Cerebral Cortex

      Volume: 26 Issue: 6 Pages: 2689-2701

    • DOI

      10.1093/cercor/bhv124

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Functional effects of distinct innervation styles of pyramidal cells by fast spiking cortical interneurons2015

    • Author(s)
      Kubota Y, Kondo S, Nomura M, Hatada S, Yamaguchi N, Mohamed AA, Karube F, Luebke J, Kawaguchi Y
    • Journal Title

      eLife

      Volume: 4

    • DOI

      10.7554/elife.07919

    • NAID

      120005997706

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Computing reward prediction error: an integrated account of cortical timing and basal-ganglia pathways for appetitive and aversive learning2015

    • Author(s)
      Morita K, Kawaguchi Y
    • Journal Title

      Eur J Neurosci

      Volume: 42 Issue: 4 Pages: 2003-2021

    • DOI

      10.1111/ejn.12994

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Temporal structure of neuronal activity among cortical neuron subtypes during slow oscillations in anesthetized rats2015

    • Author(s)
      Ushimaru M, Kawaguchi Y
    • Journal Title

      J Neurosci

      Volume: 35 Issue: 34 Pages: 11988-12001

    • DOI

      10.1523/jneurosci.5074-14.2015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multiple layer 5 pyramidal cell subtypes relay cortical feedback from secondary to primary motor areas in rats.2013

    • Author(s)
      植田 禎史
    • Journal Title

      Cerebral Cortex

      Volume: - Issue: 9 Pages: 1-15

    • DOI

      10.1093/cercor/bht088

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dopaminergic control of motivation and reinforcement learning: a closed-circuit account for reward-oriented behavior2013

    • Author(s)
      Kenji Morita, Mieko Morishima, Katsuyuki Sakai, Yasuo Kawaguchi
    • Journal Title

      The Journal of Neuroscience

      Volume: 33 Issue: 20 Pages: 8866-8890

    • DOI

      10.1523/jneurosci.4614-12.2013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional Significance of Rall's Power of Three Halves Law in Cortical Nonpyramidal Cells2013

    • Author(s)
      Yoshiyuki Kubota
    • Journal Title

      Advances in Cognitive Neurodynamics (III)

      Volume: XVI Pages: 45-51

    • DOI

      10.1007/978-94-007-4792-0_7

    • ISBN
      9789400747913, 9789400747920
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common excitatory inputs to electrically connected cortical fast-spiking cell networks.2013

    • Author(s)
      大塚 岳,川口 泰雄
    • Journal Title

      Journal of Neurophysiology

      Volume: 110 Issue: 4 Pages: 795-806

    • DOI

      10.1152/jn.00071.2013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direction- and distance-dependent interareal connectivity of pyramidal cell subpopulations in the rat frontal cortex.2013

    • Author(s)
      植田 禎史,平井 康治,大塚 岳,川口 泰雄
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 11 Pages: 164-164

    • DOI

      10.3389/fncir.2013.00164

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Local recurrent subnetworks correlated with long-distance projections in frontal cortex2018

    • Author(s)
      Kawaguchi Y
    • Organizer
      International symposium on Brain Information Dynamics 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Ipsilateral and contralateral corticocortical projection-dependent subcircuits in layer 2/3 of rat frontal cortex2018

    • Author(s)
      Ueta Y, Kawaguchi Y
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Dynamics of thalamocortical activities during motor execution and learning2018

    • Author(s)
      Tanaka YH, Tanaka YR, Kondo M, Terada S, Kawaguchi Y, Matsuzaki M
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ATUMtome 用の新開発テープと高解像画像用組織処理法2017

    • Author(s)
      窪田芳之、孫在隣、畑田小百合、川口泰雄
    • Organizer
      第73回日本顕微鏡学会学術講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Differential involvement of direct- and indirect-pathway spiny projection neurons in action valuation and update in the dorsomedial striatum2017

