Mechanical circulatory support system development platform for congenital heart diseases using a small implantable actuator

• Project/Area Number: 25282126
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Tohoku University
• Principal Investigator: Shiraishi Yasuyuki 東北大学, 加齢医学研究所, 准教授 (00329137)
• Co-Investigator(Kenkyū-buntansha): MIURA HIDEKAZU 東北大学, 加齢医学研究所, 助教 (50451894) ; YAMBE TOMOYUKI 東北大学, 加齢医学研究所, 教授 (70241578) ; SASAKI KAZUMASU 東北大学, 加齢医学研究所, 助教 (80738948)
• Co-Investigator(Renkei-kenkyūsha): YAMAGISHI MASAAKI 京都府立医科大学, 小児心臓血管外科, 教授 (40182422) ; AKIYAMA MASATOSHI 東北大学, 心臓血管外科, 講師 (80526450) ; SAIKI YOSHIKATSU 東北大学, 心臓血管外科, 教授 (50372298)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000); Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2014: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2013: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
• Keywords: 先天性心疾患 / 人工心筋 / 形状記憶合金線維 / マイクロマシン / 循環器・高血圧

Outline of Final Research Achievements

Long-term mechanical support systems development resources are needed for the surgical treatment of congenital heart failure. We employed a small-sized nano-tech Ni-Ti shape memory alloy fibre as an implantable actuator for the mechanical circulatory support. We focused on the development of two types of implantable devices; a) a right ventricular external contraction support belt, and b) a Fontan circulation active support system that could be used with the total cavopulmonary connection. We examined the systems function in the originally designed mock circulatory system with a silicone-rubber right ventricular model as well as in the animal models. As a result of this study, it was indicated that the micro actuation system for congenital heart failure support could be useful to exhibit the hemodynamic effect for the totally implantable system design.

Research Products

• [Journal Article] Sensorless cardiac phase detection for synchronized control of ventricular assist devices using nonlinear kernel regression model (2016)
  • Author(s): Hirohashi Y, Tanaka A, Yoshizawa M, Sugita N, Abe M, Kato T, Shiraishi Y, Miura H, Yambe T
  • Journal Title: J Artif Organs Volume: 2016
  • Peer Reviewed
• [Journal Article] Development of a thermodynamic control system for the Fontan circulation pulsation device using shape memory alloy fibers (2015)
  • Author(s): Yamada A, Shiraishi Y, Miura H, Yamagishi M, Yambe T
  • Journal Title: J Artif Organs Volume: 印刷中 Issue: 3 Pages: 199-205
  • DOI: 10.1007/s10047-015-0827-z
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Initial Acute Animal Experiment Using a New Miniature Axial Flow Pump in Series With the Natural Heart (2015)
  • Author(s): E.Okamoto, T.Yano, Y.Shiraishi, H.Miura, T.Yambe, Y.Mitamura
  • Journal Title: Artificial Organs Volume: 39 Issue: 8 Pages: 701-704
  • DOI: 10.1111/aor.12558
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Fundamental Analysis and Development of the Current and Voltage Control Method by Changing the Driving Frequency for the Transcutaneous Energy Transmission System (2015)
  • Author(s): H. Miura, A. Yamada, Y. Shiraishi, T. Yambe
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2015 Pages: 1319-1322
  • DOI: 10.1109/embc.2015.7318611
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Mechanical circulatory assistance and a non invasive perfusion measurements (2015)
  • Author(s): Shiraishi Y, Sasaki K, Kaneko Y, Kitano T, Watanabe S, Inoue Y, Tsuboko Y, Yamada A, Miura H, Tanaka A, Yoshizawa M, Katahira S, Saiki Y, Homma D, Yambe T
  • Journal Title: Biomedical Science and Technology 2015 Volume: 2015 Pages: 3-5
• [Journal Article] Examination of the polymer coated shape memory alloy actuator for the implantable artificail mechanical organs (2015)
  • Author(s): Yamada A, Shiraishi Y, Miura H, Taira Y, Tsuboko Y, Inoue Y, Sasaki K, Homma D, Yambe T
  • Journal Title: Biomedical Science and Technology 2015 Volume: 2015 Pages: 15-17
• [Journal Article] Conceptual design of a new total cavopulmonary connection assitace device for Fontan circulation (2015)
  • Author(s): Ikeda J, Shiraishi Y, Tsuboko Y, Yamada A, Inoue Y, Taira Y, Suzuki T, Mura S, Homma D, Yamagishi M, Yambe T
  • Journal Title: Biomedical Science and Technology 2015 Volume: 2015 Pages: 42-45
• [Journal Article] 2. Numerical analysis of hemodynamic changes in the left atrium due to atrial fibrillation. (2014)
  • Author(s): Koizumi R, Funamoto K, Hayase T, Kanke Y, Shibata M, Shiraishi Y, Yambe T.
