Development of a graphical model and a tolerance region for the assessment of physiological process and ecological diversity
| Project/Area Number |
25280006
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Statistical science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Kitada Shuichi 東京海洋大学, 海洋科学技術研究科, 教授 (10262338)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | 医薬生物・ゲノム解析 / 生体と生態系の健全性 / 遺伝子ネットワーク / 分子系統樹 / リスク評価 / 医薬生物・ゲノム統計解析 / 影響評価手法 |
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| Outline of Final Research Achievements |
First, we developed a method that constructs the entropy-based maximal core connected subgraph of gene expression profiles. The analysis of the expression profiles at the early developmental stage of Atlantic salmon showed that the resultant graph makes it easy to understand the key players and their interactions. Second, we defined two complementary tolerance intervals. The coverage probability of the standard tolerance interval is at least the pre-specified level, whereas that of the complementary tolerance interval is at most the specified level. With the two complementary tolerance intervals, we developed a statistical procedure to test a target population includes a pre-specified amount of outliers with respect to the reference population. Third, we developed a new index of community diversity. By comparing the species sampling proportion with the value estimated assuming random sampling, it measures phylogenetic skew of member species.
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Report
(4 results)
Research Products
(55 results)
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[Journal Article] Model-based tolerance intervals derived from cumulative historical composition data: Application for substantial equivalence assessment of a genetically modified crop.2014
Author(s)
Hong, B., Fisher, T., Sult, T., Maxwell, C., Mickelson, J., Kishino, H., and Locke, M.
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Journal Title
Journal of Agricultural and Food Chemistry.
Volume: 62
Issue: 40
Pages: 9916-9926
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Comprehensive Comparison of Self-Administered Questionnaires for Measuring Quantitative Autistic Traits in Adults2014
Author(s)
Takeshi Nishiyama, Masako Suzuki, Katsunori Adachi, Satoshi Sumi,Kensuke Okada, Hirohisa Kishino, Saeko Sakai, Yoko Kamio, Masayo Kojima, Sadao Suzuki, Stephen M. Kanne
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Journal Title
Journal of Autism and Developmental Disorders
Volume: 44
Issue: 5
Pages: 993-1007
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Presentation] Phylogenetic skew: A new index of community diversity.2014
Author(s)
Chen, H-Y., Shao, K-T., and Kishino, H.
Organizer
the joint annual meeting of the Society for the Study of Evolution (SSE), the Society of Systematic Biologists (SSB), and the American Society of Naturalists (ASN).
Place of Presentation
Raleigh, USA.
Year and Date
2014-06-20 – 2014-06-24
Related Report
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