    • Author(s)
      Kimura M, Nonomura S, Nishizawa K, Kobayashi K, Sakai Y, Kawaguchi Y, Nambu A, Yamanaka K, Isomura Y
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A novel tape for ATUMtome and high resolution electron microscopy2017

    • Author(s)
      Kubota Y, Sohn J, Hatada S, Kawaguchi Y
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Labeling of neurons derived from intermediate neuronal progenitors in the mouse cerebral cortex2017

    • Author(s)
      Hatanaka Y, Hirata T, Kawaguchi Y
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Cortical pyramidal cell-subtype dependent motor learning and oscillatory activities2017

    • Author(s)
      Otsuka T, Kawaguchi Y
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Thalamocortical dynamics mediate learning and execution of self-initiated movement2017

    • Author(s)
      Tanaka YH, Tanaka YR, Hira R, Kondo M, Terada S, Kawaguchi Y, Matsuzaki M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Activity of direct- and indirect-pathway striatal projection neurons identified by optogenetics during adaptive choice task with probabilistic reward2017

    • Author(s)
      Nonomura S, Yamanaka K, Nishizawa K, Kobayashi K, Sakai Y, Kawaguchi Y, Nambu A, Isomura Y, Kimura M
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Pyramidal cell subtype-dependent inhibitory innervations in layer 5 of the rat frontal cortex2017

    • Author(s)
      Morishima M, Kawaguchi Y
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 前頭皮質のニューロン構成と標準回路2017

    • Author(s)
      川口泰雄
    • Organizer
      新学術領域研究「脳情報動態を規定する多領野連関と並列処理(脳情報動態)」特別講演会「コネクトミクスからAIへ」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Action-specific reinforcement and update by direct- and indirect- pathway striatal projection neurons2017

    • Author(s)
      Nonomura S, Nishizawa K, Kobayashi K, Sakai Y, Kawaguchi Y, Nambu A, Yamanaka K, Enomoto K, Isomura Y, Kimura M
    • Organizer
      47th annual meeting of the Society for Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A conductive novel tape material and a new staining protocol for volume electron microscopy applications2017

    • Author(s)
      Kubota Y, Sohn J, Hatada S, Schurr M, Straehle J, Gour A.G, Neujahr R, Mikula S, Kawaguchi Y
    • Organizer
      47th annual meeting of the Society for Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Innervation differences of layer 5a and 5b Martinotti cells in frontal cortex2017

    • Author(s)
      Kawaguchi Y, Morishima M
    • Organizer
      47th annual meeting of the Society for Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 前頭皮質ニューロンと再帰的結合の多様性2017

    • Author(s)
      川口泰雄
    • Organizer
      次世代脳プロジェクト冬のシンポジウム2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 前頭皮質における錐体細胞と抑制スタイルの多様性2017

    • Author(s)
      川口泰雄
    • Organizer
      第12回日本統合失調症学会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Synapse density and estimated number on various neurons of the rat frontal cortex2017

    • Author(s)
      Kubota Y,Sekigawa A,Mohamed AA,Kondo S,Karube F,Tanaka Y,Kawaguchi Y
    • Organizer
      第94回日本生理学会大会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Pyramidal cell diversity and inhibition styles in the frontal cortex2016

    • Author(s)
      Kawaguchi Y,Morishima M
    • Organizer
      International Symposium on Adaptive Circuit Shift 2016
    • Place of Presentation
      同志社大学(京都府京都市)
    • Year and Date
      2016-03-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Plexin A2/A4 - Semaphorin 6A signaling is involved in termination of migration for uppermost layer neurons in the mouse cerebral cortex2016

    • Author(s)
      Hatanaka Y,Kawasaki T,Hirata T,Kawaguchi Y
    • Organizer
      International Symposium on Adaptive Circuit Shift 2016
    • Place of Presentation
      同志社大学(京都府京都市)
    • Year and Date
      2016-03-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synapses from fast-spiking GABAergic neurons are tuned to specific postsynaptic target domains.2016