  • Journal Title: J Biomech. Volume: 48 Issue: 3 Pages: 472-478
  • DOI: 10.1016/j.jbiomech.2014.12.025
  • Peer Reviewed
• [Journal Article] Discrimination ability and reproducibility of a new index reflecting autonomic nervous function based on pulsatile amplitude of photoplethysmography (2014)
  • Author(s): Kano Y, Yoshizawa M, Sugita N, Abe M, Homma N, Tanaka A, Yamauchi T, Miura H, Shiraishi Y, Yambe T
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2014 Pages: 1794-1800
  • DOI: 10.1109/embc.2014.6943957
  • Peer Reviewed
• [Journal Article] Improvement of a Shape Memory Alloy Fibered Aortic Pulsation Device (2014)
  • Author(s): Hashem MO, Shiraishi Y, Yamada A, Yambe T, Homma D
  • Journal Title: IFMBE Proceedings Volume: 43 Pages: 399-402
  • DOI: 10.1007/978-3-319-02913-9_102
  • ISBN: 9783319029122, 9783319029139
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Design of a right ventricular simulator for the evaluation of artificial pulmonary valve (2013)
  • Author(s): Tsuboko Y, Matsuo S, Shiraishi Y, Yambe T, et al.
  • Journal Title: IFMBE Proc Volume: 43 Pages: 440-443
  • DOI: 10.1007/978-3-319-02913-9_112
  • ISBN: 9783319029122, 9783319029139
  • Peer Reviewed
• [Journal Article] Peristaltic Hemodynamics of a New Pediatric Circulatory Assist (2013)
  • Author(s): A. Yamada, Y. Shiraishi, H. Miura, T. Yambe, M. H. Omran, T. Shiga, Y. Tsuboko, D. Homma, M. Yamagishi
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2013 Pages: 683-686
  • DOI: 10.1109/embc.2013.6609592
  • Peer Reviewed
• [Journal Article] Hemodynamic Effects of Pressure-Volume Relation in the Atrial (2013)
  • Author(s): Takuya Shiga, Takehito Kuroda, Yusuke Tsuboko, Hidekazu Miura, Yasuyuki Shiraishi, and Tomoyuki Yambe
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2013 Pages: 1815-1818
  • DOI: 10.1109/embc.2013.6609875
  • Peer Reviewed
• [Journal Article] Interbeat control of a ventricular assist device for variable pump performance. (2013)
  • Author(s): Tanaka A, Moriya A, Yoshizawa M, Shiraishi Y, Yambe T.
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc. 2013;2013 Volume: 2013 Pages: 5735-5758
  • DOI: 10.1109/embc.2013.6610853
  • Peer Reviewed
• [Journal Article] Controlling methods of a newly developed extra aortic counter-pulsation device using shape memory alloy fibers (2013)
  • Author(s): Hashem MO, Yamada A, Tsuboko Y, Muira H, Homma D, Shiraishi Y, Yambe T
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2013 Pages: 2740-3
  • DOI: 10.1109/embc.2013.6610107
  • Peer Reviewed
• [Journal Article] Expansion capsules for diet control with artificial organ technology. (2013)
  • Author(s): Yambe T, Shiraishi Y, Miura H, Sugita N, Yoshizawa M.
