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Development of muscle functional MRI (mfMRI) using new parameter for clarification of muscle activity that induced exercise

Research Project

Project/Area Number 25282170
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionJapan Health Care College (2016)
Hokkaido University (2014-2015)
National Agency for the Advancement of Sports and Health (2013)

Principal Investigator

Tawara Noriyuki  日本医療大学, 保健医療学部, 教授 (30344279)

Research Collaborator Anchali Krisanachinda  Chulalongkorn University, Faculty of Medicine, Associate Professor
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2013: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords骨格筋 / 横緩和時間(T2) / 縦緩和時間(T1) / 運動 / SE-EPI / DESS / TurboFLASH / Goodness-of-fit / Goodness-of-Fit Measure / 回帰分析 / MRI / 緩和時間 / mfMRI / 運動負荷 / T2値 / 筋機能的MRI
Outline of Final Research Achievements

For sport and rehabilitation medicine, the quantitative evaluation of exercised muscle activity is essential for facilitating optimal exercise selection and designing effective exercise programs. Magnetic resonance imaging (MRI) allows the simultaneous noninvasive investigation of superficial and deep muscle activity during exercise. However, there are many problems to be solved in order to utilize mfMRI. The purpose of this study was to investigate the new techniques of muscle functional MRI (mfMRI) in order to evaluate the human muscle activity that induced exercise.
As the results, this research revealed the basis of the acquiring condition to reduce scanning time for calculating the transverse relaxation time (T2) of skeletal muscle. We showed the muscle activity of abdominal oblique muscles by mfMRI. In addition, we could also propose a method to reduce the scanning time for calculating longitudinal relaxation time (T1) of skeletal muscle using general pulse sequence.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (19 results)

All 2017 2016 2015 2014 2013 Other

All Int'l Joint Research (2 results) Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (15 results) (of which Int'l Joint Research: 6 results) Remarks (1 results)

  • [Int'l Joint Research] Chulalongkorn University(Thailand)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Chulalongkorn University(Thailand)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Effect of number of measurement points on accuracy of muscle T2 calculations.2016

    • Author(s)
      Tawara N, Nishiyama A.
    • Journal Title

      Investig Magn Reson Imaging

      Volume: 20(4) Issue: 4 Pages: 207-214

    • DOI

      10.13104/imri.2016.20.4.207

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] A Comparison between Single-Shot SE-EPI and Multi-Shot SE-EPI on Calculating T2.2017

    • Author(s)
      Tawara N, Nishiyama A.
    • Organizer
      ICMRI2017, 2017.03.24, Seoul
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2017-03-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of repetition time during the measurement of muscle T2 for investigating muscle activity at 1.5 tesla MRI, ICMP2016, 2016.12.10, Bamgkok2016

    • Author(s)
      Polharn P, Krisanachinda A, Tawara N, Ponkanist K.
    • Organizer
      ICMP2016
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2016-12-09
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rapid T1 measurement using Fast imaging.2016

    • Author(s)
      Tawara N, Atsushi Nishiyama A.
    • Organizer
      第44回日本磁気共鳴医学会大会
    • Place of Presentation
      さいたま市, 埼玉県
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] Accuracy evaluation of pulse sequences using inversion recovery pulse for T1 measurement.2016

    • Author(s)
      Tawara N, Ponkanist K, Shiratori S, Krisanachinda A, Yamamoto T. Accuracy evaluation of pulse sequences using inversion recovery pulse for T1 measurement. 23th ISMRM, 2016.05.12, Suntec City
    • Organizer
      23th ISMRM, 2016.05.12, Suntec City
    • Place of Presentation
      Suntec City, Singapore
    • Year and Date
      2016-05-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Accuracy evaluation of pulse sequences using inversion recovery pulse for T1 measurement.2016

    • Author(s)
      Noriyuki Tawara, Kanokvalee Ponkanist, Shuichi Shiratori, Anchali Krisanachinda, and Toru Yamamoto
    • Organizer
      24th Annual meeting and Exhibition of International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Suntec City (Singapore)
    • Year and Date
      2016-05-07
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Complications related to the number of measurement point during the measurement of muscle T2: flip angles for calculation of muscle T2. In: Proceedings of the 21th Annual Scientific Meeting of Korea Society for Magnetic Resonance in Medicine (KSMRM), Seoul, Korea, 2016; p---(SS06-2). (2016.03.26)2016

