| Co-Investigator(Kenkyū-buntansha) |
若生 俊行 国立研究開発法人農業生物資源研究所, その他部局等, 主任研究員 (80373257)
近江戸 伸子 神戸大学, 人間発達環境学研究科, 教授 (30343263)
高田 英昭 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 (20455207)
内山 進 大阪大学, 工学研究科, 教授 (90335381)
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| Budget Amount *help |
¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2017: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2015: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2014: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2013: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
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| Outline of Final Research Achievements |
Chromosome structure has been an enigma through these three centuries. We tried to elucidate the inner structure of the chromosome by visualization of nucleosome positions by slice and view method using focused ion beam/scanning electron microscopy. As a result, random distribution of nucleosomes were revealed through the chromosome and no regular structure was not detected. On the other hand, we analyzed the chromosome scaffold and revealed that the scaffold consisted with helical double stranded structure. This structure accounts the rigid and flexible nature of the chromosome.
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