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Basic and clinical research for the mechanism of increasing blood flow in the pelvic organs during neuro-bionics.

Research Project

Project/Area Number 25282171
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTohoku University

Principal Investigator

NAKAGAWA HARUO  東北大学, 医学(系)研究科(研究院), 非常勤講師 (80333574)

Co-Investigator(Kenkyū-buntansha) 山下 慎一  東北大学, 大学病院, 助教 (10622425)
海法 康裕  東北大学, 大学病院, 講師 (30447130)
荒井 陽一  東北大学, 医学(系)研究科(研究院), 教授 (50193058)
川守田 直樹  東北大学, 医学(系)研究科(研究院), 助教 (00617524)
泉 秀明  東北大学, 大学病院, 助教 (80722545)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Keywordsニューロバイオニクス / 血流 / 作用機序 / 加齢 / 排尿障害
Outline of Final Research Achievements

We evaluated the blood flow during neuro-bionics. In the mice, pelvic organ's blood flow promptly increases after electrical stimulation. Increasing blood flow was clearly observed in urinary bladder, prostate and penis. This result suggests that one of the mechanisms of neuro-bionics is improvement of ischemia of pelvic organ. An evoked magnetic field during neuro-bionics was observed with magnetoencephalography. In this magnetoencephalography study, single dipole was calculated near the primary sensory area in the brain. This result suggests that one of the mechanisms of neuro-bionics concerns central nerve system.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (15 results)

All 2016 2015 2014 Other

All Presentation (14 results) (of which Int'l Joint Research: 3 results,  Invited: 10 results) Book (1 results)

  • [Presentation] 夜間頻尿診療のパラダイムシフト 「夜間頻尿の疫学調査・病態の総論」2016

    • Author(s)
      中川晴夫
    • Organizer
      泌尿器科学会東部総会
    • Place of Presentation
      ホテル青森(青森県・青森市)
    • Year and Date
      2016-10-09
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高齢者過活動膀胱の治療のポイント2016

    • Author(s)
      中川晴夫
    • Organizer
      第29回老年泌尿器科学会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-05-13
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高齢者過活動膀胱のケアと治療2016

    • Author(s)
      中川晴夫
    • Organizer
      第29回日本老年泌尿器科学会
    • Place of Presentation
      福岡市 福岡国際会議場
    • Year and Date
      2016-05-13
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Crucial roles of nitric oxide synthases in β-adrenoceptor-mediated bladder relaxation in mice2016

    • Author(s)
      Satake Y, Kaiho Y, Satoh K, Yamashita S, Tsutsui M, Shimokawa H, Arai Y
    • Organizer
      31st Annual Congress of the European Association of Urology
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2016-03-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of sacral neuromodulation on pelvic hemodynamics2015

    • Author(s)
      Kamiyama Y, Yamashita S, Izumi H, Satake Y, Eriguchi T, Kawamorita N, Kaiho Y, Ito A, Nakagawa H, Arai Y
    • Organizer
      International Continence Society 43rd Annual Meeting
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2015-10-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of sacral neuromodulation on pelvic hemodynamics2015

    • Author(s)
      Kamiyama Y, Yamashita S, Fujii S, Eriguchi T, Satake Y, Izumi H, Kawamorita N, Kaiho Y, Nakagawa H, Arai Y
    • Organizer
      32nd Korea-Japan Urological Congress
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 仙骨部表面電気刺激の骨盤内血流への影響の検討2015

    • Author(s)
      神山佳展, 山下慎一, 藤井紳司、江里口智大, 佐竹洋平, 泉秀明, 川守田直樹, 海法康裕, 中川晴夫, 荒井陽一
    • Organizer
      第22回日本排尿機能学会
    • Place of Presentation
      札幌市 京王プラザホテル
    • Year and Date
      2015-09-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 夜間頻尿の背景と治療~新たなエビデンスを踏まえて~2015

    • Author(s)
      中川晴夫
    • Organizer
      第103回日本泌尿器科学会
    • Place of Presentation
      金沢市 アートホール
    • Year and Date
      2015-04-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 夜間頻尿の背景と治療~新たなエビデンスを踏まえて~2015

    • Author(s)
      中川晴夫
    • Organizer
      第103回日本泌尿器科学会総会
    • Place of Presentation
      金沢市(金沢市アートホール)
    • Year and Date
      2015-04-19
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 夜間頻尿の要因と対処2014

    • Author(s)
      中川晴夫
    • Organizer
      第102回日本泌尿器科学会総会
    • Place of Presentation
      神戸市(神戸国際会議場)
    • Year and Date
      2014-04-25
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 過活動膀胱と夜間頻尿~その原因と対策~

    • Author(s)
      中川晴夫
    • Organizer
      第78回日本泌尿器科学会東部総会
    • Place of Presentation
      新潟市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] シンポジウム:中枢神経と排尿障害~最新の話題 「脳磁図を利用した仙骨表面治療的電気刺激療法の刺激条件設定」

    • Author(s)
      中川晴夫、海法康裕、荒井陽一
    • Organizer
      第66回日本自律神経学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] シンポジウム:排泄ケア-問題点と進歩 「排尿障害に対する新しい治療」

    • Author(s)
      中川晴夫
    • Organizer
      第31回日本ストーマ・排泄リハビリテーション学会
    • Place of Presentation
      仙台市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 夜間頻尿の要因と対処

    • Author(s)
      中川晴夫
    • Organizer
      第102回日本泌尿器科学会総会
    • Place of Presentation
      神戸市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] Clinical Benefit of LUTS Treatment2015

    • Author(s)
      Haruo Nakagawa, Krisitam V. Juul
    • Total Pages
      183
    • Publisher
      ELSEVIER
    • Related Report
      2015 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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