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Investigation of adverse health effects of environmental chemicals by a birth cohort study:focused on gene environment interactions

Research Project

Project/Area Number 25253050
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene and public health
Research InstitutionHokkaido University

Principal Investigator

Kishi Reiko  北海道大学, 環境健康科学研究教育センター, 特別招へい教授 (80112449)

Co-Investigator(Kenkyū-buntansha) IKENO Tamiko  北海道大学, 環境健康科学研究教育センター, 客員研究員 (80569715)
ARAKI Atsuko  北海道大学, 環境健康科学研究教育センター, 准教授 (00619885)
MIYASHITA Chihiro  北海道大学, 環境健康科学研究教育センター, 特任准教授 (70632389)
NAKAJIMA Sonomi  札幌医科大学, 保健医療学部, 准教授 (70325877)
SASAKI Seiko  北海道大学, 医学(系)研究科(研究院), 助教 (30448831)
HANAOKA Tomoyuki  北海道大学, 環境健康科学研究教育センター, 客員教授 (00228503)
安住 薫  北海道大学, 環境健康科学研究教育センター, 客員研究員 (90221720)
Co-Investigator(Renkei-kenkyūsha) KAJIWARA Junboku  福岡県保健環境研究所, 保健科学部生活化学課, 専門研究員 (80446848)
MATSUURA Hideyuki  北海道大学, 大学院・農学研究院・応用生命科学部門生命有機化学分野, 准教授 (20344492)
MUROHASHI Harumitsu  北海道大学, 教育学研究科(研究院), 教授 (00182147)
SIRAISHI Hideaki  北海道大学, 大学院・医学研究科・生殖, 発達医学講座, 助教 (80374411)
SATA Fumihiro  東京医科歯科大, 難治疾患研究所, 非常勤講師 (90187154)
SAIJO Yasuaki  旭川医科大学, 医学部, 教授 (70360906)
YOSHIOKA Eiji  旭川医科大学, 医学部, 准教授 (70435957)
AZUMI Kaoru  北海道大学, 探索医療教育研究センター, 特任講師 (90221720)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥47,450,000 (Direct Cost: ¥36,500,000、Indirect Cost: ¥10,950,000)
Fiscal Year 2015: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2014: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2013: ¥29,510,000 (Direct Cost: ¥22,700,000、Indirect Cost: ¥6,810,000)
Keywords母子保健 / 環境化学物質 / 次世代影響 / リスク評価 / 神経行動発達 / 環境遺伝交互作用 / 出生時体格 / 出生コホート / 母子手帳 / 神経発達 / 母子健康
Outline of Final Research Achievements

20,000 mother-infant pairs were recruited in 40 obstetric hospitals in Hokkaido, Japan. We investigated the association between prenatal exposure to tobacco smoke, dioxins and perfluorinated compounds and several developmental outcomes such as e infant growth, neurodevelopment, and allergy after birth until 8 year-old.
We observed that prenatal chemical exposures were associated with (1) peroxisomal proliferator-activated receptor beta (PPARβ) genetic polymorphism on serum lipid in maternal blood, (2) DNA repairing (X-ray cross-complementing gene 1; XRCC1) genetic polymorphisms on infant birth weight, (3) insulin growth factor 2 (IGF2) methylation in cord blood, and (4) infant neurodevelopment at 1.5-year-old. In addition, we attempted to identify the risk factor of the attention deficit/hyperactivity disorder (AD/HD), the result showed that alcohol drinking and smoking increased the odds ratio.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (107 results)

All 2016 2015 2014 2013 Other

All Journal Article (43 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 26 results,  Open Access: 16 results,  Acknowledgement Compliant: 2 results) Presentation (56 results) (of which Int'l Joint Research: 3 results) Book (2 results) Remarks (6 results)

  • [Journal Article] Prenatal exposure to perfluorinated chemicals and neurodevelopment in early infancy: The Hokkaido Study2016

    • Author(s)
      H. Goudarzi, S. Nakajima, T. Ikeno, S. Sasaki, S. Kobayashi, C. Miyashita, S. Ito, A. Araki, H. Nakazawa and R. Kishi
    • Journal Title

      Sci Total Environ

      Volume: 541 Pages: 1002-1010

    • DOI

      10.1016/j.scitotenv.2015.10.017

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Associations of Perfluoroalkyl Substances (PFASs) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK).2015

    • Author(s)
      M. A. Verner, A. E. Loccisano, N. H. Morken, M. Yoon, H. Wu, R. McDougall, M. Maisonet, M. Marcus, R. Kishi, C. Miyashita, M. H. Chen, W. S. Hsieh, M. E. Andersen, H. J. Clewell, 3rd and M. P. Longnecker.
    • Journal Title

      Environ Health Perspect

      Volume: 123 Issue: 12 Pages: 1317-1317

    • DOI

      10.1289/ehp.1408837

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Demographic, behavioral, dietary and socioeconomic characteristics related to persistent organic pollutants and mercury levels in pregnant woman in Japan2015

    • Author(s)
      Miyashita C., Sasaki S., Saijo Y., Okada E., Kobayashi S., Baba T., Kajiwara J., Todaka T., Iwasaki Y., Nakazawa H., Hachiya N., Yasutake A., Murata K., Kishi R.
    • Journal Title

      Chemosphere

      Volume: 133 Pages: 13-21

    • DOI

      10.1016/j.chemosphere.2015.02.062

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of in utero exposure to polychlorinated biphenyls, methylmercury, and polyunsaturated fatty acids on birth size2015

    • Author(s)
      C. Miyashita, S. Sasaki, T. Ikeno, A. Araki, S. Ito, J. Kajiwara, T. Todaka, N. Hachiya, A. Yasutake, K. Murata, T. Nakajima and R. Kishi
    • Journal Title

