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Statistical methodology for stabilizing of the genome-omics data analysis

Research Project

Project/Area Number 25280008
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Statistical science
Research InstitutionThe Institute of Statistical Mathematics

Principal Investigator

Egichi Shinto  統計数理研究所, 数理・推論研究系, 教授 (10168776)

Co-Investigator(Kenkyū-buntansha) 松浦 正明  帝京大学, 公私立大学の部局等, 教授 (40173794)
松井 茂之  名古屋大学, 医学系研究科, 教授 (80305854)
小森 理  福井大学, 学術研究院工学系部門, 講師 (60586379)
間野 修平  統計数理研究所, 数理・推論研究系, 准教授 (20372948)
野間 久史  統計数理研究所, データ科学研究系, 准教授 (70633486)
Co-Investigator(Renkei-kenkyūsha) TAKENOUCHI Takashi  公立はこだて未来大学, システム情報科学部, 准教授 (50403340)
HENMI Masayuki  統計数理研究所, データ科学研究系, 准教授 (80465921)
Research Collaborator COPAS John B.  University of Warwick, Department of Statistics, Emeritus Professor
Huang Su-Yun  Academia Sinica, Institute of Statistical Science
HUNG HUNG  National Taiwan University, Graduate Institute of Epidemiology and Preventive Medicine, Associate Professor
Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2017: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Keywordsオミクス データ / 遺伝子ランキング / データ異質性 / 高次元・小標本 / 準線形モデル / 表現型予測 / 非線形予測 / 準線形回帰モデル / 拡散テンソル画像 / 一般化平均 / 遺伝子発現 / クラスター / 乳がんデータ / ベキエントロピー / ゲノムワイド探索 / 遺伝子発現データ / 群判別問題 / ガンマ・K-平均 / ロバスト クラスタリング / メタラーニング / Itakura-Saitoダイバージェンス / 特徴ベクトル / 2群判別問題 / 線形判別 / ブースティング法 / 符号和統計量 / 個人化治療 / 効果予測
Outline of Final Research Achievements

In genome and omics data analysis we aimed at exploiting new statistical methods to challenge a difficult aspect caused by high-dimensional small-sample observations. In particular, we have proposed and published statistical methods and practical algorithms for prediction for treatment effect and prognosis based on genome and omics data beyond existing methods. In major contributions the subsampling replication method for a gene ranking was presented for a stable ranking, and a new modeling, called quasi-linear model, was proposed to incorporate different linear predictors into an integrated predictor connecting by a generalized mean.

Report

(6 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (129 results)

All 2018 2017 2016 2015 2014 2013

All Journal Article (50 results) (of which Int'l Joint Research: 11 results,  Peer Reviewed: 48 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (62 results) (of which Int'l Joint Research: 24 results,  Invited: 19 results) Book (17 results)

  • [Journal Article] オミクス研究における検証的解析と探索的解析:多重検定とP値を中心に2018

    • Author(s)
      松井茂之
    • Journal Title

      計量生物学

      Volume: 38 Pages: 127-139

    • NAID

      130006742188

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multi-subgroup gene screening using semi-parametric hierarchical mixture models and the optimal discovery procedure: Application to a randomized clinical trial in multiple myeloma2018

    • Author(s)
      Matsui S, Noma H, Qu P, Sakai Y, Matsui K, Heuck C, Crowley J
    • Journal Title

      Biometrics

      Volume: 74 Issue: 1 Pages: 313-320

    • DOI

      10.1111/biom.12716

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A reversal phenomenon in estimation based on multiple samples from the Poisson-Dirichlet distribution2018

    • Author(s)
      Tsukuda K, Mano S
    • Journal Title

      ISM Research Memorandum 1207

      Volume: 20

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Re-assessment of multiple testing strategies for more efficient genome-wide association studies2018

    • Author(s)
      Otani, T., Noma, H., Nishino, J., and Matsui, S.
    • Journal Title

      European Journal of Human Genetics

      Volume: 印刷中

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An optimal semiparametric method for two-group classification2018

    • Author(s)
      Baek, S., Komori, O. Ma, Y.
    • Journal Title

      Scandinavian Journal of Statistics

      Volume: 投稿中

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quasi-linear score for capturing heterogeneous structure in biomarkers2017

    • Author(s)
      Omae K, Komori O, Eguchi S
    • Journal Title

      BMC Bioinformatics

      Volume: 18 Issue: 1 Pages: 1-15

    • DOI

      10.1186/s12859-017-1721-x

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Partition structure and the A-hypergeometric distribution associated with the rational normal curve2017

    • Author(s)
      Shuhei Mano
    • Journal Title

      Electronic Journal of Statistics

      Volume: 11 Issue: 2 Pages: 4452-4487

    • DOI

      10.1214/17-ejs1361

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An efficient and flexible test for rare variant effects2017

    • Author(s)
      Sugasawa, S., Noma, H., Otani, T., Nishino, J. and Matsui, S.
    • Journal Title

