| Budget Amount *help |
¥46,930,000 (Direct Cost: ¥36,100,000、Indirect Cost: ¥10,830,000)
Fiscal Year 2016: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2015: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2014: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2013: ¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
|
|---|
| Outline of Final Research Achievements |
For DNA replication ignition complex made of DnaA and others, we constructed a coarse-grained model first, which is reverse-mapped to obtain atomic structure of the complex for the first time. The constructed model is made of three sub-complexes. By biochemical experiments, it was shown to be consistent with the experimental data. This study revealed near-atomic structural model of the DNA replication initiation complex.
|
