Searching and risk assessment for indoor persistent chemicals -Use of companion animals as the indicators-
| Project/Area Number |
25281050
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental risk control and evaluation
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| Research Institution | Ehime University (2014-2015)
Tottori University (2013) |
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Principal Investigator |
KUNISUE TATSUYA 愛媛大学, 沿岸環境科学研究センター, 教授 (90380287)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO YOSHIHARU 鳥取大学, 農学部, 教授 (50194410)
SUZUKI GO 国立研究開発法人国立環境研究所, 資源循環・廃棄物研究センター, 研究員 (70414373)
HORAI SAWAKO 鳥取大学, 地域学部, 准教授 (60512689)
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| Co-Investigator(Renkei-kenkyūsha) |
ISOBE TOMOHIKO 国立研究開発法人国立環境研究所, 環境健康研究センター, 主任研究員 (50391066)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2015: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2013: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | 残留性有機汚染物質 / コンパニオンアニマル / ハウスダスト / バイオアッセイ / リスク評価 / レアメタル |
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| Outline of Final Research Achievements |
Contamination status, exposure pathways, and risk assessment of persistent organic pollutants (POPs) such as polybrominated diphenyl ethers (PBDEs), personal care products (PCPs), and rare metals were studied for companion animals, pet dogs and cats, which could be useful “sentinel animals” to evaluate indoor exposure of the above chemicals for infants. The study results revealed that companion animals are exposed to POPs, PCPs, and trace elements via not only their foods but also indoor dust, and indicated that PBDE exposure might adversely affect thyroid hormone homeostasis in pet cats. The present study provided valuable scientific findings to assess the indoor environment-derived risks for companion animals, and infants investigating in the Japan Environment and Children’s Study (JECS).
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] Organohalogen compounds in pet dog and cat: Do pets biotransform natural brominated products in food to harmful hydroxlated substances?2016
Author(s)
Mizukawa H, Nomiyama K, Nakatsu S, Iwata H, Yoo J, Kubota A, Yamamoto M, Ishizuka M, Ikenaka Y, Nakayama M.M.S, Kunisue T, Tanabe S
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Journal Title
Environmental Science & Technology
Volume: 50
Issue: 1
Pages: 444-452
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Effect-based approach for hazard identification of house dust: Case studies by using in vitro bioassays detecting dioxin-like compounds, thyroid and reproductive toxicants.2014
Author(s)
Suzuki, G., Tue, N.M., Takahashi, S., Tanabe, S., Sakai, S., Takigami, H.
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Journal Title
Current Organic Chemistry
Volume: 18
Issue: 17
Pages: 2231-2239
DOI
Related Report
Peer Reviewed
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[Presentation] Contamination status of organohalogen compounds and their hydroxylated metabolites in pet cats: Effects on thyroid hormones homeostasis2015
Author(s)
Yamamoto, Y., Nomiyama, K., Mizukawa, H., Takiguchi, M., Ishizuka, M., Kunisue, T. and Tanabe, S.
Organizer
Society of Environmental Toxicology and Chemistry (SETAC) North America 36th Annual Meeting
Place of Presentation
Salt Lake City, Utah, USA
Year and Date
2015-11-01
Related Report
Int'l Joint Research
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