      Sci Total Environ

      Volume: 533 Pages: 256-265

    • DOI

      10.1016/j.scitotenv.2015.06.108

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Association of Prenatal Exposure to Perfluorinated Chemicals with Maternal Fatty Acids during Pregnancy and the Birth Weight of their Offspring:The Hokkaido Study2015

    • Author(s)
      Reiko Kishi, Tamie Nakajima, Houman Goudarzi, Sachiko Kobayashi, Seiko Sasaki, Emiko Okada, Chihiro Miyashita, Sachiko Itoh, Atsuko Araki, Tamiko Ikeno, Yusuke Iwasaki, and Hiroyuki Nakazawa
    • Journal Title

      Environmental Health Perspective

      Volume: 印刷中 Issue: 10 Pages: 1038-1045

    • DOI

      10.1289/ehp.1408834

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prenatal maternal blood triglyceride and fatty acid levels in relation to exposure to di(2-ethylhexyl)phthalate: a cross-sectional study.2015

    • Author(s)
      Jia X, Harada Y, Tagawa M, Naito H, Hayashi Y, Yetti H, Kato M, Sasaki S, Araki A, Miyashita C, Ikeno T, Kishi R, Nakajima T.
    • Journal Title

      Environ Health Prev Med.

      Volume: In press Issue: 3 Pages: 168-178

    • DOI

      10.1007/s12199-014-0440-4

    • NAID

      210000000370

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 胎児期の母の受動喫煙と児の出生体重に関する最近の研究動向2015

    • Author(s)
      小林澄貴, 荒木敦子, 佐々木成子, 池野多美子, 宮下ちひろ, 伊藤佐智子 , 岸玲子
    • Journal Title

      北海道公衆衛生学雑誌

      Volume: 28 Pages: 37-48

    • NAID

      120005600756

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【講座 子どもを取り巻く環境と健康】第10回 乳幼児のアレルギーと胎児期・小児期の可塑剤・難燃剤曝露2015

    • Author(s)
      荒木敦子, アイツバマイゆふ, 岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 876-881

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第8回 胎児期の環境化学物質曝露が出生体重と生後発育へ与える影響2015

    • Author(s)
      湊屋街子, 岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 719-724

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第6回 妊娠期化学物質曝露と母の栄養状態および次世代影響2015

    • Author(s)
      那須民江
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 559-564

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第7回 喫煙、受動喫煙による児への影響2015

    • Author(s)
      佐々木成子, 小林澄貴, 岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 637-643

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 胎児期の有機フッ素化合物曝露による児の健康への影響2015

    • Author(s)
      荒木敦子, 宮下ちひろ, 岸玲子
    • Journal Title

      Endcrine Disrupter News Letter

      Volume: 18 Pages: 5-5

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第5回 短半減期化学物質の曝露実態2015

    • Author(s)
      荒木敦子, アイツバマイゆふ, 岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 485-490

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第9回 乳幼児のアレルギー・感染症へのダイオキシン類、有機フッ素系化学物質曝露による影響2015

    • Author(s)
      宮下ちひろ, 岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 805-810

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 胎児期のPCBsダイオキシン類による出生体重とアレルギー感染症に与える影響2015

    • Author(s)
      宮下ちひろ, 岸玲子
    • Journal Title

      Endcrine Disrupter News Letter

      Volume: 18 Pages: 3-3

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第1回「奪われし未来」にしない2015

    • Author(s)
      岸玲子
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 193-199

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 世界における出生コーホート研究の現状2015

    • Author(s)
      岸玲子
    • Journal Title

      Endcrine Disrupter News Letter

      Volume: 18 Pages: 1-1

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 【講座 子供を取り巻く環境と健康】第3回 POPs(ダイオキシン・PCB類)の曝露実態2015

    • Author(s)
      梶原淳睦
    • Journal Title

      公衆衛生

      Volume: 79 Pages: 347-352

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Effects of prenatal Leydig cell function on the ratio of the second to fourth digit lengths in school-aged children2015

    • Author(s)
      Mitsui T., Araki A., Imai A, Sato S., Miyashita C., Ito S., Sasaki S., Kitta T., Moriya K. Cho K., Morioka K., Kihsi R., Nonomura K
    • Journal Title

      PLOS One

      Volume: 10(3) Issue: 3 Pages: e0120636-e0120636

    • DOI

      10.1371/journal.pone.0120636

    • NAID

      120005606031

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 胎児期の母の受動喫煙と児の出生体重に関する最近の研究動向2015

    • Author(s)
      小林澄貴, 荒木敦子, 佐々木成子, 池野多美子, 宮下ちひろ, 伊藤佐智子, 岸玲子
    • Journal Title

      北海道公衆衛生学雑誌

      Volume: 28(2) Pages: 37-48

    • NAID

      120005600756

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of maternal whole blood fatty acid status during the prenatal period with term birth dimensions: a cross- sectional study2014

    • Author(s)
      Jia X., Tagawa T., Yatsuya H., Naito H., Hayashi., Husna Y., Sasaki S., Araki A., Miyashita C., Ikeno T., Kishi R., Nakajima T
    • Journal Title

      J Perinat Med

      Volume: in press Issue: 5

    • DOI

      10.1515/jpm-2014-0277

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prenatal maternal blood triglyceride and fatty acid levels in relation to exposure to di(2-ethylhexyl) phthalate: a cross-sectional study.2014

    • Author(s)
      Jia X., Harada Y., Tagawa M., Naito H., Hayashi Y., Yetti H., Kato M., Sasaki S., Araki A., Miyashita C., Ikeno T., Kishi R., Nakajima T
    • Journal Title