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc. 2013;2013:5739-42. Volume: 2013 Pages: 5739-5742
  • DOI: 10.1109/embc.2013.6610854
  • Peer Reviewed
• [Journal Article] Frameworks in attachment of an artificial myocardium on chronic heart models using shape memory alloy fibers (2013)
  • Author(s): Shiraishi Y, Yambe T, Hayatsu Y, Akiyama M, Yamada A, Hashem M, Tsuboko Y, Miura H, Homma D
  • Journal Title: Int J Artif Organs Volume: 36(8) Pages: 575-575
  • Peer Reviewed
• [Journal Article] Transcutaneous communication system using the human body as conductive medium:Influence of transmission data current on the heart (2013)
  • Author(s): Eiji Okamoto, Sakiko Kikuchi, Hidekazu Miura, Yasuyuki Shiraishi, Tomoyuki Yambe, Yoshinori Mitamura
  • Journal Title: J.Bio-Medical Materials and Engineering Volume: 23(1-2) Issue: 1-2 Pages: 155-162
  • DOI: 10.3233/bme-120740
  • Peer Reviewed
• [Journal Article] Preliminary validation of a new magnetic wireless blood pump (2013)
  • Author(s): Kim SH, Ishiyama K, Hashi S, Shiraishi Y, Hayatsu Y, Akiyama M, Saiki Y, Yambe T
  • Journal Title: Artif Organs Volume: 37(10) Issue: 10 Pages: 920-6
  • DOI: 10.1111/aor.12093
  • Peer Reviewed
• [Journal Article] Improvement of a shape memory alloy fibered aortic pulsation device (2013)
  • Author(s): Hashem MO, Shiraishi Y, Yamada A, Tsuboko Y, Miura H, Yambe T, Homma D
  • Journal Title: IFMBE Proc Volume: 43 Pages: 399-402
  • Peer Reviewed
• [Journal Article] Modeling of signal transmissions in nerves in vitro for the development of a renal nerve cooling device for hypertension control (2013)
  • Author(s): Ito T, Shiraishi Y, Yambe T, et al.
  • Journal Title: IFMBE Proc Volume: 43 Pages: 448-451
  • DOI: 10.1007/978-3-319-02913-9_114
  • ISBN: 9783319029122, 9783319029139
  • Peer Reviewed
• [Journal Article] Preliminary study on contactless evaluation of peripheral perfusino during rotary blood pump support (2013)
  • Author(s): Sano K, Kitano T, Shiraishi Y, Yambe T, et al.
  • Journal Title: IFMBE Proc Volume: 43 Pages: 444-447
  • DOI: 10.1007/978-3-319-02913-9_113
  • ISBN: 9783319029122, 9783319029139
  • Peer Reviewed
• [Journal Article] Achievement of peristaltic design in the artificial esophagus based on esophageal characteristic analysis of goats' specimen (2013)
  • Author(s): Taira Y, Kamiya K, Shiraishi Y, Yambe T, et al.