      European Journal of Human Genetics

      Volume: 印刷中 Issue: 6 Pages: 19-35

    • DOI

      10.1038/ejhg.2017.43

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Robust bias correction model for estimation of global trend in marine populations2017

    • Author(s)
      Komori, O., Eguchi, S., Saigusa, Y., Okamura, S. and Ichinokawa, M.
    • Journal Title

      Ecosphere

      Volume: 8 Pages: 1-9

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multi-subgroup gene screening using semi-parametric hierarchical2017

    • Author(s)
      Matsui S, Noma H, Qu P, Yoshio Sakai, Matsui K, Heuck C, Crowley J.
    • Journal Title

      Biometrics

      Volume: -

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Personalized dynamic prediction of death according to tumour progression2017

    • Author(s)
      Emura T, Nakatochi M, Matsui S, Michimae H, Rondeau V.
    • Journal Title

      Statistical Methods in Medical Research

      Volume: In press Issue: 9 Pages: 2842-2858

    • DOI

      10.1177/0962280216688032

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Confounding effects of microbiome on the susceptibility of2017

    • Author(s)
      Nakagome S, Chinen H, Iraha A, Hokama A, Takeyama Y, Sakisaka S,
    • Journal Title

      Human Genetics

      Volume: in press

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extreme sizes in the Gibbs-type exchangeable random2017

    • Author(s)
      Mano, S.
    • Journal Title

      Annals of Institute of Statistical Mathematics

      Volume: 69 Pages: 1-37

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An asymmetric logistic regression model for ecological data2016

    • Author(s)
      Komori, O., Eguchi, S., Ikeda, S., Okamura, H., Ichinokawa, M. and Nakayama, S.
    • Journal Title

      Methods in Ecology and Evolution

      Volume: 7(2) Issue: 2 Pages: 249-260

    • DOI

      10.1111/2041-210x.12473

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reproducible detection of disease-associated markers from gene expression data2016

    • Author(s)
      K. Omae, O. Komori and S.Eguchi
    • Journal Title

      BMC Medical Genomics

      Volume: 9(53) Issue: 1 Pages: 53-53

    • DOI

      10.1186/s12920-016-0214-5

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Robust Clustering Method in the Presence of Scattered Observations.2016

    • Author(s)
      A. Notsu and S. Eguchi.
    • Journal Title

      Neural Computation,

      Volume: In press Issue: 6 Pages: 1141-1162

    • DOI

      10.1162/neco_a_00833

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] CAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracy.2016

    • Author(s)
      Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T,
    • Journal Title

      Intensive Care Med.

      Volume: 42 Issue: 12 Pages: 2106-2107

    • DOI

      10.1007/s00134-016-4492-3

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Clinical and microarray analysis of breast cancers of all subtypes from two prospective preoperative chemotherapy studies.2016

    • Author(s)
      Okuma, H., Koizumi, F., Hirakawa, A., Nakatochi, M., Komori, O., Hashimoto,J., Kodaira, M., Yunokawa, M., Yamamoto, H.,Yonemori, K., Shimizu, C.,Fujiwara, Y. and Tamura, K.
    • Journal Title

      British Journal of Cancer

      Volume: 115 Issue: 4 Pages: 411-419

    • DOI

      10.1038/bjc.2016.184

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide DNA copy-number analysis in ACTS-CC trial of adjuvant chemotherapy for stage III colonic cancer.2016

    • Author(s)
      Ishikawa T, Uetake H, Murotani K, Kobunai T, Ishiguro M, Matsui S, Sugihara K.
    • Journal Title

      Anticancer Res.

      Volume: 36 Issue: 7 Pages: 853-860

    • DOI

      10.1038/bjc.2012.86

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A note on the Mantel-Haenszel estimators when the common effect assumptions are violated.2016

    • Author(s)
      Noma, H. and Nagashima, K.
    • Journal Title

      Epidemiologic Methods

      Volume: Accepted Issue: 1 Pages: 19-35

    • DOI

      10.1515/em-2015-0004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Risk assessment of radioisotope contamination for aquatic living resources in and around Japan.2015

    • Author(s)
      H. Okamura, S. Ikeda, T. Morita and S. Eguchi.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 113(14) Issue: 14 Pages: 3838-3843

    • DOI

      10.1073/pnas.1519792113

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Robust estimation of location and concentration parameters for the von Mises-Fisher distribution2015

    • Author(s)
      S. Kato, S. Eguchi
    • Journal Title

      Statistical Papers

      Volume: In press Issue: 1 Pages: 205-234

    • DOI

      10.1007/s00362-014-0648-9

    • Related Report
      2016 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Binary classification with pseudo exponential model and its application for multi task learning.2015

    • Author(s)
      T. Takenouchi, O. Komori and S. Eguchi.
    • Journal Title

      Entropy

      Volume: 17, 8 Pages: 5673-5694

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Generalized t-statistics for two-group classification.2015

    • Author(s)
      O. Komori, S. Eguchi and J. Copas.
    • Journal Title

      Biometrics

      Volume: 71, 2 Issue: 2 Pages: 404-416

    • DOI

      10.1111/biom.12265

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Extreme sizes in Gibbs-type exchangeable random partitions2015