    • Author(s)
      Kawaguchi Y,Kubota Y
    • Organizer
      新学術領域「大脳新皮質構築」終了公開国際シンポジウム
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-02-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] PlexinA2/A4 signaling is necessary for proper termination of migration for uppermost part of layers 2/3 neurons in the mouse cerebral cortex2016

    • Author(s)
      Hatanaka Y,Kawasaki T,Hirata T,Kawaguchi Y
    • Organizer
      新学術領域「大脳新皮質構築」終了公開国際シンポジウム
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-02-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] An excitatory and inhibitory synapse density on various neurons in the rat frontal cortex2016

    • Author(s)
      Kubota Y,Sekigawa A,Mohamed AA,Kondo S,Karube F,Tanaka Y,Kawaguchi Y
    • Organizer
      EMBO Dendrites 2016 meeting
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] GABAergic inputs to spine of striatal medium spiny neuron2016

    • Author(s)
      Kubota Y,Kawaguchi Y
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] Proper termination of migration for uppermost part of layers 2/3 neurons requires PlexinA2/A4-Semaphorin6A signaling in the mouse cerebral cortex2016

    • Author(s)
      Hatanaka Y,Kawasaki T,Kawaguchi Y,Hirata T
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] Corticocortical cell diversity in superficial layers of the rat frontal cortex2016

    • Author(s)
      Ueta Y,Hirai Y, Kawaguchi Y
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] Distinct thalamocortical inputs mediate learning and execution of self-initiated movement2016

    • Author(s)
      Tanaka YH,Tanaka YR,Hira R,KondoM,Terada S,Kawaguchi Y,Matsuzaki M
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] Activity of dopamine D2 receptor-expressing striatal neurons during decision-making task2016

    • Author(s)
      Nonomura S,Yamanaka K,Nishizawa K,Kobayashi K,Sakai Y,Kawaguchi Y,Nambu A,Isomura Y,Kimura M
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] Interaction between GABAergic cells and two types of target-specific pyramidal cells in layer 5 of the rat frontal cortex2016

    • Author(s)
      Morishima M,Kawaguchi Y
    • Organizer
      第39回日本神経科学大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] GABAergic/non-GABAergic synaptic inputs to striatal medium spiny neurons2016

    • Author(s)
      Kubota Y,Kawaguchi Y
    • Organizer
      46th annual meeting of the Society for Neuroscience
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Layer 5 GABAergic Circuits in the Frontal Cortex2016

    • Author(s)
      Kawaguchi Y
    • Organizer
      The 7th International Neural Microcircuit Conference- Recent advances in the analysis of cortical microcircuits-
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Oscillatory Activities in the Cortical Networks2016

    • Author(s)
      Otsuka T,Kawaguchi Y
    • Organizer
      The 7th International Neural Microcircuit Conference- Recent advances in the analysis of cortical microcircuits-
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Interaction between GABAergic cells and two types of target-specific pyramidal cells in layer 5 of the rat frontal cortex2016

    • Author(s)
      Morishima M,Kawaguchi Y
    • Organizer
      The 7th International Neural Microcircuit Conference- Recent advances in the analysis of cortical microcircuits-
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Conserved dimensions of dendritic trees in cortical pyramidal cell2016

    • Author(s)
      Mohamed AA,Yamaguchi N,Hatada S,Luebke J,Kawaguchi Y,Kubota Y
    • Organizer
      The 7th International Neural Microcircuit Conference- Recent advances in the analysis of cortical microcircuits-
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大脳皮質パルブアルブミン細胞の歴史と謎2015

    • Author(s)
      川口泰雄
    • Organizer
      生理研研究会「行動システム脳科学の新展開」
    • Place of Presentation
      生理学研究所(愛知県岡崎市)
    • Year and Date
      2015-12-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] An excitatory and inhibitory synapse density on various nonpyramidal cells in the rat cerebral cortex2015

