| Budget Amount *help |
¥45,110,000 (Direct Cost: ¥34,700,000、Indirect Cost: ¥10,410,000)
Fiscal Year 2017: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2016: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2015: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
The integrative function of frontal cortex may rely on the synchronous firing of diverse neurons during oscillations. Fast-spiking (FS) cells, a subtype of inhibitory neurons, and thalamocortical inputs are supposed to play important roles in oscillation induction. For further understanding of cooperative activities among frontal cortical neurons, we analyzed thalamic inputs, synaptic connections with FS cells, and firing phases during oscillations in individual cortical cell subtypes. Consequently, we found cell subtype differences in thalamocortical inputs and firing phases during slow and gamma waves. Combined with local connection analysis, these findings suggest that individual FS cells do not selectively inhibit specific output subnetworks, but could synchronize diverse subcortical and corticocortical output channels in an integrative way.
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