      Environ Health Prev Med

      Volume: in press

    • NAID

      210000000370

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between maternal exposure to di(2-ethylhexyl) phthalate and reproductive hormone levels in fetal blood: The Hokkaido Study on Environment and Children's Health2014

    • Author(s)
      Araki A., Mitsui T., Miyashita C., Nakajima T., Naito H., Ito S., Sasaki S., Cho K., Ikeno T., Nonomura K., Kishi R.
    • Journal Title

      PLOS One

      Volume: 9(10) Issue: 10 Pages: e109039-e109039

    • DOI

      10.1371/journal.pone.0109039

    • NAID

      120005476155

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prenatal exposure to perfluoroalkyl acids and allergic diseases in earlychildhood.2014

    • Author(s)
      Okada E, Sasaki S, Kashino I, Matsuura H, Miyashita C, Kobayashi S, Itoh K, Ikeno T, Tamakoshi A, Kishi R.
    • Journal Title

      Environment International

      Volume: 65 Pages: 127-134

    • DOI

      10.1016/j.envint.2014.01.007

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【公害・環境問題の変貌と新展開】環境化学物質の次世代影響 出生コホート研究による成果と今後の課題2014

    • Author(s)
      岸 玲子
    • Journal Title

      公衆衛生

      Volume: 78(8) Pages: 547-552

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 【公害・環境問題の変貌と新展開】環境科学物質の次世代影響 出生コホート研究による成果と今後の課題2014

    • Author(s)
      岸玲子
    • Journal Title

      公衆衛生

      Volume: 78 Pages: 547-552

    • Related Report
      2014 Annual Research Report
  • [Journal Article] DOHaDの視点に立った生涯にわたるヘルスケア2014

    • Author(s)
      佐田文宏
    • Journal Title

      小児保健研究

      Volume: 73(6) Pages: 769-775

    • NAID

      40020277517

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 発達障害におけるワーキングメモリー特性を生かした学習支援2014

    • Author(s)
      室橋春光
    • Journal Title

      LD研究 研究と実践

      Volume: 23(2) Pages: 134-141

    • Related Report
      2014 Annual Research Report
    • Open Access
  • [Journal Article] Dioxins and PCBs concentrations in umbilical cord blood collected in Hokkaidou, Japan2014

    • Author(s)
      Jumboku Kajiwara, Takashi Todaka, Hironori Hirakawa, Takashi Miyawaki, Tamiko Ikeno, Cihiro Miyasita, Sachiko Itoh, Seiko Sasaki, Reiko KIshi, Masutaka Furue
    • Journal Title

      Organohalogen Compounds

      Volume: Vol. 76 Pages: 1481-1484

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Concentration of Dechlorane Plus in fish samples collected in Kyushu district, western Japan.2014

    • Author(s)
      Hori Tsuguhide, Takashi Miyawaki, Koji Takahashi, Daisuke Yasutake, Takamitsu Yamamoto, Jumboku Kajiwara, Takahiro Watanabe
    • Journal Title

      Organohalogen Compounds

      Volume: Vol. 76 Pages: 900-903

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Determination of hexabromocyclododecane in fish samples collected from Japanese markets2014

    • Author(s)
      Koji Takahashi, Tsuguhide Hori, Jumboku Kajiwara, Takahiro Watanabe
    • Journal Title

      Organohalogen Compounds.

      Volume: Vol. 76 Pages: 930-933

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polychlorinated biphenyls concentrations in blood of Yusho patients during medical check-ups performed in 2012.2014

    • Author(s)
      Miyawaki T, Todaka T, Hirakawa H, Hori T, Kajiwara J, Hirata T, Uchi H, Furue M.
    • Journal Title

      Organohalogen Compounds

      Volume: Vol. 76 Pages: 1457-1459

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between maternal antenatal depression and infant development: a hospital-based prospective cohort study2014

    • Author(s)
      Otake Y, Nakajima S, Uno A, Kato S, Sasaki S, Yoshioka E, Ikeno T, Kishi R
    • Journal Title

      Environment Health Preventive Medicine

      Volume: 19(1) Issue: 1 Pages: 30-45

    • DOI

      10.1007/s12199-013-0353-7

    • NAID

      210000000292

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Temporal trends of perfiuoroalkyl acids in plasma samples of pregnant women in Hokkaido, Japan, 2003-2011.2014

    • Author(s)
      Okada E, Kashino I, Matsuura H, Sasaki S, Miyashita C, Yamamoto J, Ikeno T, Ito Y, Matsumura T, Yamakoshi A, Kishi R.
    • Journal Title

      Environment International

      Volume: 60 Pages: 89-96

    • DOI

      10.1016/j.envint.2013.07.013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] First-trimester serum folate levels and subsequent risk of abortion and preterm birth among Japanese women with singleton pregnancies2013

    • Author(s)
      Yamada T, Morikawa M, Yamada T, Kishi R, Sengoku K, Endo T, Saito T, Cho K, Minakami H.
    • Journal Title

      Archives of gynecology and obstetrics

      Volume: 287 Issue: 1 Pages: 9-14

    • DOI

      10.1007/s00404-012-2501-5

    • NAID

      120005358926

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women2013

    • Author(s)
      Kobayashi S, Sata F, Sasaki S, Ban S, Miyashita C, Okada E, Limpar M, Yoshioka E, Kajiwara J, Todaka T, Saijo Y, Kishi R
    • Journal Title

      Toxicology Letters

      Volume: 219(3) Issue: 3 Pages: 269-278

    • DOI

      10.1016/j.toxlet.2013.03.013

    • NAID

      120005295676

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ten years of progress in the Hokkaido birth cohort study on environment and children's health : cohort profile--updated 2013.2013

