Diffuse optical tomography meeting probablistic registration

• Project/Area Number: 25282243
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Basic / Social brain science
• Research Institution: Chuo University
• Principal Investigator: Dan Ippeita 中央大学, 理工学部, 教授 (20399380)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000); Fiscal Year 2015: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000); Fiscal Year 2014: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000); Fiscal Year 2013: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
• Keywords: fNIRS / 拡散光イメージング / 脳機能イメージング / 標準脳座標系 / 解剖学的構造

Outline of Final Research Achievements

In the past two decades, two-dimensional version of fNIRS has acquired various applications, and has developed to be a three-dimensional imaging technique called diffuse optical tomography (DOT), in which illuminator-detector pairs were formed at various distances in an overlapping ways to reconstruct depth-resolved image. Prerequisite for high-resolution image of DOT is the corresponding subject-specific image of brain and head tissue structures, which are not always available. Thus, we developed the probabilistic version of the atlas-guided DOT and examine its feasibility as an MRI-free approach to anatomically guided DOT image reconstruction. The cost of not using subjects’ own MRIs was reasonablly small. Moreover, we adopted a new method referring to Eigen values to effectively control multiplicity in multi-channel fNIRS using effective multiplicity derived from the eigenvalues of correlation matrices, with Meff being controlled at 10 to 15 in a 44-channel setting.