    • Author(s)
      Shuhei Mano
    • Journal Title

      Annals of the Institute of Statistical Mathematics

      Volume: first online Issue: 1 Pages: 1-37

    • DOI

      10.1007/s10463-015-0530-0

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Analysis of case-cohort designs with binary outcomes: Improving efficiency using whole-cohort auxiliary information.2015

    • Author(s)
      Noma, H. and Tanaka, S.
    • Journal Title

      Statistical Methods in Medical Research

      Volume: to appear Issue: 2 Pages: 691-706

    • DOI

      10.1177/0962280214556175

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Individualized prostate-specific antigen threshold values to avoid overdiagnosis of prostate cancer and reduce unnecessary biopsy in elderly men2014

    • Author(s)
      Kanao K., Komori O., Nakashima J., Ohigashi T., Kikuchi E., Miyajima A., Nakagawa K., Eguchi S. and Oya M
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 44 Issue: 9 Pages: 852-859

    • DOI

      10.1093/jjco/hyu133

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Duality of Maximum Entropy and Minimum Divergence2014

    • Author(s)
      Shinto Eguchi, Osamu Komori and Atsumi Ohara
    • Journal Title

      Entropy

      Volume: 16 Issue: 7 Pages: 3552-3572

    • DOI

      10.3390/e16073552

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of statistical analysis plans in randomize-all phase III trials with a predictive biomarker2014

    • Author(s)
      Matsui S, Choai Y, Nonaka T
    • Journal Title

      Clinical Cancer Research

      Volume: 20 Issue: 11 Pages: 2820-2830

    • DOI

      10.1158/1078-0432.ccr-13-2698

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Response to letter to the editor by Dr Wages et al2014

    • Author(s)
      Hirakawa A, Matsui S
    • Journal Title

      Stat Med

      Volume: 33 Issue: 12 Pages: 2159-2160

    • DOI

      10.1002/sim.5972

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Bayesian hierarchical method to account for random effects in cytogenetic dosimetry based on calibration curves.2014

    • Author(s)
      Mano S, Suto Y.
    • Journal Title

      Radiation and Environmental Biophysics

      Volume: 53 Issue: 4 Pages: 775-780

    • DOI

      10.1007/s00411-014-0563-4

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The interaction of a single-nucleotide polymorphism with age on response to interferon-α and ribavirin therapy in female patients with hepatitis C infection.2014

    • Author(s)
      Nishino J, Sugiyama M, Nishida N, Tokunaga K, Mizokami M, Mano S
    • Journal Title

      J Med Virol

      Volume: 86(7) Issue: 7 Pages: 1130-3

    • DOI

      10.1002/jmv.23939

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of detection method for novel fusion gene using GeneChip exon array2014

    • Author(s)
      Wada, Y., Matsuura, M., Sugawara, M., Ushijima, M., Miyata, S., Nagasaki, K., Noda, T. and Miki, Y.
    • Journal Title

      Journal of Clinical Bioinformatics

      Volume: 4 Issue: 1 Pages: 3-3

    • DOI

      10.1186/2043-9113-4-3

    • URL

      https://pure.teikyo.jp/en/publications/81f3fe92-f20f-458c-9ad0-dac0394d9716

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ2014

    • Author(s)
      Osako T, Iwase T, Ushijima M, Horii R, Fukami Y, Kimura K, Matsuura M, Akiyama F
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 5 Pages: 576-582

    • DOI

      10.1111/cas.12381

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spontaneous clustering via minimum gamma-divergence2014

    • Author(s)
      Notsu A, Komori O, Eguchi S
    • Journal Title

      Neural Computation

      Volume: 26 Issue: 2 Pages: 421-448

    • DOI

      10.1162/neco_a_00547

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distinct cancer-specific survival in metastatic prostate cancer patients classified by a panel of single nucleotide polymorphisms of cancer-associated genes.2013

    • Author(s)
      Tsuchiya N, Matsui S, Narita S, Kamba T, Mitsuzuka K, Hatakeyama S, Horikawa Y, Inoue T, Saito S, Ohyama C, Arai Y, Ogawa O, Habuchi T.
    • Journal Title

      Genes Cancer.

      Volume: 4 Issue: 1-2 Pages: 54-60

    • DOI

      10.1177/1947601913481354

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking history.2013

    • Author(s)
      Aida J, Yokoyama A, Shimomura N, Nakamura K, Ishikawa N, Terai M, Poon S, Matsuura M, Fujiwara M, Sawabe M, Arai T, Takubo K
    • Journal Title

      PloS one

      Volume: 8 Issue: 5 Pages: 1-7

    • DOI

      10.1371/journal.pone.0063860

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Empirical Bayes ranking and selection methods via semiparametric hierarchical mixture models in microarray studies2013