  • Journal Title: IFMBE Proc Volume: 43 Pages: 372-374
  • DOI: 10.1007/978-3-319-02913-9_95
  • ISBN: 9783319029122, 9783319029139
  • Peer Reviewed
• [Presentation] 右心補助デバイス評価のための心房機能を再現した循環シミュレーションシステム開発 (2016)
  • Author(s): 坪子侑佑、武良盛太郎、白石泰之、池田純平、三浦英和、山田昭博、井上雄介、鈴木一郎、佐々木一益、鈴木拓志、平恭紀、山家智之
  • Organizer: 第44回人工心臓と補助循環懇話会学術集会
  • Place of Presentation: ホテル松島大観荘（宮城県・松島町）
  • Year and Date: 2016-03-04
• [Presentation] Fontan循環動物実験モデルによる拍動指標評価の試み (2016)
  • Author(s): 山田昭博、白石泰之、三浦英和、坪子侑佑、平恭紀、池田純平、井上雄介、山岸正明、本間大、山家智之
  • Organizer: 第44回人工心臓と補助循環懇話会学術集会
  • Place of Presentation: ホテル松島大観荘（宮城県・松島町）
  • Year and Date: 2016-03-04
• [Presentation] Fontan循環用呼吸時逆流抑制デバイス評価の試み (2016)
  • Author(s): 池田純平、白石泰之、山田昭博、坪子侑佑、平恭紀、鈴木拓志、井上雄介、本間大、山岸正明、山家智之
  • Organizer: 第44回人工心臓と補助循環懇話会学術集会
  • Place of Presentation: ホテル松島大観荘（宮城県・松島町）
  • Year and Date: 2016-03-04
• [Presentation] 循環デバイスの慢性実験評価 (2015)
  • Author(s): 白石泰之
  • Organizer: 日本生体医工学会医用アクチュエーション研究会
  • Place of Presentation: 産総研（東京）
  • Year and Date: 2015-11-27
  • Invited
• [Presentation] 右心模擬循環シミュレーションモデルによる小型右心用人工心筋の改良 (2015)
  • Author(s): 白石泰之、片平晋太郎、山田昭博、井上雄介、三浦英和、秋山正年、齋木佳克、山家智之、本間大
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 右心バイパス血流路を有する動物実験モデルによる小児用肺循環補助装置の血行動態評価 (2015)
  • Author(s): 山田昭博、白石泰之、山家智之、山岸正明、本間大
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] Fontan型手術の長期予後を改善する能動クリップ開発のための基礎検討 (2015)
  • Author(s): 池田純平、白石泰之、山田昭博、佐々木一益、本間大、山家智之、山岸正明
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 生体適合性の高い補助人工心臓用ハイブリッド脱血カニューレの開発 (2015)
  • Author(s): 井上 雄介, 川瀬 由季乃, 田代 彩夏, 磯山 隆, 斎藤 逸郎, 小野 俊哉, 原 伸太郎, 圦本 晃海, 李 欣陽, 村上 遥, 前野 映里奈, 三浦 英和, 白石 泰之, 山家 智之, 井街 宏, 阿部 裕輔
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 磁気伝導を用いた体内植え込み機器用非接触型システムの開発 (2015)
  • Author(s): 高地 健, 武良 盛太郎, 山田 昭博, 平 恭紀, 白石 泰之, 三浦 英和, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 逐次同定法を用いた補助人工心臓運用時の適応的拍動推定と心拍同期制御 (2015)
  • Author(s): 幡谷 原太, 田中 明, 吉澤 誠, 山家 智之, 白石 泰之, 三浦 英和
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] サポートベクタマシンを利用した補助人工心臓装着時の大動脈弁の開閉の有無及び開閉時間の推定 (2015)
  • Author(s): 鷹箸 修平, 田中 明, 吉澤 誠, 白石 泰之, 三浦 英和, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] CCDを用いた埋め込み型小型肺循環血流観察デバイス開発のための基礎検討 (2015)
  • Author(s): 渡辺 祥太, 白石 泰之, 三浦 英和, 井上 雄介, 山田 昭博, 坪子 侑佑, 平 恭紀, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 右心循環用に用いる人工心臓用モータの性能評価 (2015)
  • Author(s): 萩尾 勇樹, 三浦 英和, 白石 泰之, 片平 晋太郎, 佐々木 一益, 山田 昭博, 坪子 侑佑, 平 恭紀, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] 小児用ePTFE製肺動脈弁の弁葉およびbulging sinusが弁機能へ及ぼす影響の基礎検討 (2015)
  • Author(s): 坪子 侑佑, 白石 泰之, 武良 盛太郎, 山田 昭博, 山岸 正明, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] ePTFE製肺動脈弁の弁挙動解析の基礎検討 (2015)
  • Author(s): 武良 盛太郎, 白石 泰之, 坪子 侑佑, 三浦 英和, 山岸 正明, 山家 智之
  • Organizer: 第53回日本人工臓器学会大会
  • Place of Presentation: 東京ドームシティ（東京）
  • Year and Date: 2015-11-20
