The World Mental Health Japan Follow-up: a 10-year cohort study of mental disorders in a community population

• Project/Area Number: 25253045
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: The University of Tokyo
• Principal Investigator: Kawakami Norito 東京大学, 大学院医学系研究科(医学部), 教授 (90177650)
• Co-Investigator(Kenkyū-buntansha): 島津 明人 東京大学, 医学(系)研究科(研究院), 准教授 (80318724) ; 宮本 有紀 東京大学, 医学(系)研究科(研究院), 講師 (10292616) ; 梅田 麻希 東京大学, 医学(系)研究科(研究院), 助教 (40424311) ; 馬場 俊明 東京大学, 大学院医学系研究科(医学部), 助教 (20781016)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥36,790,000 (Direct Cost: ¥28,300,000、Indirect Cost: ¥8,490,000); Fiscal Year 2016: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000); Fiscal Year 2015: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000); Fiscal Year 2014: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000); Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
• Keywords: 精神保健疫学 / 精神疾患 / 前向きコホート / 罹患率 / 危険因子 / 疫学 / 精神保健 / コホート研究 / 社会疫学 / 脳神経疾患 / ストレス / 遺伝子 / 医療・福祉 / 精神障害 / 社会医学

Outline of Final Research Achievements

There was only a few prospective cohort studies of mental disorders in a community population in the world. The present study conduct a prospective mental health epidemiology re-interviewing 1,859 respondents to the World Mental Health Survey Japan that was conducted about 10 years ago. Trained interviewers visited a total of 1,465 respondents in Nagasaki, Okayama, and Tamano cities, and interviewed 581, and obtained saliva samples for genomic analysis from 475.