    • Author(s)
      Noma H, Matsui S
    • Journal Title

      Statistics in Medicine

      Volume: 32 Issue: 11 Pages: 1904-1916

    • DOI

      10.1002/sim.5718

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ポストゲノム時代に遺伝疫学を考える (総説)2013

    • Author(s)
      間野修平
    • Journal Title

      生物の科学 遺伝

      Volume: 67 Pages: 368-371

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Nested case control study of proteomic biomarkers for interstitial lung disease in Japanese patients with non-small-cell lung cancer treated with erlotinib: a multicenter phase IV study (JO21661)2013

    • Author(s)
      Atagi S, Katakami N, Yoshioka H, Fukuoka M, Kudoh S, Ogiwara A, Imai M, Ueda M, Matsui S
    • Journal Title

      Clinical Lung Cancer

      Volume: 14 Issue: 4 Pages: 407-417

    • DOI

      10.1016/j.cllc.2012.12.006

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Robust independent component analysis via minimum gamma-divergence estimation2013

    • Author(s)
      Chen PW, Hung H, Komori O, Huang SY, Eguchi S
    • Journal Title

      IEEE Journal of Selected Topics in Signal Processing

      Volume: 7 Issue: 4 Pages: 614-624

    • DOI

      10.1109/jstsp.2013.2247024

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Geometry on positive definite matrices induced from V-potential function2013

    • Author(s)
      Ohara, A. and Eguchi, S.
    • Journal Title

      Geometric Science of Information. Lecture Notes in Computer Science

      Volume: 8085 Pages: 621-629

    • DOI

      10.1007/978-3-642-40020-9_69

    • ISBN
      9783642400193, 9783642400209
    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Group Invariance of Information Geometry on q-Gaussian Distributions Induced by Beta-Divergence2013

    • Author(s)
      Atsumi Ohara and Shinto Eguchi
    • Journal Title

      Entrtopy

      Volume: 15 Issue: 11 Pages: 4732-4747

    • DOI

      10.3390/e15114732

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The number of candidate variants in exome sequencing for Mendelian disease under no genetic heterogeneity2013

    • Author(s)
      Nishino, J. and Mano, S.
    • Journal Title

      Computational and Mathematical Methods in Medicine

      Volume: 2013 Pages: 1-13

    • DOI

      10.1155/2013/179761

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Editorial note on special issue "Statistical Analysis of Biomarkers for Personalized Medicine," by Computational and Mathematical Methods in Medicine2013

    • Author(s)
      Eguchi S. Matsui S, Huang SY, Hsiao CK
    • Journal Title

      (総説・会議録)

      Volume: - Pages: 2-2

    • DOI

      10.1155/2013/467420

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An efficient semiparametric empirical Bayes method for the optimal discovery procedure in multiple significance testing2013

    • Author(s)
      Noma, H. and Matsui, S.
    • Journal Title

      Computational and Mathematical Methods in Medicine 2013

      Volume: (Article ID 568480) Pages: 568480-568480

    • DOI

      10.1155/2013/568480

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer outlier analysis based on mixture modeling of gene expression data2013

    • Author(s)
      Mori, K., Oura, T., Noma, H. and Matsui, S.
    • Journal Title

      Computational and Mathematical Methods in Medicine

      Volume: 2013 Pages: 1-8

    • DOI

      10.1155/2013/693901

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of heterogeneous structures on the Gaussian copula model using predictive power entropy2013

    • Author(s)
      Notsu, A., Kawasaki, Y. and Eguchi, S.
    • Journal Title

      ISRN Probability and Statistics

      Volume: 2013 Pages: 1-10

    • DOI

      10.1155/2013/787141

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple suboptimal solutions for prediction rules in gene expression data2013

    • Author(s)
      Komori, O., Pritchard, M. and Eguchi, S.
    • Journal Title

      Computational and Mathematical Methods in Medicine

      Volume: 2013 Pages: 1-14

    • DOI

      10.1155/2013/798189

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genomic biomarkers for personalized medicine: development and validation in clinical studies2013

    • Author(s)
      Matsui, S.
    • Journal Title

      Computational and Mathematical Methods in Medicine

      Volume: 2013 Pages: 1-9

    • DOI

      10.1155/2013/865980

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Multiple Testing Based on Semi-Parametric Hierarchical Mixture Models underDependency in Disease-Association Studies with Neuroimaging Data2018

    • Author(s)
      Ryo Emoto, Atsushi Kawaguchi, Hisako Yoshida, Shigeyuki Matsui
    • Organizer
      Eastern North American Region International Biometric Society, 2018 Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 先端医学研究の発展を担うデータサイエンス2018

    • Author(s)
      野間久史
    • Organizer
      第12回日本統計学会春季集会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Robustified asymmetric logistic regression model for global fish stock assessment2017

    • Author(s)
      Komori, O., Eguchi, S., Hiroshi, O., Ichinokawa, M.
    • Organizer
      CFAS 2017:International Conference on Fisheries and Aquatic Sciences
    • Place of Presentation
      Patong Beach Hotel, Thailand
    • Year and Date
      2017-03-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Two paradigms in statistical prediction2017

    • Author(s)
      S.Euchi
    • Organizer
      The International Conference on Bioinformatics and Biostatistics for Agriculture Health and Environment
    • Place of Presentation
      University of Rajshahi in Bangladesh
    • Year and Date
      2017-01-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Asymmetric logistic regression model2017