    • Author(s)
      Kishi R, Kobayashi S, Ikeno T, Araki A, Miyashita C, Itoh S, Sasaki S, Okada E, Kobayashi S, Kashino I, Itoh K, Nakajima S ; Members of the Hokkaido Study on Environment and Children's Health.
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 18 Issue: 6 Pages: 429-450

    • DOI

      10.1007/s12199-013-0357-3

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 妊婦のダイオキシン類代謝酵素遺伝子多型と母体血中ダイオキシン類濃度との関連2013

    • Author(s)
      小林澄貴, 佐田文宏, 佐々木成子, 坂晋, 宮下ちひろ, 岡田恵美子, Limpar Mariko, 吉岡英治, 梶原淳睦, 戸高尊, 西條泰明, 岸玲子小林澄貴, 佐田文宏, 佐々木成子, 坂晋, 宮下ちひろ, 岡田恵美子, Limpar Mariko, 吉岡英治, 梶原淳睦, 戸高尊, 西條泰明, 岸玲子
    • Journal Title

      北海道医学雑誌

      Volume: 88 Pages: 145-145

    • NAID

      10031196495

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 北海道における妊婦の血中有機フッ素化合物濃度の経年変化2013

    • Author(s)
      岡田恵美子, 樫野いく子, 松浦英幸, 佐々木成子, 宮下ちひろ, 山本潤, 池野多美子, 伊藤陽一, 松村徹, 玉腰暁子, 岸玲子
    • Journal Title

      北海道医学雑誌

      Volume: 88 Pages: 203-203

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Blood levels of PCDDs, PCDFs, and coplanar PCBs in Yusho mothers and their descendants: Association with fetal Yusho disease2013

    • Author(s)
      Kiyomi Tsukimori, Hirohi Uchi, Shouji Tokunaga , Fumiko Yasukawa, Takahiro Chiba, Jumboku Kajiwara, Teruakai Hirata, Masutake Furue, et al.
    • Journal Title

      Chemosphere

      Volume: Feb;90(5) Pages: 1581-1588

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 血液中ダイオキシン、PCB濃度測定のクロスチェック2013

    • Author(s)
      梶原淳睦, 戸高尊, 平川博仙, 堀就英, 安武大輔, 宮脇崇, 飛石和大, 高尾佳子, 平田輝昭, 内博史, 古江増隆
    • Journal Title

      福岡医学雑誌

      Volume: 104(4) Pages: 104-109

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS2013

    • Author(s)
      Tobiishi K, Suzuki S, Todaka T, Hirakawa H, Hori T, Kajiwara J, Hirata T, Iida T, Uchi H, Furue M
    • Journal Title

      Fukuoka Igaku Zasshi

      Volume: Apr. 104(4) Pages: 128-135

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] THE SURVEY OF THE EXPOSURE TO DIOXINS AND OTHER CHEMICAL COMPOUNDS IN HUMANS (2)- DIOXINS AND OTHER CHEMICAL COMPOUNDS CONCENTRATION IN HUMAN BODIES OF GENERAL PUBLIC IN JAPAN AND INTAKE SURVEY FROM FOOD2013

    • Author(s)
      Saito M, Nagasaka Y, Takano K, Yamamoto M, Arisawa K, Chisaki Y, Hijiya M, Matsumura T
    • Journal Title

      Organohalogen Compd

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Effects of prenatal exposure to perfluoroalkyl acids on risk of allergic diseases at 4 years old children: The Hokkaido Study2015

    • Author(s)
      H. Goudarzi, S. Kobayashi, C. Chen, A. Araki, C. Miyashita, S. Ito and R. Kishi
    • Organizer
      第67回北海道公衆衛生学会
    • Place of Presentation
      旭川医科大学 (北海道・旭川市)
    • Year and Date
      2015-11-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 胎児期の母と学童期の児の喫煙曝露とADHD-RSとの関連‐北海道スタディ‐2015

    • Author(s)
      西原進吉,池野多美子,小林澄貴,佐々木成子,岸玲子
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール (長崎県・長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] 妊娠初期における北海道内女性労働者の記述疫学的考察2015

    • Author(s)
      小林澄貴, 宮下ちひろ, 荒木敦子, 池野多美子, 伊藤佐智子, H. Goudarzi, 花岡知之 , 岸玲子
    • Organizer
      第95回北海道医学大会 (平成27年度日本産業衛生学会北海道地方会)
    • Place of Presentation
      旭川建設労働者福祉センター (北海道・旭川市)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effects of maternal AHR, CYP1A1 and GSTM1 polymorphisms and dioxins on infant birth weight: The Hokkaido Study2015

    • Author(s)
      S. Kobayashi, C. Miyashita, S. Sasaki, A. Araki, F. Sata, S. Ban, J. Kajiwara, T. Todaka and R. Kishi
    • Organizer
      27th Conference of the International Society for Environmental Epidemiology (ISEE2015)
    • Place of Presentation
      Reboucas Conference Center, Sao Paulo (Brazil)
    • Year and Date
      2015-08-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prenatal BPA exposure and cord blood adipokines, birth weight and child growth: the Hokkaido Study of Environment and Children’s health2015

    • Author(s)
      M. Minatoya, S. Sasaki, A. Araki, C. Miyashita, J. Yamamoto, T. Matsumura and R. Kishi
    • Organizer
      27th Conference of the International Society for Environmental Epidemiology (ISEE2015)
    • Place of Presentation
      Reboucas Conference Center, Sao Paulo (Brazil)
    • Year and Date
      2015-08-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Association of Prenatal Exposure to Perfluorinated Chemicals with Maternal Fatty Acids during Pregnancy and the Birth Weight of their Offspring: The Hokkaido Study2015