    • Author(s)
      Noriyuki Tawara
    • Organizer
      the 21th Annual Scientific Meeting of Korea Society for Magnetic Resonance in Medicine (KSMRM), Seoul, Korea, 2016; p---(SS06-2). (2016.03.26)
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2016-03-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dynamic analysis of T2 and proton density of exercise-induced muscle using SE-EPI2015

    • Author(s)
      Tawara N, Yamamoto T.
    • Organizer
      the 23rd Annual Scientific Meeting of International Society for Magnetic Resonance in Medicine (ISMRM)
    • Place of Presentation
      Tronto, Canada
    • Year and Date
      2015-06-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dynamic analysis of T2 and proton density of exercise-induced muscle using SE-EPI2015

    • Author(s)
      Noriyuki Tawara, Takahiro Ohnishi, Toru Yamamoto
    • Organizer
      23th Annual meeting and Exhibition of International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Toronto (Canada)
    • Year and Date
      2015-05-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Muscle functional MRI using Thee-dimensional double-echo steady-state (3D-DESS) sequence at 3.0T: flip angles for calculation of muscle T2.2015

    • Author(s)
      Tawara N, Washiyama E.
    • Organizer
      the 20th Annual Scientific Meeting of Korea Society for Magnetic Resonance in Medicine (KSMRM)
    • Place of Presentation
      Seoul, Koria
    • Year and Date
      2015-03-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 筋機能的MRIを用いた運動に誘発された体幹部腹斜筋の筋活動検出の試み2014

    • Author(s)
      俵紀行,大西貴弘,新津守
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Changes of transverse relaxation time (T2) of the exercised skeletal muscle by ultrafast imaging2014

    • Author(s)
      Noriyuki Tawara, Eiji Washiyama, Takahiro Ohnishi, Mamoru Niitsu, Kohei Nakajima, Toru Okuwaki, Takashi Kawahara
    • Organizer
      European Congress of Radiology (ECR)
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2013 Annual Research Report
  • [Presentation] Inversion recovery pulse effect on muscle T2 calculation2014

    • Author(s)
      Noriyuki Tawara, Eiji Washiyama, Takahiro Ohnishi, Mamoru Niitsu, Kohei Nakajima, Toru Okuwaki, Takashi Kawahara
    • Organizer
      the 19th Annual Scientific Meeting of Korea Society for Magnetic Resonance in Medicine (KSMRM)
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Detectability of exercise-induced muscle activities of abdominal oblique muscle using muscle functional MRI2013

    • Author(s)
      Noriyuki Tawara, Takahiro Ohnishi, Katsuya Maruyama, Vladimir Jellus, Naoyuki Tamura, Hideyuki Takahashi, Mamoru Niitsu, Atsuto Hoshikawa, Kohei Nakajima, Toru Okuwaki, Takashi Kawahara
    • Organizer
      the 21th Annual meeting and Exhibition of International Society for Magnetic Resonance in Medicine (ISMRM)
    • Place of Presentation
      Solt Lake City, Utah, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 3.0T-MRI装置を用いた骨格筋T2算出における高速撮像法の活用に関する比較評価2013

    • Author(s)
      俵紀行,大西貴弘,丸山克也,新津守,川原貴
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      徳島
    • Related Report
      2013 Annual Research Report
  • [Presentation] 3.0T-MRI装置における骨格筋T2計測に影響を及ぼす繰返時間に関する検討2013

    • Author(s)
      俵紀行,川原貴
    • Organizer
      日本放射線技術学会第41回秋季学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Annual Research Report
  • [Remarks] 日本医療大学保健医療学部診療放射線学科教員紹介/俵紀行

    • URL

      http://www.nihoniryo-c.ac.jp/radiological-sciences/teaching-staff/noriyuki-tawara/

    • Related Report
      2016 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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