    • Author(s)
      Komori, O.
    • Organizer
      The International Conference on Bioinformatics and Biostatistics for Agriculture Health and Environment,
    • Place of Presentation
      University of Rajshahi in Bangladesh
    • Year and Date
      2017-01-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Information Geometry of Predictor Functions in a Regression Model2017

    • Author(s)
      Shinto Eguchi, Katsuhiro Omae
    • Organizer
      3rd conference on Geometric Science of Information
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 一般化ガンマクラスタリングについて2017

    • Author(s)
      野津昭文,大前勝弘,江口真透
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 一般化平均を用いたコックス比例ハザードモデルの拡張2017

    • Author(s)
      大前勝弘,江口真透
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 回帰モデルの予測関数の情報幾何2017

    • Author(s)
      江口真透,大前勝弘
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生態デ-タのためポアソン点過程-準線形モデリング-2017

    • Author(s)
      小森理,三枝祐輔,江口真透
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 擬似線形関数に基づくクラスタ毎の異質性を考慮した回帰モデル2017

    • Author(s)
      林賢一,江口真透
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 一般化平均によるモデルと推定2017

    • Author(s)
      江口真透
    • Organizer
      科研費シンポジュウム「統計学, 機械学習の数理とその応用」
    • Related Report
      2017 Annual Research Report
  • [Presentation] Precision Medicineとビッグデータ,統計科学2017

    • Author(s)
      野間久史
    • Organizer
      第56回大分統計談話会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 個別治療効果推定に対する機械学習的アプローチ2017

    • Author(s)
      菅澤翔之助,野間久史
    • Organizer
      日本計算機統計学会第31回大会シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生態デ-タのためのポアソン点過程モデル?準線形モデリング?2017

    • Author(s)
      小森理
    • Organizer
      統計関連学会連合大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The optimal discovery procedure: A generalization of the Neyman-Pearson fundamental lemma to multiple significance testing.2016

    • Author(s)
      野間久史
    • Organizer
      統計談話会第54回大会
    • Place of Presentation
      富士通大分システムラボラトリ
    • Year and Date
      2016-10-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] 分布の異質性を考慮した判別手法2016

    • Author(s)
      小森理
    • Organizer
      統計関連学会連合大会
    • Place of Presentation
      金沢大学
    • Year and Date
      2016-09-04
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cancer outlier analysis based on a nested2016

    • Author(s)
      Oura T, Matsui K, Matsui S.
    • Organizer
      XXVIIIth International Biometric Conference
    • Place of Presentation
      Victoria Convention Centre, Victoria, Canada
    • Year and Date
      2016-07-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Information Geometry associated with two generalized means2016

    • Author(s)
      S.Euchi
    • Organizer
      Information Geometry and its applications IV
    • Place of Presentation
      Liblice, Czech Republic
    • Year and Date
      2016-06-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A simple mixture model for probability density estimation based on a quasi divergence (poster)2016

    • Author(s)
      Komori, O. and Eguchi, S
    • Organizer
      Information Geometry and its applications IV
    • Place of Presentation
      Liblice, Czech Republic
    • Year and Date
      2016-06-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Information geometry associated with two generalized means2016

    • Author(s)
      Eguchi, S., Komori, O. and Ohara, A.
    • Organizer
      Information Geometry and its applications IV
    • Place of Presentation
      Liblice, Czech Republic
    • Year and Date
      2016-06-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A comparison of multiple testing methods for effective strategies in genome-wide association studies.2016

    • Author(s)
      大谷隆浩,野間久史,西野穣,松井孝太,松井茂之.
    • Organizer
      2016年度日本計量生物学会年会
    • Place of Presentation
      統計数理研究所,東京
    • Year and Date
      2016-03-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Asymptotic behaviors of the Mantel-Haenszel estimators and their robust variance estimators when the common effect assumptions are violated.2016

    • Author(s)
      Noma, H., Nagashima, K.
    • Organizer
      Eastern North American Region International Biometric Society 2016 Spring Meeting,
    • Place of Presentation
      JW Marriott Austin, Austin, Texas, US
    • Year and Date
      2016-03-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Estimating the structure of big data: new approach to screening and classification in genomic studies.2016

    • Author(s)
      Matsui S.
    • Organizer
      CREST International Symposium on Big Data Application
    • Place of Presentation
      Japan Science and Technology Agency, Tokyo, Japan
    • Year and Date
      2016-03-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A classification method based on nested normal mixture models with cancer outlier profiles.2015

    • Author(s)
      Matsui K, Oura T, Matsui S.
    • Organizer
      East Asia Regional Biometric Conference
    • Place of Presentation
      Kyushu University, Fukuoka, Japan
    • Year and Date
      2015-12-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Re-evaluation of the multiple testing strategy for detecting disease-related genetic variants in genome-wide association studies.2015