• [Presentation] Embedding quality into interaction between animal models and mechanical evaluation (2015)
  • Author(s): Shiraishi Y, Sasaki K, Yambe T, Saiki Y
  • Organizer: ICS2015
  • Place of Presentation: ゴールドコースト（オーストラリア）
  • Year and Date: 2015-11-14
  • Int'l Joint Research / Invited
• [Presentation] 形状記憶合金線維を用いた人工臓器に対する経皮的電力伝送システムの充電電流制御システムの構築 (2015)
  • Author(s): 三浦英和、山田昭博、Hashem MO, 白石泰之、佐藤文博、山家智之、松木英敏
  • Organizer: 第52回日本人工臓器学会大会
  • Place of Presentation: 札幌
  • Year and Date: 2015-10-19
• [Presentation] Hemodynamic assessment of an implantable shape memory alloy fibered aortic cardiovascular asssit device in animal model (2015)
  • Author(s): Hashem MO, Shiraish Y, Yambe T, Homma D
  • Organizer: 第52回日本人工臓器学会大会
  • Place of Presentation: 札幌
  • Year and Date: 2015-10-19
• [Presentation] A quantitative estimation method of peripheral perfusion by using a CCD camera during rotary blood pump support (2015)
  • Author(s): Shiraishi Y, Sano K, Watanabe S, Kitano T, Miura H, Tanaka A, Yoshizawa M, Yambe T.
  • Organizer: IUPSEM-World Congress 2015
  • Place of Presentation: トロント（カナダ）
  • Year and Date: 2015-06-11
• [Presentation] Contraction support for the right ventricle by a shape memory alloy fibered artificial myocardium (2015)
  • Author(s): Shiraishi Y, Yambe T.
  • Organizer: 10th Asian Control Conference
  • Place of Presentation: ステラリゾート（マレーシア）
  • Year and Date: 2015-06-01
  • Int'l Joint Research / Invited
• [Presentation] Non invasive evaluation of the renal blood flow during left ventricular assistance (2015)
  • Author(s): Shiraishi Y, Yambe T, Inoue Y, Sasaki K, Miura H, Tanaka A, Yoshizawa M, Katahira S, Akiyama M, Saiki Y
  • Organizer: 第54回日本生体医工学会大会
  • Place of Presentation: 名古屋国際会議場（名古屋）
  • Year and Date: 2015-05-07
• [Presentation] 埋込型小型右心人工心筋プロトタイプの開発設計 (2015)
  • Author(s): 白石泰之、片平晋太郎、秋山正年、早津幸弘、齋木佳克、山家智之、本間大
  • Organizer: 第43回人工心臓と補助循環懇話会学術集会
  • Place of Presentation: 熱海
  • Year and Date: 2015-02-21
• [Presentation] 形状記憶合金線維を応用した完全埋め込み型右心補助人工心臓開発設計 (2014)
  • Author(s): 白石泰之、片平晋太郎、金子芳一、山田昭博、秋山正年、齋木佳克、三浦英和、山家智之、本間大
  • Organizer: 第52回日本人工臓器学会大会
  • Place of Presentation: 札幌
  • Year and Date: 2014-10-19
• [Presentation] チタンメッシュを用いた経皮的情報通信用組織誘導電極のin vivo性能評価 (2014)
  • Author(s): 岡本英治、志田茜、三浦英和、白石泰之、山家智之、三田村好矩
  • Organizer: 第52回日本人工臓器学会大会
  • Place of Presentation: 札幌
  • Year and Date: 2014-10-19
• [Presentation] Building an artificial cardiovascular system (2014)
  • Author(s): Shiraishi Y, Yambe T
  • Organizer: Int Conf Smart Systems Engineering
  • Place of Presentation: Yonezawa
  • Year and Date: 2014-10-16
  • Invited
• [Presentation] ePTFE valve dynamics in the pulmonary mock circulatory system (2014)
  • Author(s): Shiraishi Y, Tsuboko Y, Yambe T, Qian Y
  • Organizer: Int Symposium on Advanced Fluid Information
  • Place of Presentation: Sendai