    • Author(s)
      H. Goudarzi
    • Organizer
      27th Conference of the International Society for Environmental Epidemiology (ISEE2015)
    • Place of Presentation
      Reboucas Conference Center, Sao Paulo (Brazil)
    • Year and Date
      2015-08-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 胎児期ビスフェノールA曝露影響に関する臍帯血DNA網羅的メチル化解析-北海道スタディ2015

    • Author(s)
      小林祥子, 三浦りゅう, 川口章夫, 宮下ちひろ, 三宅邦夫, 松村徹, 山本潤, 石塚真由美, 荒木敦子, 久保田健夫, 岸玲子
    • Organizer
      第4回日本DOHaD研究学術集会
    • Place of Presentation
      昭和大学 (東京都・品川区)
    • Year and Date
      2015-08-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 有機塩素系農薬への胎児期曝露による児の性ホルモン濃度への影響:北海道スタディ2015

    • Author(s)
      荒木敦子、宮下ちひろ、金沢文子、伊藤佐智子、三井貴彦、佐々木成子、水谷太,苣木洋一,野々村克也、岸玲子
    • Organizer
      第85回日本衛生学会学術総会.
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 臍帯血ビスフェノールA濃度と児のIGF2 DNAメチル化との関連-北海道スタディ2015

    • Author(s)
      小林祥子,安住薫,佐々木成子,松村徹,山本潤,石塚真由美,宮下ちひろ,池野多美子,荒木敦子,岸玲子
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] ダイオキシン類曝露と胎児発育との関連: 遺伝的なリスクについて―北海道スタディ2015

    • Author(s)
      小林澄貴,宮下ちひろ,佐々木成子,荒木敦子,佐田文宏,坂晋,梶原淳睦,戸高尊,岸玲子.
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 児の出生体重と母親の社会経済要因との関連についての疫学研究―北海道スタディ2015

    • Author(s)
      田村菜穂美,伊藤久美子,花岡知之,喜多歳子,西原進吉,宮下ちひろ,荒木敦子,小笠原克彦,岸玲子
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 有機塩素系農薬が乳幼児の免疫に与える影響―環境と子どもの健康北海道スタディー2015

    • Author(s)
      宮下ちひろ,金澤文子,佐々木成子,池野多美子,荒木敦子,伊藤佐智子,小林祥子,水谷太,苣木洋一,岸玲子
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胎児期の有機塩素系農薬曝露が6か月児の精神運動発達に及ぼす影響-北海道スタディ2015

    • Author(s)
      山﨑圭子,宮下ちひろ,中島そのみ, 池野多美子,荒木敦子,伊藤佐智子, 小林祥子,水谷太,苣木洋一,岸玲子
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 出生コホート研究で明らかになった人への環境ホルモン様作用2014

    • Author(s)
      岸玲子
    • Organizer
      第17回環境ホルモン学会
    • Place of Presentation
      東京大学山上会館(東京都・文京区)
    • Year and Date
      2014-12-09 – 2014-12-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] ビスフェノールAの胎児期曝露による出生体格,臍帯血中ホルモン濃度,神経発達への影響.2014

    • Author(s)
      湊屋街子,佐々木成子,中島そのみ,山本潤,荒木敦子,伊藤佐智子,宮下ちひろ,松村徹,野々村克也,三井貴彦,長和俊,岸玲子
    • Organizer
      第17回環境ホルモン学会
    • Place of Presentation
      東京大学山上会館(東京都・文京区)
    • Year and Date
      2014-12-09 – 2014-12-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胎児期の有機塩素系農薬が小児アレルギー発症に与える影響―環境と子どもの健康北海道スタディー2014

    • Author(s)
      宮下ちひろ,金澤文子,池野多美子,荒木敦子,伊藤佐智子,小林澄貴,湊屋街子,Houman Goudarzi,小林祥子,田村菜穂美,水谷太,苣木洋一,岸玲子
    • Organizer
      第66回北海道公衆衛生学会
    • Place of Presentation
      北海道大学 学術交流会館(北海道・札幌市)
    • Year and Date
      2014-12-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胎児期の母の受動喫煙が児の出生時体格に及ぼす影響: 遺伝環境交互作用について.2014

    • Author(s)
      小林澄貴, 佐々木成子, 佐田文宏, 宮下ちひろ, 池野多美子, 荒木敦子, 岸玲子
    • Organizer
      第66回北海道公衆衛生学会
    • Place of Presentation
      北海道大学 学術交流会館(北海道・札幌市)
    • Year and Date
      2014-12-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] Hokkaido Study on Environment and Children’s Health: Cohort profile and findings of perinatal Perfluoroalkyl acid (PFAAs)exposure and various health outcomes.2014

    • Author(s)
      Reiko Kishi, Atsuko Araki
    • Organizer
      2014 Conference of International Society for Environmental Epidemiology Asia Chapter
    • Place of Presentation
      Xinhua Hospital, Shanghai, China
    • Year and Date
      2014-11-30 – 2014-12-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effects of prenatal bisphenol A exposure on birth weight, sex hormone levels and mental and motor development.2014

    • Author(s)
      Minatoya M, Sasaki S, Nakajima S, Yamamoto J, Araki A, Ito S, Miyashita C, Matsumura T, Nonomura K, Mitsui T, Cho K, Kishi R.
    • Organizer
      2014 Conference of International Society for Environmental Epidemiology Asia Chapter
    • Place of Presentation
      Xinhua Hospital, Shanghai, China
    • Year and Date
      2014-11-30 – 2014-12-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] 空間周波数特性が表情変化におけるN170に与える影響と自閉症傾向の関係に関する検討2014

