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Molecular elucidation of sensory-dependent control of bone metabolism and its clinical application

Research Project

Project/Area Number 25253090
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionTokyo Medical and Dental University

Principal Investigator

TAKEDA Shu  東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30376727)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥44,720,000 (Direct Cost: ¥34,400,000、Indirect Cost: ¥10,320,000)
Fiscal Year 2015: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2014: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2013: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Keywords骨代謝学
Outline of Final Research Achievements

We demonstrated that Sema3A, a prototype of chemo-repellent, regulates sensory innervation into bone tissue, which in turn orchestrates the normal bone remodeling and sensory nerves are essential for normal bone regeneration.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (85 results)

All 2016 2015 2014 2013 Other

All Journal Article (14 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 14 results,  Open Access: 2 results,  Acknowledgement Compliant: 7 results) Presentation (44 results) (of which Int'l Joint Research: 2 results,  Invited: 35 results) Book (27 results)

  • [Journal Article] Circadian Clock Regulates Bone Resorption in Mice. Circadian Clock Regulates Bone Resorption in Mice.2016

    • Author(s)
      Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, Hinoi E, Okawa A, Takeda S.
    • Journal Title

      J Bone Miner Res.

      Volume: - Issue: 7 Pages: 1344-1355

    • DOI

      10.1002/jbmr.2803

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Loss of Osteoblast Runx3 Produces Severe Congenital Osteopenia.2015

    • Author(s)
      Bauer, O., Sharir, A., Kimura, A., Hantisteanu, S., Takeda, S., Groner, Y.
    • Journal Title

      Mol Cell Biol

      Volume: 35 Issue: 7 Pages: 1097-109

    • DOI

      10.1128/mcb.01106-14

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] MicroRNA-145 regulates osteoblastic differentiation by targeting the transcription factor Cbfb.2015

    • Author(s)
      Fukuda T, Ochi H, Sunamura S, Haiden A, Bando W, Inose H, Okawa A, Asou Y, Takeda S.
    • Journal Title

      FEBS Lett.

      Volume: 589 Issue: 21 Pages: 3302-8

    • DOI

      10.1016/j.febslet.2015.09.024

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Cdc42 is critical for cartilage development during endochondral ossification.2015

    • Author(s)
      Suzuki W, Yamada A, Aizawa R, Suzuki D, Kassai H, Harada T, Nakayama M, Nagahama R, Maki K, Takeda S, Yamamoto M, Aiba A, Baba K, Kamijo R
    • Journal Title

      Endocrinology

      Volume: 156 Issue: 1 Pages: 314-322

    • DOI

      10.1210/en.2014-1032

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Genetic determination of the cellular basis of the ghrelin-dependent bone remodeling.2015

    • Author(s)
      Chengshan Ma, Toru Fukuda, Hiroki Ochi, Satoko Sunamura, Cheng Xu, Ren Xu, Atsushi Okawa, Shu Takeda
    • Journal Title

      Mol Metab

      Volume: 4 Issue: 3 Pages: 175-185

    • DOI

      10.1016/j.molmet.2015.01.002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The Two Sides of Vitamin E Supplementation.2014

    • Author(s)
      Ochi H, Takeda S.
    • Journal Title

      Gerontology

      Volume: - Issue: 4 Pages: 319-26

    • DOI

      10.1159/000366419

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proteomics-based identification of novel proteins in temporal tendons of patients with masticatory muscle tendon--aponeurosis hyperplasia.2014

    • Author(s)
      Nakamoto, A., Sato, T., Hirosawa, N., Nakamoto, N., Enoki, Y., Chida, D., Usui, M., Takeda, S., Nagai, T., Sasaki, A., Sakamoto, Y., and Yoda, T
    • Journal Title

      Int J Oral Maxillofac Surg

      Volume: 43 Pages: 113-119

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.2014

    • Author(s)
      Mizuha Akiyama, Rie Wada, Kohei Inagawa, Takahiko Nishiyama, Ruri Kaneda, Toru Fukuda, Shu Takeda, Shugo Tohyama, Hisayuki Hashimoto, Yoshifumi Kawamura, Naoki Goshima, Ryo Aeba, Hiroyuki Yamagishi, Keiichi Fukuda, Masaki Ieda
    • Journal Title

      EMBO J.

      Volume: 33 Issue: 14 Pages: 1565-1581

    • DOI

      10.15252/embj.201387605

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.2014

    • Author(s)
      Matsumoto, Masahiko Okubo, Keisuke Nakashima, Masayuki Yamato, Teruo Okano, Toru Fukuda, Dai Chida, Yuuki Imai, Hisataka Yasuda, Tatsuji Nishihara, Masumi Akita, Hiromi Oda, Yasushi Okazaki, Tatsuo Suda, Tetsuya Yoda
    • Journal Title

      FEBS Lett.

