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Development of the integrated technologies to analyze genomic bases of individuality

Research Project

Project/Area Number 25250024
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Genome biology
Research InstitutionNational Institute of Genetics

Principal Investigator

Fujiyama Asao  国立遺伝学研究所, 生命情報研究センター, 教授 (60142311)

Co-Investigator(Kenkyū-buntansha) Itoh Takehiko  東京工業大学, 生命理工学研究科, 教授 (90501106)
Co-Investigator(Renkei-kenkyūsha) Toyoda Atsushi  国立遺伝学研究所, 生命情報研究センター, 特任准教授 (10267495)
Noguchi Hideki  国立遺伝学研究所, 先端ゲノミクス推進センター, 特任准教授 (50333349)
Research Collaborator Fukuta Kentaro  
Tatsumoto Shoji  
Go Yasuhiro  
Ishida Takafumi  
Kuroki Yoko  
Project Period (FY) 2013-10-21 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥44,070,000 (Direct Cost: ¥33,900,000、Indirect Cost: ¥10,170,000)
Fiscal Year 2015: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2014: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2013: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Keywordsゲノム解析技術 / ゲノム変異 / ゲノム構造 / バイオインフォマティクス / ゲノム科学 / 個体ゲノム / 新規変異 / 全ゲノム解析
Outline of Final Research Achievements

This research project aims to establish technological bases to understand genomic characteristics of individual cell and body. The research group is one of the internationally recognized top-rate genome centers. The major finding of this research project is that the actual mutation rate is measured through large-scale genome analysis of chimpanzee parent-child trio and highly sophisticated bioinformatics. In addition, genomic characteristics of Japanese macaque (snow monkey) has also been decoded including establishment of the new reference genome sequence of the species.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (8 results)

All 2014 Other

All Int'l Joint Research (1 results) Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (2 results) (of which Invited: 1 results) Book (2 results) Remarks (2 results)

  • [Int'l Joint Research] メルボルン大学(オーストラリア)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Efficient de novo assembly of highly heterozygous genomes from whole-genome shotgun short reads.2014

    • Author(s)
      R. Kajitani, K. Toshimoto, H. Noguchi, A. Toyoda, Y. Ogura, M. Okuno, M. Yabana, M. Harada, E. Nagayasu, H. Maruyama, Y. Kohara, A. Fujiyama, T. Hayashi and T.Itoh
    • Journal Title

      Genome Research,

      Volume: 24 Issue: 8 Pages: 1384-1384

    • DOI

      10.1101/gr.170720.113

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 第3 世代1 分子シークエンサーによる新規大型ゲノム解読2014

    • Author(s)
      藤山 秋佐夫、野口 英樹、豊田 敦
    • Organizer
      日本人類遺伝学会
    • Place of Presentation
      東京都江戸川区(タワーホール船堀)
    • Year and Date
      2014-11-21
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 大規模全ゲノムシーケンシングによるニホンザルの種特異的ゲノム情報の探索2014

    • Author(s)
      福多賢太郎,野口英樹,豊田敦,長田直樹,郷康弘,石田貴文,伊佐正,藤山秋佐夫
    • Organizer
      日本霊長類学会
    • Place of Presentation
      大阪市西区(大阪科学技術センター)
    • Year and Date
      2014-07-04 – 2014-07-06
    • Related Report
      2014 Annual Research Report
  • [Book] 生命のビッグデータ利用の最前線2014

    • Author(s)
      藤山秋佐夫(分担執筆)
    • Publisher
      シーエムシー出版
    • Related Report
      2014 Annual Research Report
  • [Book] 生命のビッグデータ利用の最前線、第2章 大規模データ生産を基盤とするゲノミクスの最先端2014

    • Author(s)
      藤山秋佐夫、植田充美、藤田信之、割石博之、奥野恭史、黒川顕、高田豊行、城石俊彦、藤淵航、内山郁夫、阿部貴史、池村淑道、白井剛、辻敏之、大浪修一、間野修平、金谷重彦、馬場健史、中村由紀子
    • Total Pages
      231
    • Publisher
      シーエムシー出版
    • Related Report
      2013 Annual Research Report
  • [Remarks] 先端ゲノミクス推進センターホームページ

    • URL

      https://www.nig.ac.jp/nig/ja/research/organization-top/laboratories/advanced-genomics-center

    • Related Report
      2015 Annual Research Report
  • [Remarks] 伊藤研究室ホームページ

    • URL

      http://www.bio.titech.ac.jp/laboratory/itoh-kotera/index.html

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2013-10-24   Modified: 2019-07-29  

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