    • Author(s)
      日高茂暢,諸冨隆,室橋春光
    • Organizer
      日本臨床神経生理学会第44回大会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] Perinatal PFAAs Exposure Cause Various Health Outcomes on Offspring Including Effects on Reproductive and Thyroid Hormones: The Hokkaido Study.2014

    • Author(s)
      Reiko Kishi, Atsuko Araki, Sachiko Itoh, Chihiro Miyashita, Houman Goudarzi, Sachiko Kobayashi, Seiko Sasaki, Ikuko Kashino, H Nakazawa, Tamie Nakajima, Takahiko Mitsui, Katsuya Nonomura
    • Organizer
      PPTOX IV
    • Place of Presentation
      Boston Marriott long Wharf Hotel, Boston, MA, USA
    • Year and Date
      2014-10-26 – 2014-10-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 北海道における妊婦の職域における化学物質曝露・受動喫煙および飲酒習慣が児の出生時体格に及ぼす影響2014

    • Author(s)
      小林澄貴, 荒木敦子, 宮下ちひろ, 池野多美子, 伊藤佐智子, 伊藤久美子, Goudarzi Houman, 田村菜穂美, 岸玲子
    • Organizer
      平成26年度日本産業衛生学会北海道地方会
    • Place of Presentation
      札幌市医師会館(北海道・札幌市)
    • Year and Date
      2014-10-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Twelve years of progress in the Hokkaido birth cohort study on environment and children's health: malformation, development and allergy.2014

    • Author(s)
      Kishi R
    • Organizer
      International Symposium of Environmental Medicine Program
    • Place of Presentation
      National Taiwan university College of Public Health, Taipei, Taiwan.
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Twelve Years of Progress in the Hokkaido Birth Cohort Study on Environment and Children's Health: Focused on Dioxins and PFCs.2014

    • Author(s)
      Kishi R
    • Organizer
      Summit on Child Health and the Environment 2014.
    • Place of Presentation
      Hong Kong Academy of Medicine Building, Hong Kong, China.
    • Year and Date
      2014-10-11 – 2014-10-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dioxins and PCBs concentrations in umbilical cord blood collected in Hokkaidou, Japan2014

    • Author(s)
      Jumboku Kajiwara, Takashi Todaka, Hironori Hirakawa, Takashi Miyawaki, Tamiko Ikeno, Cihiro Miyasita, Sachiko Itoh, Seiko Sasaki, Reiko KIshi, Masutaka Furue
    • Organizer
      34TH INTERNATIONAL SYMPOSIUM HALOGENATED PERSISTENT ORGANIC POLLUTANTS
    • Place of Presentation
      Melia Castilla Hotel, Madrid,Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Polychlorinated biphenyls concentrations in blood of Yusho patients during medical check-ups performed in 20122014

    • Author(s)
      Miyawaki T, Todaka T, Hirakawa H, Hori T, Kajiwara J, Hirata T, Uchi H, Furue M
    • Organizer
      34TH INTERNATIONAL SYMPOSIUM HALOGENATED PERSISTENT ORGANIC POLLUTANTS
    • Place of Presentation
      Melia Castilla Hotel, Madrid,Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Concentration of Dechlorane Plus in fish samples collected in Kyushu district, western Japan2014

    • Author(s)
      Hori Tsuguhide, Takashi Miyawaki, Koji Takahashi, Daisuke Yasutake, Takamitsu Yamamoto, Jumboku Kajiwara, Takahiro Watanabe
    • Organizer
      34TH INTERNATIONAL SYMPOSIUM HALOGENATED PERSISTENT ORGANIC POLLUTANTS
    • Place of Presentation
      Melia Castilla Hotel, Madrid,Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Determination of hexabromocyclododecane in fish samples collected from Japanese markets2014

    • Author(s)
      Koji Takahashi, Tsuguhide Hori, Jumboku Kajiwara, Takahiro Watanabe
    • Organizer
      34TH INTERNATIONAL SYMPOSIUM HALOGENATED PERSISTENT ORGANIC POLLUTANTS
    • Place of Presentation
      Melia Castilla Hotel, Madrid,Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Exposure levels of perfluoroalkyl acids and their effects on children's health - Hokkaido study. 26th Annual International Society for Environmental Epidemiology Conference - From Local to Global2014

    • Author(s)
      Kishi R
    • Organizer
      Advancing Science for Policy in Environmental Health.
    • Place of Presentation
      University of Washington, Seattle, USA
    • Year and Date
      2014-08-24 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Exposure to perfluoroalkyl chemicals and neurodevelopment at 6 months of age2014

    • Author(s)
      Goudarzi H., Ikeno T., Kobayashi S., Araki A., Miyashita C., Sasaki S., Nakajima S., Nakazawa H., Kishi R.
    • Organizer
      26th Annual International Society for Environmental Epidemiology Conference - From Local to Global: Advancing Science for Policy in Environmental Health.
    • Place of Presentation
      University of Washington, Seattle, USA
    • Year and Date
      2014-08-24 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Association between maternal exposure to di(2-ethylhexyl) phthalate and sex hormone levels in fetal blood.2014

    • Author(s)
      Araki A., Mitsui T., Miyashita C., Nakajima T., Nakazawa H., Sasaki S., Ikeno T., Cho K., Itoh S., Nonomura K., Kishi R.
    • Organizer
      26th Annual International Society for Environmental Epidemiology Conference - From Local to Global: Advancing Science for Policy in Environmental Health
    • Place of Presentation
      University of Washington, Seattle, USA
    • Year and Date
      2014-08-24 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Associations between fetal genetic polymorphisms and cord blood sex hormone and protein levels2014