      Volume: 588 Issue: 14 Pages: 2262-2269

    • DOI

      10.1016/j.febslet.2014.05.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Sema3A regulates bone-mass accrual through sensory innervations.2013

    • Author(s)
      Fukuda, T., Takeda, S., Xu, R., Ochi, H., Sunamura, S., Sato, T., Shibata, S., Yoshida, Y., Gu, Z., Kimura, A., Ma, C., Xu, C., Bando, W., Fujita, K., Shinomiya, K., Hirai, T., Asou, Y., Enomoto, M., Okano, H., Okawa, A., and Itoh, H.
    • Journal Title

      Nature

      Volume: 497 Pages: 490-3

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice.2013

    • Author(s)
      Takarada, T., Hinoi, E., Nakazato, R., Ochi, H., Xu, C., Tsuchikane, A., Takeda, S., Karsenty, G., Abe, T., Kiyonari, H., and Yoneda, Y.
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 28 Pages: 2064-2069

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling.2013

    • Author(s)
      Piao, J., Tsuji, K., Ochi, H., Iwata, M., Koga, D., Okawa, A., Morita, S., Takeda, S., and Asou, Y.
    • Journal Title

      Sci Rep

      Volume: 3 Pages: 3022-3022

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Role of Individual Domains and the Significance of Shedding of ATP6AP2/(pro)renin Receptor in Vacuolar H(+)-ATPase Biogenesis.2013

    • Author(s)
      Kinouchi, K., Ichihara, A., Sano, M., Sun-Wada, G.H., Wada, Y., Ochi, H., Fukuda, T., Bokuda, K., Kurosawa, H., Yoshida, N., Takeda, S., Fukuda, K., and Itoh, H.
    • Journal Title

      PLoS One

      Volume: 8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhancement of fracture healing by electrical stimulation in the comminuted intraarticular fracture of distal radius.2013

    • Author(s)
      Kohata, K., Itoh, S., Takeda, S., Kanai, M., Yoshioka, T., Suzuki, H., and Yamashita, K.
    • Journal Title

      Bio-Medical Materials and Engineering

      Volume: 23 Pages: 485-493

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 骨と全身のネットワークによる代謝調節機構2015

    • Author(s)
      竹田 秀
    • Organizer
      第49回日本小児内分泌学会学術集会
    • Place of Presentation
      タワーホール船場、東京都江戸川区
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] グレリンは骨芽細胞に作用し骨形成を促進する2015

    • Author(s)
      越智 広樹、馬 成山、福田 亨、砂村 聡子、大川 淳、竹田 秀
    • Organizer
      第36回日本肥満学会
    • Place of Presentation
      名古屋国際会議場、愛知県名古屋市
    • Year and Date
      2015-10-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] CKD MBDの病態と治療-骨折予防を目指した治療とは-2015

    • Author(s)
      竹田 秀
    • Organizer
      第45回日本腎臓学会東部学術大会ランチョンセミナー9
    • Place of Presentation
      東京ミッドタウン、東京都港区
    • Year and Date
      2015-10-03
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 骨粗鬆症治療における新たな視点-骨と全身の臓器ネットワーク-2015

    • Author(s)
      竹田 秀
    • Organizer
      第33回日本骨代謝学会学術集会ランチョンセミナー
    • Place of Presentation
      京王プラザホテル、東京都新宿区
    • Year and Date
      2015-07-25
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 医歯学融合集学的骨転移診療体制の確立と骨転移早期発見の取り組み2015

    • Author(s)
      佐藤信吾、澤村千草、松本誠一、竹田秀、大川淳
    • Organizer
      第48回日本整形外科学会 骨・軟部腫瘍学術集会
    • Place of Presentation
      かがわ国際会議場、香川県高松市
    • Year and Date
      2015-07-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] Regulation of whole body metabolism by bone-interorgan communication2015

    • Author(s)
      竹田 秀
    • Organizer
      第47回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      仙台国際センター、宮城県仙台市
    • Year and Date
      2015-07-10
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 臓器間ネットワーク2015

    • Author(s)
      竹田 秀
    • Organizer
      第1回日本骨免疫学会
    • Place of Presentation
      ホテルブリーズベイマリーナ、沖縄県宮古島市
    • Year and Date
      2015-07-02
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 骨と全身のネットワークによる代謝調節機構2015