    • Author(s)
      Otani, T., Noma, H., Nishino, J., Matsui, S.
    • Organizer
      East Asia Regional Biometric Conference 2015
    • Place of Presentation
      Kyushu University, Fukuoka, Japan
    • Year and Date
      2015-12-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Spontaneous learning for clustered data via gamma power divergence.2015

    • Author(s)
      Eguchi S.
    • Organizer
      The 9th Conference of the Asian Regional Section of the IASC
    • Place of Presentation
      National University of Singapore, Singapore.
    • Year and Date
      2015-12-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Extension of AUC for classification considering heterogeneity in distributions.2015

    • Author(s)
      Komori, O. and Eguchi, S.
    • Organizer
      The 9th Conference of the Asian Regional Section of the IASC-ARS 2015
    • Place of Presentation
      National University of Singapore, Singapore.
    • Year and Date
      2015-12-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Information geometry and spontaneous data learning.2015

    • Author(s)
      Eguchi S.
    • Organizer
      2015 Workshop on High-Dimensional Statistical Analysis
    • Place of Presentation
      Academia Sinica, Taiwan
    • Year and Date
      2015-12-11
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Generalized t-statistic and AUC for binary classification.2015

    • Author(s)
      Komori, O. and Eguchi, S.
    • Organizer
      Workshop on High-Dimensional Statistical Analysis
    • Place of Presentation
      Academia Sinica, Taiwan
    • Year and Date
      2015-12-11
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Hierarchical mixture modelling and empirical Bayes estimationin biomedical studies with high-dimensional data.2015

    • Author(s)
      Matsui S.
    • Organizer
      Frontiers inData-Driven Science and Technology: Recent Advances in Machine Learningand Applications.
    • Place of Presentation
      Nagoya Institute of Technology, Nagoya, Japan
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Spontaneous learning for data distributions via minimum divergence.2015

    • Author(s)
      Eguchi S.
    • Organizer
      ICMS Workshop on Computational information geometry for image and signal processing
    • Place of Presentation
      Edinburgh.
    • Year and Date
      2015-09-21
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ゲノムワイド関連解析データを用いた複雑疾患の階層混合モデル解析2015

    • Author(s)
      西野穣, 高地雄太, 野間久史, 重水大智, 森園隆, 角田達彦, 松井茂之.
    • Organizer
      2015年度統計関連学会連合大会
    • Place of Presentation
      岡山大学
    • Year and Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 異質性が内在する2標本検定問題におけるロバストな統計量2015

    • Author(s)
      大前勝弘,小森理,江口真透
    • Organizer
      統計関連学会連合大会2015
    • Place of Presentation
      岡山大学 津島キャンパス
    • Year and Date
      2015-09-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 自発的なデータ学習について2015

    • Author(s)
      江口 真透
    • Organizer
      統計関連学会連合大会2015
    • Place of Presentation
      岡山大学 津島キャンパス
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] 分布の異質性を考慮したt統計量とAUCの一般化2015

    • Author(s)
      小森理,江口真透
    • Organizer
      統計関連学会連合大会2015
    • Place of Presentation
      岡山大学 津島キャンパス
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] クラスタリングのためのロバストなK-平均法について2015

    • Author(s)
      野津昭文,江口真透
    • Organizer
      統計関連学会連合大会2015
    • Place of Presentation
      岡山大学 津島キャンパス
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] Efficient study designs and semiparametric inference methods for developing genomic biomarkers in cancer clinical research.2015

    • Author(s)
      Noma, H.
    • Organizer
      Pacific Rim Cancer Biostatistics Conference
    • Place of Presentation
      Washington Athletic Club, Seattle, US,
    • Year and Date
      2015-08-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Efficient study designs for developing genomic biomarkers and semiparametric inference.2015

    • Author(s)
      Noma, H.
    • Organizer
      Joint Statistical Meeting 2015
    • Place of Presentation
      Washington State Convention Center, Seattle, US
    • Year and Date
      2015-08-10
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 自発的なデータ学習の展望2015

    • Author(s)
      江口 真透
    • Organizer
      平成27年度 統計科学セミナー
    • Place of Presentation
      九州大学伊都キャンパス
    • Year and Date
      2015-07-17
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 2群判別のための多重マーカーの一般化 t-統計量について:セミパラメトリックスとラッソ2015

    • Author(s)
      江口 真透、小森 理
    • Organizer
      バイオ統計学の挑戦と貢献
    • Place of Presentation
      福岡
    • Year and Date
      2015-02-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 疾患の分子診断法開発における効率的な臨床研究デザインとセミパラメトリック統計理論.2014

    • Author(s)
      野間久史
    • Organizer
      九州大学大学院数理学研究院統計科学セミナー
    • Place of Presentation
      九州大学,福岡
    • Year and Date
      2014-12-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Path connectivity on a space of probability density function space.2014

    • Author(s)
      Eguchi, S.
    • Organizer
      Taipei, Taiwan
    • Place of Presentation
      和光市
    • Year and Date
      2014-12-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] On the Mantel-Haenszel estimators when the common effect assumptions are violated.2014

    • Author(s)
      Noma, H. and Nagashima, K.
    • Organizer
      Kyoto International Conference on Modern Statistics in the 21st Century
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2014-11-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Duality in a maximum generalized entropy model.2014