    • Author(s)
      Kubota Y,Sekigawa A,Hatada S,Kawaguchi Y
    • Organizer
      The 2nd East-Asia Microscopy Conference
    • Place of Presentation
      The Himeji Chamber of Commerce and Industry(Himeji, Hyogo)
    • Year and Date
      2015-11-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Temporal organization of pyramidal neuron output to the striatum2015

    • Author(s)
      Kawaguchi Y
    • Organizer
      International Symposium on Prediction and Decision Making 2015
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2015-10-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Functional effects of distinct innervation styles of pyramidal cells by fast spiking cortical interneurons2015

    • Author(s)
      Kubota Y,Kondo S,Nomura M,Hatada S,Yamaguchi N,Mohamed AA,Karube F,Luebke J,Kawaguchi Y
    • Organizer
      45th annual meeting of the Society for Neuroscience
    • Place of Presentation
      McCormick Place(Chicago, USA)
    • Year and Date
      2015-10-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multi-compartmental models of corticopontine- and crossed corticostriatal neurons of rat frontal cortex2015

    • Author(s)
      Kondo M,Morishima M,Kawaguchi Y,Morita K
    • Organizer
      11th Bernstein Conference 2015
    • Place of Presentation
      Neue Universitaet(Heidelberg, Germany)
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Correlative light and electron microscopy of brain tissue using two-photon microscope and FIB/SEM2015

    • Author(s)
      Kubota Y,Villa KL,Berry KP,Subramanian J,Cha JW,So PT,Nedivi E,Kawaguchi Y
    • Organizer
      Microscopy & Microanalysis 2015
    • Place of Presentation
      Oregon Convention Center(Portland, USA)
    • Year and Date
      2015-08-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 徐波振動における前頭皮質ニューロンの発火時系列2015

    • Author(s)
      牛丸弥香、川口泰雄
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Interaction between two types of pyramidal cells and GABAergic cells in the layer 5 of the frontal cortex2015

    • Author(s)
      森島美絵子、川口泰雄
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Conserved morphology of dendritic trees in cortical pyramidal cell2015

    • Author(s)
      Mohamed AA,Kubota Y,Kondo S,Yamaguchi N,Hatada S,Nomura M,Younes HA,Tanaka YR,Abdalla KEH,Luebke J,Kawaguchi Y
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 大脳領域間結合と局所回路網の統合的解析2015

    • Author(s)
      川口泰雄
    • Organizer
      CREST '脳神経回路の形成・動作原理の解明と制御技術の創出' 研究領域 第2回公開シンポジウム '脳神経回路研究の最前線2015'
    • Place of Presentation
      JST東京本部別館 (東京都千代田区)
    • Year and Date
      2015-02-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] Conserved dimensional properties of dendritic trees in cortical pyramidal cell2014

    • Author(s)
      Kubota Y, Mohamed AA, Yamaguchi N, Hatada S, Luebke J, Kawaguchi Y
    • Organizer
      44th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Walter E. Washington Convention Center (Washington DC, USA)
    • Year and Date
      2014-11-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cortical membrane oscillatory activities induced by light stimulations2014

    • Author(s)
      Otsuka T, Kawaguchi Y
    • Organizer
      44th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Walter E. Washington Convention Center (Washington DC, USA)
    • Year and Date
      2014-11-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大脳皮質錐体細胞の樹状突起の形態解析2014

    • Author(s)
      窪田芳之, Mohamed AA, 根東覚, 野村真樹, 畑田小百合, 山口登, 川口泰雄
    • Organizer
      第10回IIRSセミナー
    • Place of Presentation
      東京大学 (東京都文京区)
    • Year and Date
      2014-11-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] Temporal structure of activities in cortical neuron subtypes during slow oscillations2014