    • Author(s)
      竹田 秀
    • Organizer
      2015年骨形態フォーラムin伊香保
    • Place of Presentation
      石坂旅館、群馬県渋川市
    • Year and Date
      2015-06-27
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 糖尿病・エネルギー代謝からみた骨と多臓器連関2015

    • Author(s)
      竹田 秀
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      海峡メッセ下関、山口県下関市
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Vitamin E and bone2015

    • Author(s)
      Shu Takeda
    • Organizer
      2015 SICEM
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-05-01
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Regulation of bone remodelling by semaphorins and sensory innervations2015

    • Author(s)
      Shu Takeda
    • Organizer
      4th Joint Meeting of ECTS and IBMS
    • Place of Presentation
      Rotterdam, The Netherlands
    • Year and Date
      2015-04-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] グレリンは骨芽細胞に作用し骨形成を促進する2015

    • Author(s)
      越智広樹、馬 成山、福田 亨、砂村聡子、大川 淳、竹田 秀
    • Organizer
      第52回日本臨床分子医学会学術集会
    • Place of Presentation
      みやこめっせ、京都府京都市
    • Year and Date
      2015-04-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 脳と骨のクロストーク2015

    • Author(s)
      竹田 秀
    • Organizer
      第52回日本臨床分子医学会学術集会
    • Place of Presentation
      みやこめっせ、京都府京都市
    • Year and Date
      2015-04-10
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Control of bone remodeling by interorgan communication2014

    • Author(s)
      竹田 秀
    • Organizer
      Crest International Symposium on Homeodynamics during Development and Diseases
    • Place of Presentation
      八芳園(東京)
    • Year and Date
      2014-12-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 骨代謝制御機構に関する最近の進歩2014

    • Author(s)
      竹田 秀
    • Organizer
      第24回臨床内分泌代謝Update
    • Place of Presentation
      大宮ソニックシティ(大宮市、埼玉県)
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 神経系による骨代謝調節2014

    • Author(s)
      竹田 秀
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市、神奈川県)
    • Year and Date
      2014-11-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Implication of Vitamin E in Bone Metabolism.2014

    • Author(s)
      Shu Takeda
    • Organizer
      IOF Reagionals Taipei 2014 5th Asia -Pacific Osteoporosis Meeting.
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2014-11-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる骨代謝調節機構2014

    • Author(s)
      竹田 秀
    • Organizer
      第1回六甲医学研究会
    • Place of Presentation
      六甲山ホテル(神戸市、兵庫県)
    • Year and Date
      2014-11-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] 骨代謝の中枢性制御-中枢と末梢のクロストーク2014

    • Author(s)
      竹田 秀
    • Organizer
      第41回日本神経内分泌学会学術集会
    • Place of Presentation
      都道府県会館(東京)
    • Year and Date
      2014-11-02
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 骨を基軸とした臓器間ネットワークによる代謝調節機構-骨は全身の司令塔?-2014

    • Author(s)
      竹田 秀
    • Organizer
      第29回日本女性医学学会学術集会
    • Place of Presentation
      都市センターホテル(東京)
    • Year and Date
      2014-11-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Control of bone remodeling by interorgan network2014

    • Author(s)
      竹田 秀
    • Organizer
      第16回日本骨粗鬆症学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-10-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 骨粗鬆症の病態に関するupdate2014

    • Author(s)
      竹田 秀
    • Organizer
      第16回日本骨粗鬆症学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-10-23
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる骨代謝調節機構2014

    • Author(s)
      竹田秀
    • Organizer
      第5回Molecular Cardiovascular Conference II
    • Place of Presentation
      神戸市、兵庫県
    • Year and Date
      2014-09-05
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] カレントコンセプト: Over View:骨による多臓器制御機構「オステオネットワーク」2014

    • Author(s)
      竹田秀
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市、大阪府)
    • Year and Date
      2014-07-24
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] グレリンは骨芽細胞に作用し、骨形成を促進する2014

    • Author(s)
      越智広樹、馬成山、福田亨、砂村聡子、大川淳、竹田秀
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市、大阪府)
    • Year and Date
      2014-07-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 血管内皮細胞より産生されるnetrin-4は破骨細胞分化を抑制し骨粗鬆症の発症を予防する2014

    • Author(s)
      佐藤毅、榎本祐一郎、大久保正彦、古株彰一郎、臼井通彦、竹田秀、依田哲也
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市、大阪府)
    • Year and Date
      2014-07-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cdc42は軟骨形成とそれに続く軟骨内骨化に必須である2014

    • Author(s)
      鈴木航、山田篤、相澤怜、鈴木大、竹田秀、山本松男、馬場一美、上條竜太郎
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市、大阪府)
    • Year and Date
      2014-07-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] 骨を中心とした臓器ネットワークによる代謝調節機構2014