Research Products

• [Int'l Joint Research] University College London(英国)
• [Int'l Joint Research] Harvard Medical School(米国)
• [Journal Article] MinR 10/20 system: Quantitative and reproducible cranial landmark setting method for MRI based on minimum initial reference points (2016)
  • Author(s): Tsuzuki, D., Watanabe, H., Dan, I. & Taga, G.
  • Journal Title: Journal of Neuroscience Methods Volume: 264 Pages: 86-93
  • DOI: 10.1016/j.jneumeth.2016.02.024
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Sensor space group analysis for fNIRS data (2016)
  • Author(s): Tak, S., Uga, M., Flandin, G., Dan, I., and Penny, W. D.
  • Journal Title: Journal of Neuroscience Methods Volume: 263 Pages: 103-112
  • DOI: 10.1016/j.jneumeth.2016.03.003
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Individual classification of ADHD children by right prefrontal hemodynamic responses during a go/no-go task as assessed by fNIRS. (2015)
  • Author(s): Monden Y, Dan I, Nagashima M, Dan H, Uga M, Ikeda T, Tsuzuki D, Kyutoku Y, Gunji Y, Hirano D, Taniguchi T, Shimoizumi H, Watanabe E, Yamagata T.
  • Journal Title: NeuroImage Clinical Volume: 9 Pages: 1-12
  • DOI: 10.1016/j.nicl.2015.06.011
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The association between aerobic fitness and cognitive function in older men mediated by frontal lateralization. (2015)
  • Author(s): Hyodo K, Dan I, Kyutoku Y, Suwabe K, Byun K, Ochi G, Kato M, Soya H
  • Journal Title: Neuroimage Volume: 125 Pages: 291-300
  • DOI: 10.1016/j.neuroimage.2015.09.062
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Exploring effective multiplicity in multichannel functional near-infrared spectroscopy using eigenvalues of correlation matrices. (2015)
  • Author(s): Minako Uga, Ippeita Dan, Haruka Dan, Yasushi Kyutoku, Y-h Taguchi, Eiju Watanabe
  • Journal Title: Neurophotonics Volume: 2 Issue: 1 Pages: 015002-015002
  • DOI: 10.1117/1.nph.2.1.015002
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial (2015)
  • Author(s): Aasted, C.M., Yücel, M.A., Cooper, R.J., Dubb, J., Tsuzuki, D., Becerra, L., Petkov, M. P., Borsook, D., Dan, I., and Boas, D. A.
  • Journal Title: Neurophotonics Volume: 2 Issue: 2 Pages: 020801-020801
  • DOI: 10.1117/1.nph.2.2.020801
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Determination of epileptic focus side in mesial temporal lobe epilepsy using long-term noninvasive fNIRS/EEG monitoring for presurgical evaluation. (2015)
  • Author(s): Rizki,EE, Uga M, Dan I, Dan H, Tsuzuki D, Yokota H, Oguro K, Watanabe E
  • Journal Title: Neurophotonics Volume: 2 Issue: 2 Pages: 0250031-13
  • DOI: 10.1117/1.nph.2.2.025003
  • Peer Reviewed / Open Access
• [Journal Article] Acute neuropharmacological effects of atomoxetine on inhibitory control in ADHD children: an fNIRS study (2014)
  • Author(s): Nagashima M, Monden Y*,Dan I, Dan H, Tsuzuki D, Tsuzuki D, Mizutani T, Kyutoku Y, Gunji Y, Hirano D, Taniguchi T, Shimoizumi H, Momoi MY, Watanabe E, and Yamagata T,
  • Journal Title: NeuroImage:Clinical Volume: 6 Pages: 192-201
  • DOI: 10.1016/j.nicl.2014.09.001
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Neuropharmacological effect of atomoxetine on attention network in children with attention deficit hyperactivity disorder during oddball paradigms as assessed using functional near-infrared spectroscopy (2014)
  • Author(s): Masako Nagashima, Yukifumi Monden, Ippeita Dan, Haruka Dan, Tsutomu Mizutani, Daisuke Tsuzuki, Yasushi Kyutoku, Yuji Gunji, Daisuke Hirano, Takamichi Taniguchi, Hideo Shimoizumi, Mariko Y. Momoi, Takanori Yamagata, Eiju Watanabe
  • Journal Title: Neurophotonics Volume: 1 Issue: 2 Pages: 0250071-14
  • DOI: 10.1117/1.nph.1.2.025007
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Referential framework for transcranial anatomical correspondence for fNIRS based on manually traced sulci and gyri of an infant brain (2014)
  • Author(s): Matsui M, Homae F, Tsuzuki D, Watanabe H, Katagiri M, Uda S, Nakashima M, Dan I, Taga G
  • Journal Title: Neuroscience Research Volume: 印刷中 Pages: 55-68
  • DOI: 10.1016/j.neures.2014.01.003
  • Peer Reviewed
• [Journal Article] Positive effect of acute mild exercise on executive function via arousal-related prefrontal activations (2014)
  • Author(s): Byun K, Hyodo K, Suwabe K, Ochi G, Sakairi Y, Kato M, Dan I, Soya H
  • Journal Title: Neuroimage Volume: 98 Pages: 336-345
  • DOI: 10.1016/j.neuroimage.2014.04.067
  • Peer Reviewed
• [Journal Article] Neuropharmacological effect of methylphenidate on attention network in children with attention deficit/hyperactivity disorder during oddball paradigms as assessed using fNIRS (2014)
  • Author(s): Nagashima M, Dan I, Monden Y, Dan H, Tsuzuki D, Mizutani T, Kyutoku Y, Gunji Y, Momoi MY, Watanabe W, Yamagata T
  • Journal Title: Neurophotonics Volume: in press
  • Peer Reviewed
• [Presentation] Age-related cortical representation for acute neuropharmacological effects of atomoxetine and methylphenidate on children with attention deficit/hyperactivity disorder as assessed using fNIRS (2015)
  • Author(s): Dan, I.
  • Organizer: Neuro 2015
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2015-07-28
  • Int'l Joint Research / Invited
• [Presentation] Acute neuropharmacological effects of atomoxetine and methylphenidate on children with attention deficit/hyperactivity disorder as assessed using fNIRS (2014)
  • Author(s): Dan, I., Nagashima, M., Monden, Y., Dan, H., Mizutani, T., Tsuzuki, D., Kyutoku, Y., Gunji, Y., Hirano, D., Taniguchi, T., Shimoizumi, H., Momoi, M.Y., Watanabe, E., & Yamagata, T.
  • Organizer: fNIRS 2014
  • Place of Presentation: Montreal, Canada
  • Year and Date: 2014-10-10
  • Int'l Joint Research
• [Remarks] 身体の持久力を保つことは脳の老化を防ぐ！：プレスリリース
  • URL: http://brain-lab.jp/wp/?p=1496
• [Remarks] 個人レベルの脳機能検査でADHD症状の可視化に成功：プレスリリース
  • URL: http://brain-lab.jp/wp/?p=1286
• [Remarks] ADHD治療薬効果判定と光トポグラフィー：プレスリリース資料
  • URL: http://brain-lab.jp/wp/?p=1040
• [Remarks] Dan's Lab at Chuo University
  • URL: http://brain-lab.jp/
• [Remarks] ダイレクト光トポグラフィー：プレスリリース資料
  • URL: http://brain-lab.jp/wp/?p=775