    • Author(s)
      Eguchi S., Komori, O. Ohara, A.
    • Organizer
      34th International Workshop on Bayesian Inference and Maximum Entropy Methods in Science and Engineering
    • Place of Presentation
      Amboise France
    • Year and Date
      2014-09-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] Maximum power entropy method for ecological data analysis.2014

    • Author(s)
      Komori, O., Eguchi, S.
    • Organizer
      34th International Workshop on Bayesian Inference and Maximum Entropy Methods in Science and Engineering.
    • Place of Presentation
      Amboise France
    • Year and Date
      2014-09-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] A novel boosting algorithm for multi-task learning based on the Itakuda-Saito divergence.2014

    • Author(s)
      Takenouchi T. Komori O, Eguchi S.
    • Organizer
      34th International Workshop on Bayesian Inference and Maximum Entropy Methods in Science and Engineering
    • Place of Presentation
      Amboise France
    • Year and Date
      2014-09-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] 統計学から学んだ三つのレッスン2014

    • Author(s)
      江口 真透
    • Organizer
      統計関連学会連合大会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Multiple Imputation法による2段階ケースコントロール研究の解析2014

    • Author(s)
      野間久史
    • Organizer
      2014年度統計関連学会連合大会
    • Place of Presentation
      東京大学,東京
    • Year and Date
      2014-09-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] マイクロアレイデータによるロバストな遺伝子ランキングを用いた表現型予測2014

    • Author(s)
      大前 勝弘、小森 理、江口 真透
    • Organizer
      統計関連学会連合大会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Multiple Imputation法によるネステッドケースコントロール研究.ケースコホート研究の解析2014

    • Author(s)
      野間久史
    • Organizer
      2014年度統計関連学会連合大会
    • Place of Presentation
      東京大学,東京
    • Year and Date
      2014-09-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Statistical analysis plans in phase III all-comers clinical trials with a predictive biomarker.2014

    • Author(s)
      Matsui S.
    • Organizer
      The XXVII International Biometric Conference.
    • Place of Presentation
      Florence
    • Year and Date
      2014-07-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Robust ranking method via repeated random partition for gene expressions data.2014

    • Author(s)
      Omae, K., Komori, O., Eguchi, S.
    • Organizer
      The 3rd Institute of Mathematical Statistics Asia Pacific Rim Meeting
    • Place of Presentation
      Taipei Taiwan
    • Year and Date
      2014-06-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Generalized entropy and divergence in statistical learning.2014

    • Author(s)
      Eguchi, S., Komori, O.
    • Organizer
      The 3rd Institute of Mathematical Statistics Asia Pacific Rim Meeting
    • Place of Presentation
      Taipei Taiwan
    • Year and Date
      2014-06-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Possible generalization of MAXENT2014

    • Author(s)
      Eguchi, S.
    • Organizer
      International symposium on innovation and challenges for fisheries assessment and management
    • Place of Presentation
      慶應義塾大学理工学部 矢上キャンパス,神奈川県
    • Related Report
      2013 Annual Research Report
  • [Presentation] A class of u-statistics combining multiple markers for two-group classification2013

    • Author(s)
      Komori, O., Hung, H., Chen, P., Huang, Su-Yun and Eguchi, S.
    • Organizer
      Joint Meeting of the IASC Satellite Conference for the 59th ISI WSC and the 8th Conference of the Asian Regional Section of the IASC
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] 海洋生態系を測るための関数データ解析2013

    • Author(s)
      江口真透
    • Organizer
      統計関連学会連合大会
    • Place of Presentation
      大阪大学,大阪府
    • Related Report
      2013 Annual Research Report
  • [Presentation] The optimal discovery procedure in multiple significance testing: An empirical Bayes method based on semiparametric hierarchical mixture models2013

    • Author(s)
      野間久史, 松井茂之
    • Organizer
      統計関連学会連合大会
    • Place of Presentation
      大阪大学,大阪府
    • Related Report
      2013 Annual Research Report
  • [Presentation] Ancestral Processes with Collision and Bias2013

    • Author(s)
      Mano, S.
    • Organizer
      Workshop on Coalescent Theory: New Developments and Applications
    • Place of Presentation
      Centre de Researches Mathematiques, Universite de Montreal, Montreal, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] 2値判別分析におけるモデルと推定の関係について2013

    • Author(s)
      江口真透
    • Organizer
      科学研究費シンポジウム「一般化線形モデルの最新の展開とその周辺」
    • Place of Presentation
      千葉大学理学部,千葉県
    • Related Report
      2013 Annual Research Report
  • [Presentation] 情報幾何の展開―アダブーストからポアンカレ予想まで2013

    • Author(s)
      江口真透
    • Organizer
      特別講演会
    • Place of Presentation
      千葉大学理学部,千葉県
    • Related Report
      2013 Annual Research Report
  • [Presentation] Pattern Recognition for Marine Ecological Assessments2013

