Development of the integrated technologies to analyze genomic bases of individuality
Project/Area Number |
25250024
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Research Category |
Grant-in-Aid for Scientific Research (A)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Genome biology
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Research Institution | National Institute of Genetics |
Principal Investigator |
Fujiyama Asao 国立遺伝学研究所, 生命情報研究センター, 教授 (60142311)
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Co-Investigator(Kenkyū-buntansha) |
Itoh Takehiko 東京工業大学, 生命理工学研究科, 教授 (90501106)
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Co-Investigator(Renkei-kenkyūsha) |
Toyoda Atsushi 国立遺伝学研究所, 生命情報研究センター, 特任准教授 (10267495)
Noguchi Hideki 国立遺伝学研究所, 先端ゲノミクス推進センター, 特任准教授 (50333349)
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Research Collaborator |
Fukuta Kentaro
Tatsumoto Shoji
Go Yasuhiro
Ishida Takafumi
Kuroki Yoko
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Project Period (FY) |
2013-10-21 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥44,070,000 (Direct Cost: ¥33,900,000、Indirect Cost: ¥10,170,000)
Fiscal Year 2015: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2014: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2013: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
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Keywords | ゲノム解析技術 / ゲノム変異 / ゲノム構造 / バイオインフォマティクス / ゲノム科学 / 個体ゲノム / 新規変異 / 全ゲノム解析 |
Outline of Final Research Achievements |
This research project aims to establish technological bases to understand genomic characteristics of individual cell and body. The research group is one of the internationally recognized top-rate genome centers. The major finding of this research project is that the actual mutation rate is measured through large-scale genome analysis of chimpanzee parent-child trio and highly sophisticated bioinformatics. In addition, genomic characteristics of Japanese macaque (snow monkey) has also been decoded including establishment of the new reference genome sequence of the species.
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Report
(4 results)
Research Products
(8 results)
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[Journal Article] Efficient de novo assembly of highly heterozygous genomes from whole-genome shotgun short reads.2014
Author(s)
R. Kajitani, K. Toshimoto, H. Noguchi, A. Toyoda, Y. Ogura, M. Okuno, M. Yabana, M. Harada, E. Nagayasu, H. Maruyama, Y. Kohara, A. Fujiyama, T. Hayashi and T.Itoh
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Journal Title
Genome Research,
Volume: 24
Issue: 8
Pages: 1384-1384
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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