| Budget Amount *help |
¥37,180,000 (Direct Cost: ¥28,600,000、Indirect Cost: ¥8,580,000)
Fiscal Year 2016: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2015: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2014: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
Fiscal Year 2013: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
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| Outline of Final Research Achievements |
We aimed to understand the mechanism for coordinated proliferation of the eukaryotic host cell and the chloroplast which played a pivotal role in endosymbiotic establishment of the chloroplast. By characterizing eukaryotic algae, we found (1) that the division of chloroplast of both primary and secondary endosymbiotic origin is restricted to S phase by S-phase-specific expression of nucleus-encoded chloroplast division genes/proteins, (2) that initiation of chloroplast division site constriction is required for the host cell cycle progression, and (3) that the host cell cycle progression is restricted to night when photosynthesis does not operate to avoid photosynthetic oxidative stress. These results suggest that the division synchronization of the host cell and the chloroplast is enabled by interactive restrictions between the host cell and the chloroplast.
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