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Developments of Plasma Soft X-ray Source for Microscopic Observation of Organelles in Living Cells with Focusing Capillary

Research Project

Project/Area Number 25282132
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionOsaka University

Principal Investigator

NAKANO Motohiro  大阪大学, 工学(系)研究科(研究院), 准教授 (40164256)

Co-Investigator(Kenkyū-buntansha) OSHIKANE Yasushi  大阪大学, 大学院工学研究科, 助教 (40263206)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Keywords放射線技術工学 / 水の窓軟X線顕微鏡 / プラズマ / キャピラリ / 放電生成プラズマ
Outline of Final Research Achievements

To create a future system of a table top "water window" soft X-ray microscope to observe organelles in living cells, we developed a small prototype light source system using focusing glass capillary, because glass has advantage of high reflectivity for wavelength region from 2.28 to 4.36 nm. The light intensity emitted from the discharge produced plasma assisted by pulsed laser, is measured with our small calibrated detector. In typical case of the discharge voltage 6kV with the single capillary, the electric discharge current is estimated approximately 6A with 0.01ms pulse, and the electric discharge energy is evaluated about 360mJ. However, the light intensity is not enough to observe organelles in living cells. We will reconstruct the "water window" soft X-ray source system using focusing polycapillary optics.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (2 results)

All 2015 2014

All Presentation (2 results)

  • [Presentation] 水の窓領域軟X線顕微鏡用レーザ生成プラズマ光源の開発 -集光による高輝度化に向けた反射膜の検討-2015

    • Author(s)
      星野広海,本郷優子,押鐘 寧,村井健介,中野元博
    • Organizer
      精密工学会2015年度関西地方定期学術講演会
    • Place of Presentation
      京都工芸繊維大学 (松ヶ崎キャンパス)
    • Year and Date
      2015-06-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] 水の窓領域軟X線顕微鏡用レーザ生成プラズマ光源の開発2014

    • Author(s)
      本郷優子、荻 佑介、押鐘 寧、中野元博
    • Organizer
      精密工学会2014年度関西地方定期学術講演会
    • Place of Presentation
      近畿大学 (東大阪キャンパス)
    • Year and Date
      2014-07-04
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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