  • Year and Date: 2014-10-08
  • Invited
• [Presentation] Bioengineering desing of an artificial myocardial device using shape memory alloy fibers (2014)
  • Author(s): Shiraishi Y, Yamada A, Yambe T, Homma D
  • Organizer: Int Conf Materials and Processing
  • Place of Presentation: Detroit (USA)
  • Year and Date: 2014-07-12
  • Invited
• [Presentation] 東北大学における医療機器の動物実験評価 (2014)
  • Author(s): 白石泰之
  • Organizer: 第26回日本機械学会バイオエンジニアリング講演会
  • Place of Presentation: 仙台
  • Invited
• [Presentation] Engineering analysis for paediatric ePTFE valved conduit (2013)
  • Author(s): Shiraishi Y
  • Organizer: IEEE EMBS 2013
  • Place of Presentation: Osaka
  • Invited
• [Presentation] Combined assistance witrh an aortic external pulsation system and the centrifugal blood pump (2013)
  • Author(s): Shiraishi Y, Kitano T, Yambe T, et al.
  • Organizer: 21st Congress of ISRBP
  • Place of Presentation: Yokohama
• [Presentation] Hemodynamic Effect of an Atrial Contraction on Pulmonary Valve Functions in the Right Ventricular Simulator (2013)
  • Author(s): Tsuboko Y, Shiraishi Y, Yambe T, et al.
  • Organizer: 51st Annual Meeting of JSAO, 5th Congress of IFAO, 21st Congress of ISRBP
  • Place of Presentation: Yokohama
• [Presentation] Noninvasive and contactless examination of peripheral perfusion with different types of centrifugal blood pump support (2013)
  • Author(s): Sano K, Shiraishi Y, Yambe T, et al.
  • Organizer: 51st Annual Meeting of JSAO, 5th Congress of IFAO, 21st Congress of ISRBP
  • Place of Presentation: Yokohama
• [Presentation] Functional improvement of a newly developed extra aortic Counter-pulsation device using Shape Memory Alloy Fibers (2013)
  • Author(s): Hashem MO, Shiraishi Y, Yambe T, et al.
  • Organizer: 51st Annual Meeting of JSAO, 5th Congress of IFAO, 21st Congress of ISRBP
  • Place of Presentation: Yokohama
• [Presentation] Anisotropic structural design of an artificial esophagus based on pressure volume relation analysis of esophageal properties in goats (2013)
  • Author(s): Taira Y, Shiraishi Y, Yambe T, et al.
  • Organizer: 51st Annual Meeting of JSAO, 5th Congress of IFAO, 21st Congress of ISRBP
  • Place of Presentation: Yokohama
• [Book] 体内埋め込み医療材料の開発とその理想的な性能・デザインの要件 (2013)
  • Author(s): 佐藤章弘編、白石泰之ほか
  • Total Pages: 440
  • Publisher: 技術情報協会
• [Remarks] 東北大学加齢医学研究所心臓病電子医学分野
• [Remarks] 東北大学加齢医学研究所非臨床試験推進センター
• [Remarks] 東北大学加齢医学研究所心臓病電子医学分野
  • URL: http://mec1.idac.tohoku.ac.jp
• [Remarks] 東北大学加齢医学研究所心臓病電子医学分野
  • URL: http://mec1.idac.tohoku.ac.jp
• [Patent(Industrial Property Rights)] 医療用能動クリップ (2015)
  • Inventor(s): 白石泰之、山家智之、山岸正明
  • Industrial Property Rights Holder: 白石泰之、山家智之、山岸正明
  • Filing Date: 2015-03-20
• [Funded Workshop] 2nd Biomedical Symposium (2015)
  • Place of Presentation: Macquarie University Hospital（オーストラリア）
  • Year and Date: 2015-11-16