Research Products

• [Int'l Joint Research] ハーバード大学医学部(米国)
• [Int'l Joint Research] ハーバード大学医学部(米国)
• [Journal Article] Posttraumatic stress disorder in the World Mental Health Surveys. (2017)
  • Author(s): Koenen KC, et al.
  • Journal Title: Psychol Med Volume: 7 Issue: 13 Pages: 1-15
  • DOI: 10.1017/s0033291717000708
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Effect of socioeconomic conditions on health care utilization in marital violence: a cross-sectional investigation from the Japanese Study on Stratification, Health, Income, and Neighborhood. (2017)
  • Author(s): Umeda M, Kawakami N, Miller E.
  • Journal Title: Int J Equity Health. Volume: 16 Issue: 1 Pages: 41-41
  • DOI: 10.1186/s12939-017-0528-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association of DSM-IV Posttraumatic Stress Disorder With Traumatic Experience Type and History in the World Health Organization World Mental Health Surveys. (2017)
  • Author(s): Liu H, et al.
  • Journal Title: JAMA Psychiatry. Volume: 74 Issue: 3 Pages: 270-281
  • DOI: 10.1001/jamapsychiatry.2016.3783
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Posttraumatic stress disorder associated with unexpected death of a loved one: Cross-national findings from the world mental health surveys. (2017)
  • Author(s): Atwoli L, et al.
  • Journal Title: Depress Anxiety. Volume: 34 Issue: 4 Pages: 315-326
  • DOI: 10.1002/da.22579
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Undertreatment of people with major depressive disorder in 21 countries. (2017)
  • Author(s): Thornicroft G, et al.
  • Journal Title: Br J Psychiatry. Volume: 210 Issue: 2 Pages: 119-124
  • DOI: 10.1192/bjp.bp.116.188078
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Childhood adversities and adult-onset chronic pain: Results from the World Mental Health Survey, Japan. (2015)
  • Author(s): Stickley A, Koyanagi A, Kawakami N; WHO World Mental Health Japan Survey Group.
  • Journal Title: Eur J Pain Volume: in press Issue: 10 Pages: 1418-1427
  • DOI: 10.1002/ejp.672
  • Peer Reviewed
• [Journal Article] Barriers to mental health care in Japan: Results from the World Mental Health Japan Survey. (2015)
  • Author(s): Kanehara A, Umeda M, Kawakami N; the World Mental Health Japan Survey Group.
  • Journal Title: Psychiatry Clin Neurosci. Volume: in press Issue: 9 Pages: 523-533
  • DOI: 10.1111/pcn.12267
  • Peer Reviewed
• [Journal Article] How well can post-traumatic stress disorder be predicted from pre-trauma risk factors? An exploratory study in the WHO World Mental Health Surveys. (2014)
  • Author(s): Kessler RC, Rose S, Koenen KC, et al
  • Journal Title: World Psychiatry. Volume: 13 Issue: 3 Pages: 265-74
  • DOI: 10.1002/wps.20150
  • Peer Reviewed
• [Journal Article] DSM-5 and ICD-11 definitions of posttraumatic stress disorder: investigating "narrow" and "broad" approaches. (2014)
  • Author(s): Stein DJ, McLaughlin KA, Koenen KC, Atwoli L, Friedman MJ, Hill ED, Maercker A, Petukhova M, Shahly V, van Ommeren M, Alonso J, Borges G, de Girolamo G, de Jonge P, Demyttenaere K, Florescu S, Karam EG, Kawakami N, Matschinger H, Okoliyski M, Posada-Villa J, Scott KM, Viana MC, Kessler RC.
  • Journal Title: Depress Anxiety. Volume: 31 Issue: 6 Pages: 494-505
  • DOI: 10.1002/da.22279
  • Peer Reviewed
• [Journal Article] One-year test-retest reliability of a Japanese web-based version of the WHO Composite International Diagnostic Interview (CIDI) for major depression in a working population. (2014)
  • Author(s): Shimoda H, Inoue A, Tsuno K, Kawakami N.
  • Journal Title: Int J Methods Psychiatr Res. Volume: in press Issue: 3 Pages: 204-212
  • DOI: 10.1002/mpr.1437
  • Peer Reviewed
• [Journal Article] Trauma and posttraumatic stress disorder in Japan: Results from the World Mental Health Japan Survey. (2014)
  • Author(s): Kawakami N, Tsuchiya M, Umeda M, Koenen KC, Kessler RC; World Mental Health
  • Journal Title: J Psychiatr Res. Volume: 53 Pages: 157-65
  • DOI: 10.1016/j.jpsychires.2014.01.015
  • Peer Reviewed
• [Journal Article] Associations between mental disorders and subsequent onset of hypertension. (2014)
  • Author(s): Stein DJ, et al.
  • Journal Title: Gen Hosp Psychiatry. Volume: 36 Issue: 2 Pages: 142-9
  • DOI: 10.1016/j.genhosppsych.2013.11.002
  • Peer Reviewed
• [Journal Article] Cumulative traumas and risk thresholds: 12-month PTSD in the World Mental Health (WMH) surveys. (2014)
  • Author(s): Karam EG, et al.
  • Journal Title: Depress Anxiety. Volume: 31 Issue: 2 Pages: 130-42
  • DOI: 10.1002/da.22169
  • Peer Reviewed
• [Journal Article] Fruit and vegetable consumption in adolescence and health in early adulthood: a longitudinal analysis of the statistics Canada's National Population Health Survey. (2013)
  • Author(s): Takaoka Y, Kawakami N.
  • Journal Title: .BMC Public Health. Volume: 13 Issue: 1 Pages: 1206-1206
  • DOI: 10.1186/1471-2458-13-1206
  • Peer Reviewed
• [Presentation] Contribution of epidemiology to community mental health (2014)
  • Author(s): Norito Kawakami
  • Organizer: 2014 BeSeTo Tokyo Conference on Neuropsychiat
  • Place of Presentation: 東京
  • Year and Date: 2014-07-26
  • Invited
• [Presentation] Research approaches to cultural differences in epidemiology (MIDUS/MIDJA) (2014)
  • Author(s): Norito Kawakami
  • Organizer: DFG-JSPS Symposium: Shared Pathways in CNS Disorders
  • Place of Presentation: ミュンヘン
  • Year and Date: 2014-06-30 – 2014-07-02
  • Invited
• [Presentation] 世界の精神保健調査から見えてくるもの ー気分、不安、物質使用性障害 (2013)
  • Author(s): 川上憲人
  • Organizer: 第109回日本精神神経学会学術総会
  • Place of Presentation: 福岡市
  • Invited