    • Author(s)
      Ushimaru M, Kawaguchi Y
    • Organizer
      4th Joint CIN-NIPS Symposium
    • Place of Presentation
      University of Tuebingen (Tuebingen, Germany)
    • Year and Date
      2014-10-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] Conserved dimensional properties of dendritic trees in cortical pyramidal cell2014

    • Author(s)
      Mohamed AA, Yamaguchi N, Hatada S, Luebke J , Kawaguchi Y, Kubota Y
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 自発運動時における視床から大脳皮質第1層への入力パターン2014

    • Author(s)
      田中康代, 田中康裕, 和氣弘明, 正水芳人, 川口泰雄, 松崎政紀
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 光刺激によって誘発される皮質回路におけるオシレーション活動2014

    • Author(s)
      大塚岳, 川口泰雄
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Oscillatory activities evoked by light stimulations in cortical circuits2014

    • Author(s)
      Otsuka T, Kawaguchi Y
    • Organizer
      NIPS International Workshop and Satellite Symposium of Neuroscience 2014
    • Place of Presentation
      生理学研究所 (愛知県岡崎市)
    • Year and Date
      2014-09-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Conserved dimensional properties of dendritic trees in cortical pyramidal cell2014

    • Author(s)
      Mohamed AA, Yamaguchi N, Hatada S, Luebke J, Kawaguchi Y, Kubota Y
    • Organizer
      NIPS International Workshop and Satellite Symposium of Neuroscience 2014
    • Place of Presentation
      生理学研究所 (愛知県岡崎市)
    • Year and Date
      2014-09-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cortical pyramidal cell subtypes and connection specificity2013

    • Author(s)
      Kawaguchi Y
    • Organizer
      Neuro2013
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 脳波リズムと視床-皮質サブネットワーク活動の解析2013

    • Author(s)
      牛丸弥香, 植田禎史, 川口泰雄
    • Organizer
      日本睡眠学会第38回定期学術集会
    • Place of Presentation
      秋田キャッスルホテル(秋田)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Neural circuit mechanism of reinforcement learning: new hypothesis on the mechanism of dopaminergic representation of reward prediction error2013

    • Author(s)
      Morita K, Morishima M, Sakai K, Kawaguchi Y
    • Organizer
      Neuro2013
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Selective participation of corticopontine and commissural neurons in ipsilateral corticocortical projections from the rat frontal cortex2013

    • Author(s)
      Ueta Y, Kawaguchi Y
    • Organizer
      Annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Multiple layer 5 corticopontine and commissural neurons relay cortical feedback from secondary to primary motor cortex2013

    • Author(s)
      Ueta Y, Otsuka T, Kawaguchi Y
    • Organizer
      NIPS International Workshop The sixth international Neural Microcircuit Conference "Functional Mechanism of Cortical Microcircuit"
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Classification of excitatory cortical neurons by their initial axonal outgrowth2013

    • Author(s)
      Hatanaka Y, Yamauchi K, Namikawa T, Kawaguchi Y
    • Organizer
      NIPS International Workshop The sixth international Neural Microcircuit Conference "Functional Mechanism of Cortical Microcircuit"
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Frontal cortical neuron activity during slow oscillation2013

    • Author(s)
      Ushimaru M, Kawaguchi Y
    • Organizer
      NIPS International Workshop The sixth international Neural Microcircuit Conference "Functional Mechanism of Cortical Microcircuit"
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Local circuitry of layer 6 spiny neurons in rat frontal cortex2013

    • Author(s)
      Karube F, Fujiyama F, Kawaguchi Y
    • Organizer
      NIPS International Workshop The sixth international Neural Microcircuit Conference "Functional Mechanism of Cortical Microcircuit"
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Involvements of Basal Ganglia Pathways in Reversal Learning and Time Preference: Predictions of the Corticostriatal Temporal Difference (TD) Hypothesis2013

    • Author(s)
      Morita K, Kawaguchi Y
    • Organizer
      2013 Annual Conference of the Society for Neuroeconomic EPFL
    • Place of Presentation
      Lausanne (Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Direction- and distance-dependent interareal connectivity of pyramidal cell subpopulations2013