    • Author(s)
      Sata F., Eto A., Araki A., Mitsui T., Kanatani Y., Kishi R., Nonomura K
    • Organizer
      26th Annual International Society for Environmental Epidemiology Conference - From Local to Global Advancing Science for Policy in Environmental Health.
    • Place of Presentation
      University of Washington, Seattle, USA
    • Year and Date
      2014-08-24 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] The effects of perfluoroalkyl acids (PFAAs) exposure in utero on IGF2/H19 DNA methylation in cord blood.2014

    • Author(s)
      Kobayashi S., Azumi K., Sasaki S., Ishizuka M., Nakazawa H., Okada E., Kobayashi S., Goudarzi H., Itoh S., Miyashita C., Ikeno T., Araki A., Kishi R.
    • Organizer
      26th Annual International Society for Environmental Epidemiology Conference
    • Place of Presentation
      University of Washington, Seattle, USA
    • Year and Date
      2014-08-24 – 2014-08-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] The Association between Parental Socioeconomic Status and Intellectual Ability in Japanese Infants aged 42 month: The Hokkaido Study.2014

    • Author(s)
      Kita T., Nakajima S., Ikeno T., Kishi R.
    • Organizer
      The 20th IEA World Congress Of Epidemiology.
    • Place of Presentation
      Dena’ina Civic and Convention Center, Anchorage, USA
    • Year and Date
      2014-08-17 – 2014-08-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] DEHPへの胎児期曝露による児の性ホルモン濃度への影響2014

    • Author(s)
      荒木敦子, 三井貴彦, 宮下ちひろ, 那須民江, 伊藤佐智子, 佐々木成子, 長和俊, 池野多美子, 野々村克也, 岸玲子
    • Organizer
      第84回 日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-25 – 2015-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 児の出生体重と母親の社会経済要因との関連についての疫学研究2014

    • Author(s)
      田村菜穂美, 伊藤久美子, 小林澄貴, 岡田恵美子, 喜多歳子, Goudarzi Houman, 宮下ちひろ, 荒木敦子, 池野多美子, 岸玲子
    • Organizer
      第84回 日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-25 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] フタル酸エステル類の胎児期曝露による次世代影響に関する疫学研究2014

    • Author(s)
      荒木敦子, 岸玲子
    • Organizer
      第84回 日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-25 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] PFOS. PFOAの胎児期曝露が与える児の出生時性ホルモン濃度への影響2014

    • Author(s)
      伊藤佐智子, 荒木敦子, 宮下ちひろ, 中澤裕之, 三井貴彦, 長和俊, 佐々木成子, 池野多美子, 野々村克也, 岸玲子
    • Organizer
      第84回 日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-25 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胎児期ビスフェノールA曝露による臍帯血中性ホルモン濃度への影響2014

    • Author(s)
      佐々木成子, 山本潤, 荒木敦子, 伊藤佐智子, 宮下ちひろ, 三井貴彦, 長和俊, 野々村克也, 松村徹, 岸玲子
    • Organizer
      第84回 日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-25 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 妊婦の受動喫煙が児の出生時体格へ及ぼす影響:遺伝的なハイリスク群について-環境と子どもの健康に関する北海道スタディ2014

    • Author(s)
      小林澄貴, 佐々木成子, 佐田文宏, 宮下ちひろ, 池野多美子, 荒木敦子, 岸玲子
    • Organizer
      北海道小児保健研究会 平成26年度総会
    • Place of Presentation
      札幌医科大学(北海道・札幌市)
    • Year and Date
      2014-05-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 血液中PCB濃度のクロスチェック2014

    • Author(s)
      梶原 淳睦,戸高 尊,平川博仙,堀 就英,小木曽 俊孝,宮脇 崇,飛石 和大,高尾 佳子,平田 輝昭,岸 玲子,古江 増隆
    • Organizer
      第23回環境化学討論会
    • Place of Presentation
      京都大学百周年記念時計台記念館(京都府・京都市)
    • Year and Date
      2014-05-14 – 2014-05-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] Associations between fetal genetic polymorphisms and cord blood sex hormone and protein levels2014

    • Author(s)
      Sata F., Eto A., Araki A., Mitsui T., Kanatani Y., Kishi R., Nonomura K.
    • Organizer
      26th Annual International Society for Environmental Epidemiology Conference - From Local to Global: Advancing Science for Policy in Environmental Health
    • Place of Presentation
      University of Washington(USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 胎児期ビスフェノールA曝露による臍帯血中性ホルモン濃度への影響2014

    • Author(s)
      佐々木成子, 山本潤, 荒木敦子, 伊藤佐智子, 宮下ちひろ, 三井貴彦, 長和俊, 野々村克也, 松村徹, 岸玲子
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] DEHPへの胎児期曝露による児の性ホルモン濃度への影響2014

    • Author(s)
      荒木敦子, 三井貴彦, 宮下ちひろ, 田川雅史, 中島民江, 伊藤佐智子, 佐々木成子, 長和俊, 池野多美子,野々村克也, 岸玲子
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] PFOS・PFOAの胎児期曝露が与える児の出生時性ホルモン濃度への影響2014

    • Author(s)
      伊藤佐智子, 荒木敦子, 宮下ちひろ, 中澤裕之, 三井貴彦, 長和俊, 佐々木成子, 池野多美子, 野々村克也, 岸玲子
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Association Between Prenatal Exposure to Perfluoroalkyl Substances (PFAS) and Reduced Birth Weight: Is Glomerular Filtration Rate the Underlying Cause?2014

    • Author(s)
      Verner MA., Loccisano AE., Yoon M., Wu H., McDougall R., Maisonet M., Marcus M., Kishi R., Miyashita C., Chen MH., Hsieh W., Andersen M., Clewell III H., Longnecker MP
    • Organizer
      SOT's 53rd Annual Meeting
    • Place of Presentation
      Phoenix Convention Center(USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 妊婦葉酸値と8歳時ADHD関連症状の関係:環境と子どもの健康に関する北海道スタディ2013

