| Project/Area Number |
25282130
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KAMEDA Seiji 大阪大学, 国際医工情報センター, 特任准教授 (80542282)
SUEMATSU Naofumi 大阪大学, 大学院工学研究科, 准教授 (30779517)
TETSUYA Yagi 大阪大学, 大学院工学研究科, 教授 (50183976)
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| Research Collaborator |
YAMAKAWA Takahiro
IIZUKA Seita
SAKATA Yuya
OTA Rira
TANAKA Yuta
UMEHIRA Yuichi
NOMOTO Tomohiro
SUGA Shohei
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| Project Period (FY) |
2013-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Keywords | 生物・生体工学 / ナノ材料 / 脳・神経 / 神経電極 / 神経刺激 / 神経補綴 / 神経工学 / 神経生理学 |
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| Outline of Final Research Achievements |
We modified and improved our previously developed carbon-nanotube-bundle neural electrodes towards the implant application, and evaluated their performances in brain tissues by means of physiological experiments in vivo, and of others. As a result, we succeeded in fabricating CNTb electrodes having mechanical strength, shape, and electrochemical properties usable for insertion into, and the microstimulation in, the cerebral cortex of rodents in vivo. Furthermore, by millisecond resolution in-vivo imaging of the cortical activity, we demonstrated that the microstimulation through our CNTb electrodes can artificially induce neural excitations. We believe these unprecedented results will greatly expand the potential of neural prostheses with next-generation multi-channel stimulation.
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