    • Author(s)
      竹田秀
    • Organizer
      第1回日本骨免疫会議
    • Place of Presentation
      万国津梁館(那覇市、沖縄県)
    • Year and Date
      2014-07-04
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 神経と骨のネットワークによる代謝調節2014

    • Author(s)
      竹田秀、田中栄
    • Organizer
      第34回日本骨形態計測学会、カレントコンセプト「骨の臨床・基礎研究のトピックス」
    • Place of Presentation
      さっぽろ芸文館(札幌市、北海道)
    • Year and Date
      2014-06-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] How does Sema3A regulate bone?2014

    • Author(s)
      Shu Takeda
    • Organizer
      2014 Seoul International Congress of Endocrinology and Metabolism(SICEM)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-05-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 神経と骨のネットワークによる代謝調節2014

    • Author(s)
      竹田秀
    • Organizer
      第51回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2014-04-12
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Control of bone remodeling by organ-network

    • Author(s)
      竹田秀
    • Organizer
      Molecular mechanism in bone and tooth, its clinical implicationシンポジウム
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨代謝の新たな調節機構—臓器連関における骨の意義—

    • Author(s)
      竹田秀
    • Organizer
      第43回 新潟腎カンファランス
    • Place of Presentation
      新潟
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる新たな骨代謝調節機構

    • Author(s)
      竹田秀
    • Organizer
      第15回 日本骨粗鬆症学会
    • Place of Presentation
      大阪
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨粗鬆症の新たな治療戦略~ステロイド性骨粗鬆症における骨形成促進剤の位置付け~

    • Author(s)
      竹田秀
    • Organizer
      ステロイド性骨粗鬆症 臨床セミナー
    • Place of Presentation
      つくば
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨代謝の新たな調節機構-臓器連関における骨の意義

    • Author(s)
      竹田秀
    • Organizer
      横浜市立みなと赤十字病院セミナー
    • Place of Presentation
      横花
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 粗鬆症の病態と治療

    • Author(s)
      竹田秀
    • Organizer
      埼玉県南部 骨・関節疾患フォーラム
    • Place of Presentation
      川口
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる新たな骨代謝調節機構

    • Author(s)
      竹田秀
    • Organizer
      第31回 小児代謝性骨疾患研究会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる骨代謝調節

    • Author(s)
      竹田秀
    • Organizer
      第6回 彩の国骨フォーラム
    • Place of Presentation
      埼玉県毛呂
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる骨代謝制御

    • Author(s)
      竹田秀
    • Organizer
      第1回 東京未来医療フォーラム
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 臓器ネットワークによる骨代謝制御 ー全身疾患としての骨粗鬆症ー

    • Author(s)
      竹田秀
    • Organizer
      第26回北海道骨粗鬆症研究会
    • Place of Presentation
      札幌
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨を基軸とした代謝ネットワーク機構

    • Author(s)
      竹田秀
    • Organizer
      第43回 日本心脈管作動物質学会
    • Place of Presentation
      神戸
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨粗鬆症の病態と治療 ー治療薬の使い分けー

    • Author(s)
      竹田秀
    • Organizer
      第5回二州骨粗鬆症研究会
    • Place of Presentation
      敦賀市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 骨代謝の新たな調節機構

    • Author(s)
      竹田秀
    • Organizer
      第86回京都内分泌同好会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] 「解明」から「制御」へ 肥満症のメディカルサイエンス2016

    • Author(s)
      越智広樹、竹田 秀
    • Total Pages
      212
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report
  • [Book] オックスフォード生理学 原書4版2016

    • Author(s)
      竹田 秀
    • Total Pages
      896
    • Publisher
      丸善出版
    • Related Report
      2015 Annual Research Report
  • [Book] 骨ペディア2015

    • Author(s)
      竹田 秀
    • Total Pages
      328
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report
  • [Book] 骨ペディア2015

    • Author(s)
      竹田 秀、福田 亨
    • Total Pages
      328
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report
  • [Book] 骨ペディア2015

    • Author(s)
      越智広樹、竹田 秀
    • Total Pages
      328
    • Publisher
      羊土社
    • Related Report
      2015 Annual Research Report
  • [Book] ファーマナビゲーター 糖尿病と骨代謝編2015

    • Author(s)
      竹田 秀
    • Total Pages
      356
    • Publisher
      メディカルレビュー社
    • Related Report
      2015 Annual Research Report
  • [Book] Bone and Calcium Research Update 2015. Metabolic crosstalk bone and other organs.2015