    • Author(s)
      Ueta Y, Hirai Y, Otsuka T, Kawaguchi Y
    • Organizer
      The 3rd NIPS-CIN Joint Symposium
    • Place of Presentation
      生理学研究所(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Classification of excitatory cortical neurons by their initial axonal outgrowth2013

    • Author(s)
      Hatanaka Y, Yamauchi K, Namikawa T, Kawaguchi Y
    • Organizer
      The 3rd NIPS-CIN Joint Symposium
    • Place of Presentation
      生理学研究所(岡崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Locally limited conductance of IPSCs elicited by cortical fast spiking basket cell2013

    • Author(s)
      Kubota Y, Kondo S, Nomura M, Kawaguchi Y
    • Organizer
      Cell Symposia "The Networked Brain"
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of manipulations of the basal ganglia pathways on reversal learning and time preference: predictions of the corticostriatal temporal difference (TD) hypothesis with implications for addiction2013

    • Author(s)
      Morita K, Kawaguchi Y
    • Organizer
      2013 annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Differences in size of cortical synapses underlie distinct modes of inhibitory control2013

    • Author(s)
      Kubota Y, Kondo S, Nomura M, Karube F, Lübke J, Kawaguchi Y
    • Organizer
      2013 annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Excitatory neurons are classified into two distinct groups according to their initial axonal direction2013

    • Author(s)
      Hatanaka Y, Yamauchi K, Namikawa T, Kawaguchi Y
    • Organizer
      2013 annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Selective participation of corticopontine and commissural neurons in ipsilateral corticocortical projections from the rat frontal cortex2013

    • Author(s)
      Ueta Y, Kawaguchi Y
    • Organizer
      2013 annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Differential information processing through the basal ganglia-thalamo-cortical and cerebello-thalamo-cortical pathways2013

    • Author(s)
      Chiken S, Kawaguchi Y, Kimura M, Nambu A
    • Organizer
      日本比較生理生化学会 第35回大会
    • Place of Presentation
      イーグレひめじ(姫路)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 小脳入力と大脳基底核入力の視床-大脳皮質投射への作用2013

    • Author(s)
      知見 聡美、川口 泰雄、木村 實、南部 篤
    • Organizer
      第28 回日本大脳基底核研究会
    • Place of Presentation
      ラフォーレ修善寺(伊豆)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 大脳皮質のニューロンタイピングと結合マッピング

    • Author(s)
      川口泰雄
    • Organizer
      自然科学研究機構新分野創成センターシンポジウム
    • Place of Presentation
      星陵会館ホール東京)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Twenty cortical neuron types over 20 years

    • Author(s)
      Kawaguchi Y
    • Organizer
      The 3rd NIPS-CIN Joint Neuroscience Symposium
    • Place of Presentation
      生理学研究所(岡崎)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Pyramidal and GABAergic cell subnetworks in the cortex

    • Author(s)
      Kawaguchi Y
    • Organizer
      NEOCORTICAL ORGANIZATION 2
    • Place of Presentation
      生理学研究所(岡崎)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] Cortical Development2013

    • Author(s)
      Kageyama R, Guillemot F, Osumi N, Shimazaki T, Miyoshi G, Nieto M, Shi S-H, Kawaguchi Y, Masu M, Noda M, Mishina M, Huang W-C, Yamamori T
    • Total Pages
      282
    • Publisher
      Springer
    • Related Report
      2013 Annual Research Report
  • [Remarks] 生理学研究所大脳神経回路論研究部門

    • URL

      http://www.nips.ac.jp/circuit/

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report 2015 Annual Research Report 2014 Annual Research Report
  • [Remarks] 生理学研究所大脳神経回路論研究部門

    • URL

      http://www.nips.ac.jp/circuit/

    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-15   Modified: 2020-03-30  

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