    • Author(s)
      池野多美子, 喜多歳子, 小林澄貴, 岸玲子
    • Organizer
      第65回北海道公衆衛生学会
    • Place of Presentation
      札幌市生涯学習センターちえりあ(札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Prenatal Perfluorinated Compounds Exposure and Early childhood Health2013

    • Author(s)
      Kishi R.
    • Organizer
      DOHaD2013-8th World Congress on DOHaD
    • Place of Presentation
      SUNTEC Singapore Convention & Exhibition Centre(Singapore)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Maternal exposure to dehp and sex hormone levels in cord blood2013

    • Author(s)
      Araki A., Mitsui T., Miyashita C., Tagawa M., Nakajima T., Sasaki S., Ikeno T., Itoh S., Okada E., Cho K., Nonomura K., Kishi R.
    • Organizer
      DOHaD2013-8th World Congress on DOHaD
    • Place of Presentation
      SUNTEC Singapore Convention & Exhibition Centre(Singapore)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 8歳の注意欠損多動性障害に関する要因-環境と子どもの健康に関する北海道スタディ-2013

    • Author(s)
      池野多美子, 小林澄貴, 喜多歳子, 中島そのみ, 岸玲子
    • Organizer
      第72回日本公衆衛生学会総会
    • Place of Presentation
      三重県総合文化センター(津市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 親の世帯収入と48か月児の知的能力(K-ABC)との関連;環境と子どもの健康に関する前向きコホート研究(北海道スタディ)の結果2013

    • Author(s)
      喜多歳子, 池野多美子, 中島そのみ, 小林澄貴, 岸玲子
    • Organizer
      第72回日本公衆衛生学会総会
    • Place of Presentation
      三重県総合文化センター(津市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fetal genetic polymorphisms associated with estrogen levels and sex-hormone-binding globulin and anthropometric parameters in newborns2013

    • Author(s)
      Eto A., Sata F., Kanatani Y., Araki A., Mitsui T., Kishi R.
    • Organizer
      Environment and Health - Bridging South, North, East and West Conference of ISEE, ISES and ISIAQ
    • Place of Presentation
      Congress Center Basel(Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Presentation] The effects of hydroxylated PCBs in maternal serum on infant thyroid hormones2013

    • Author(s)
      Itoh S., Kajiwara J., Miyashita C., Kobayashi S., Sasaki S., Ban S., Ikeno T., Araki A., Kishi R.
    • Organizer
      Environment and Health - Bridging South, North, East and West Conference of ISEE, ISES and ISIAQ
    • Place of Presentation
      Congress Center Basel(Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Prenatal Exposure to 11 Perfluorinated Compounds (PFCs) and infant weight in the Hokkaido Study on Environmental and Children's Health2013

    • Author(s)
      Kashino I., Okada E., Sasaki S., Miyashita C., Ikeno T., Araki A., Yamamoto J., Matsuura H., Matsumura T., Tamakoshi A., Kishi R.
    • Organizer
      Environment and Health - Bridging South, North, East and West Conference of ISEE, ISES and ISIAQ
    • Place of Presentation
      Congress Center Basel(Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Relationship between prenatal exposure to perfluorinated compounds and allergic diseases in infants2013

    • Author(s)
      Okada E., Kashino I., Sasaki S., Miyashita C., Ikeno T., Araki A., Yamamoto J., Matsuura H., Matsumura T., Tamakoshi A., Kishi R.
    • Organizer
      Environment and Health - Bridging South, North, East and West Conference of ISEE, ISES and ISIAQ
    • Place of Presentation
      Congress Center Basel(Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fetal genetic polymorphisms associated with estrogen levels and sex-hormone-binding globulin and fetal growth restriction2013

    • Author(s)
      Sata F., Eto A., Kanatani Y., Araki A., Mitsui T., Kishi R., Nonomura K.
    • Organizer
      Environment and Health - Bridging South, North, East and West Conference of ISEE, ISES and ISIAQ
    • Place of Presentation
      Congress Center Basel(Switzerland)
    • Related Report
      2013 Annual Research Report
  • [Book] 地球社会の環境ビジョン-これからの環境学-, 市民協力による環境疫学研究-わが国で初の本格的出生コーホート研究の経験から学ぶ-2013

    • Author(s)
      岸玲子(著), 毛利衛(編), 進士五十八(編)
    • Publisher
      財団法人 日本学術協力財団
    • Related Report
      2013 Annual Research Report
  • [Book] 睡眠中にみられるてんかん発作:発達期 「睡眠医療」Vol.7 No.22013

    • Author(s)
      白石秀明(著), 千葉茂(編)
    • Publisher
      ライフサイエンス
    • Related Report
      2013 Annual Research Report
  • [Remarks] 北海道大学 環境健康科学教育研究センター 研究業績

    • URL

      http://www.cehs.hokudai.ac.jp/research/yearly/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 環境と健康ひろば

    • URL

      http://www.cehs.hokudai.ac.jp/hiroba/

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
  • [Remarks] 環境と子どもに関する研究・北海道スタディ

    • URL

      http://www.cehs.hokudai.ac.jp/hokkaidostudy/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 北海道大学 環境健康科学研究教育センター 研究業績

    • URL

      http://www.cehs.hokudai.ac.jp/research/yearly/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 環境健康科学研究教育センター 研究業績

    • URL

      http://www.cehs.hokudai.ac.jp/research/yearly/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 環境と健康ひろば

    • URL

      http://www.cehs.hokudai.ac.jp/hiroba/

    • Related Report
      2013 Annual Research Report

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Published: 2013-05-15   Modified: 2019-07-29  

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