| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Outline of Final Research Achievements |
For the purpose of development of novel biotechnology that can be applied in low carbon society “methanol economy”, we have studied molecular basis of metabolic physiology of C1-microorganisms that can utilize C1 compounds, such as methane and methanol, and its application. We focused on two major useful traits of methylotrophic yeasts, “strong methanol-inducible gene expression” and “ability to proliferate at the phyllosphere”. For example, molecular function of the transcriptional factor complex responsible for methanol-inducible gene expression was elucidated. Furthermore, we revealed nitrogen utilization and its regulation of the methylotrophic yeast at the phyllosphere.
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