    • Author(s)
      Eguchi, S.
    • Organizer
      The Ninth ICSA International Conference: Challenges of Statistical Methods for Interdisciplinary Research and Big Data
    • Place of Presentation
      Hong Kong Baptist University, China
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] Computational Information Geometry2017

    • Author(s)
      Eguchi, S., A. Notsu, O. Komori
    • Total Pages
      21
    • Publisher
      Springer International Publishing
    • ISBN
      9783319470580
    • Related Report
      2017 Annual Research Report
  • [Book] International Conference on Geometric Science of Information,2017

    • Author(s)
      Shinto Eguchi, Katsuhiro Omae
    • Total Pages
      8
    • Publisher
      Springer, Cham
    • Related Report
      2017 Annual Research Report
  • [Book] Spontaneous Learning for Data Distributions via Minimum Divergence2017

    • Author(s)
      Eguchi, S., A. Notsu, O. Komori
    • Total Pages
      299
    • Publisher
      Springer International Publishing
    • Related Report
      2016 Annual Research Report
  • [Book] Spontaneous learning for data distributions via minimum divergence. In Computational Information Geometry in Signal and Image Processing,2016

    • Author(s)
      S. Eguchi, A. Notsu and O. Komori
    • Publisher
      Springer
    • Related Report
      2015 Annual Research Report
  • [Book] Statistical and machine-learning methods for class prediction in high dimension. Design and Analysis of Clinical Trials for Predictive Medicine.2015

    • Author(s)
      O.Komori and S.Eguchi.
    • Total Pages
      400
    • Publisher
      Chapman Hall/CRC
    • Related Report
      2015 Annual Research Report
  • [Book] Path Connectedness on a Space of Probability Density Functions. In Geometric Science of Information 20152015

    • Author(s)
      Eguchi, S.and Komori, O.
    • Total Pages
      790
    • Publisher
      Springer International Publishing.
    • Related Report
      2015 Annual Research Report
  • [Book] 抗がん剤副作用予測システム.血液内科2015

    • Author(s)
      松浦正明,牛嶋 大
    • Total Pages
      545
    • Publisher
      科学評論社
    • Related Report
      2015 Annual Research Report
  • [Book] Statistical issues in clinical development and validation of genomic signatures. In Design and Analysis of Clinical Trials for Predictive Medicine.2015

    • Author(s)
      Matsui S.
    • Total Pages
      400
    • Publisher
      CRC Press
    • Related Report
      2015 Annual Research Report
  • [Book] Univariate analysis for gene screening: beyond the multiple testing. In Design and Analysis of Clinical Trials for Predictive Medicine.2015

    • Author(s)
      Noma H, Matsui S.
    • Total Pages
      400
    • Publisher
      CRC Press
    • Related Report
      2015 Annual Research Report
  • [Book] Development and validation of continuous genomic signatures in randomized clinical trials. In Design and Analysis of Clinical Trials for Predictive Medicine.2015

    • Author(s)
      Matsui S.
    • Total Pages
      400
    • Publisher
      CRC Press
    • Related Report
      2015 Annual Research Report
  • [Book] Design and Analysis of Clinical Trials for Predictive Medicine.2015

    • Author(s)
      Osamu Komori and Shinto Eguchi
    • Total Pages
      400
    • Publisher
      Chapman & Hall/CRC
    • Related Report
      2014 Annual Research Report
  • [Book] Design and Analysis of Clinical Trials for Predictive Medicine2015

    • Author(s)
      Noma, H. and Matsui, S.
    • Total Pages
      400
    • Publisher
      Chapman & Hall/CRC
    • Related Report
      2014 Annual Research Report
  • [Book] Bayesian Inference and Maximum Eentropy Methods in Science and Engineering (MAXENT 2014)2014

    • Author(s)
      T Takenouchi, O Komori, S Eguchi.
    • Total Pages
      621
    • Publisher
      AIP Publishing
    • Related Report
      2014 Annual Research Report
  • [Book] Bayesian Inference and Maximum Eentropy Methods in Science and Engineering (MAXENT 2014)2014

    • Author(s)
      S Eguchi, O Komori, A Ohara.
    • Total Pages
      621
    • Publisher
      AIP Publishing
    • Related Report
      2014 Annual Research Report
  • [Book] Developments in Statistical Evaluation of Clinical Trials2014

    • Author(s)
      Matsui S, Nonaka T, Choai Y.
    • Total Pages
      361
    • Publisher
      Springer
    • Related Report
      2014 Annual Research Report
  • [Book] Developments in Statistical Evaluation of Clinical Trials2014

    • Author(s)
      Hirakawa A, Matsui S.
    • Total Pages
      361
    • Publisher
      Springer
    • Related Report
      2014 Annual Research Report
  • [Book] Gene screening in the development of genomic signatures. in Design and Analysis of Clinical Trials for Predictive Medicine2014

    • Author(s)
      Noma, H. and Matsui, S. (Matsui, S., Buyse, M. and Simon, R. (eds.), Boca Raton)
    • Total Pages
      425
    • Publisher
      Chapman and Hall/CRC
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2022-12-27  

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