    • Author(s)
      Hiroki Ochi, Shu Takeda
    • Total Pages
      10
    • Publisher
      Clin Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] 骨による糖・エネルギー代謝調節2015

    • Author(s)
      越智 広樹, 竹田 秀
    • Total Pages
      5
    • Publisher
      Bio Clinica
    • Related Report
      2014 Annual Research Report
  • [Book] ビタミンの過剰症2015

    • Author(s)
      藤田 浩二、 竹田 秀
    • Total Pages
      4
    • Publisher
      ファルマシア
    • Related Report
      2014 Annual Research Report
  • [Book] 骨代謝の調節機構2014

    • Author(s)
      竹田 秀
    • Total Pages
      8
    • Publisher
      日本腎臓学会誌
    • Related Report
      2014 Annual Research Report
  • [Book] The Two Sides of Vitamin E Supplementation.2014

    • Author(s)
      Hiroki Ochi, Shu Takeda
    • Total Pages
      8
    • Publisher
      Gerontology
    • Related Report
      2014 Annual Research Report
  • [Book] Updates on Lifestyle-Related Diseases and Bone Metabolism. Bidirectional relationship between lifestyle-related diseases and bone metabolism.2014

    • Author(s)
      Shingo Sato, Shu Takeda
    • Total Pages
      8
    • Publisher
      Clin Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] Regulation of bone metastasis by microRNAs.2014

    • Author(s)
      Shingo Sato, Shu Takeda
    • Total Pages
      7
    • Publisher
      Clin Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] Bone metabolism and cardiovascular function update. Nerve system and mutual interaction between bone and blood vessel.2014

    • Author(s)
      越智 広樹, 竹田 秀
    • Total Pages
      7
    • Publisher
      Clin Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] Sema3Aによる骨代謝調節機構.2014

    • Author(s)
      福田 亨, 竹田 秀
    • Total Pages
      5
    • Publisher
      内分泌・糖尿病・代謝内科
    • Related Report
      2014 Annual Research Report
  • [Book] 病因、病態の最新の知見-感覚神経系による骨代謝調節機構.2014

    • Author(s)
      福田 亨, 竹田 秀
    • Total Pages
      5
    • Publisher
      整形外科
    • Related Report
      2014 Annual Research Report
  • [Book] ビタミンEによる骨代謝調節の分子機構.2014

    • Author(s)
      藤田 浩二, 竹田 秀
    • Total Pages
      5
    • Publisher
      腎と骨代謝
    • Related Report
      2014 Annual Research Report
  • [Book] 骨と神経.2014

    • Author(s)
      福田 亨,竹田 秀
    • Total Pages
      6
    • Publisher
      腎と骨代謝
    • Related Report
      2014 Annual Research Report
  • [Book] 抗RANKL抗体.2014

    • Author(s)
      竹田 秀
    • Total Pages
      1
    • Publisher
      医学の歩み
    • Related Report
      2014 Annual Research Report
  • [Book] 神経系による骨代謝制御.2014

    • Author(s)
      福田 亨,竹田 秀
    • Total Pages
      6
    • Publisher
      医学の歩み
    • Related Report
      2014 Annual Research Report
  • [Book] 神経による骨組織改変.2014

    • Author(s)
      竹田 秀
    • Total Pages
      5
    • Publisher
      実験医学
    • Related Report
      2014 Annual Research Report
  • [Book] 骨粗鬆症.2014

    • Author(s)
      竹田 秀
    • Total Pages
      2
    • Publisher
      内科
    • Related Report
      2014 Annual Research Report
  • [Book] 骨代謝の多臓器連関2014

    • Author(s)
      越智 広樹, 竹田 秀
    • Total Pages
      10
    • Publisher
      Clinical Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] ビタミンEと骨代謝2014

    • Author(s)
      越智 広樹, 竹田 秀
    • Total Pages
      2
    • Publisher
      Medical Science Digest
    • Related Report
      2014 Annual Research Report
  • [Book] 神経系と骨・血管連関2014

    • Author(s)
      越智 広樹, 竹田 秀
    • Total Pages
      7
    • Publisher
      Clinical Calcium
    • Related Report
      2014 Annual Research Report
  • [Book] インタビュー:健康な骨と神経のネットワーク~骨代謝メカニズムを解明する~.2014

    • Author(s)
      竹田 秀
    • Total Pages
      3
    • Publisher
      FOOD STYLE21
    • Related Report
      2014 Annual Research Report
  • [Book] 【骨研究最前線】骨形成のメカニズム2013

    • Author(s)
      竹田秀
    • Publisher
      NTS
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-05-15   Modified: 2019-07-29  

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