| Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Outline of Final Research Achievements |
This study proposes a novel approach for the early detection of cognitive impairment in the elderly, in which we focused on the prosodic features of speech sound during the subject’s answers to the questionnaire; the first was to detect signal and prosodic signs of cognitive impairment, the second was to take a measurement of cerebral blood flow (CBF). We then have developed a prototype of prosody-CBF hybrid screening system and discussed the cost-effectiveness and the discrimination performance. Moreover, MCI group is divided into two subtypes of Nonamnestic-MCI (N-MCI) composed of ten participants and Amnestic-MCI (A-MCI) composed of nine participants. We will present a comparative analysis of CBF activation between CN, N-MCI, A-MCI, and AD, by statistical tests of between-group significant differences using fNIRS signals of oxy-Hb during the cognitive task.
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