Diffusion-tensor imaging for stroke outcome prediction: fractional anisotropy prediction models
| Project/Area Number |
25282168
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
Koyama Tetsuo 兵庫医科大学, 医学部, その他 (40538237)
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| Co-Investigator(Kenkyū-buntansha) |
道免 和久 兵庫医科大学, 医学部, 教授 (50207685)
内山 侑紀 兵庫医科大学, 医学部, 助教 (50725992)
足立 清香 兵庫医科大学, 医学部, 助教 (70731694)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2014: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2013: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Keywords | 脳卒中 / 予後予測 / 帰結 / 画像 / 核磁気共鳴画像 / 麻痺 / 画像診断 / 栄養管理 / 予後 / 予測 / 栄養 |
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| Outline of Final Research Achievements |
The relationships between fractional anisotropy (FA) of MRI diffusion-tensor imaging (DTI) and long-term outcome were assessed in patients after stroke. DTI data were obtained on days 14-18 and FA within the corticospinal tracts were calculated. Motor outcome of hemiparesis was evaluated using Brunnstrom stage (BRS) for separate shoulder/arm, hand, and lower extremity functions when patients were discharged from a long-term rehabilitation facility (2-7 months after onset). FIM-motor data were also scored. The ratio of FA in the affected hemisphere to those in the unaffected hemisphere (rFA) was assessed in relation to BRS and FIM-motor data. Analysis revealed tight relationships between rFA and upper extremity function (R, 0.63-0.78) and moderate relationships between rFA and lower extremity function (R, 0.59-0.63). The relationships between rFA and FIM-motor were less evident (R, 0.28-0.44). DTI-FA values may be useful for the prediction of long-term outcomes of stroke patients.
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Report
(4 results)
Research Products
(13 results)
