Research on memory retrieval mechanisms in the primate medial temporal lobe using high-density electrocorticography

• Project/Area Number: 25282249
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Brain biometrics
• Research Institution: Kochi University of Technology
• Principal Investigator: Kiyoshi Nakahara 高知工科大学, 総合研究所, 教授 (50372363)
• Co-Investigator(Kenkyū-buntansha): 川嵜 圭祐 新潟大学, 医歯学系, 准教授 (60511178)
• Co-Investigator(Renkei-kenkyūsha): SAWAHATA Hirohito 豊橋技術科学大学, 電気・電子情報工学系, 特任助教 (40571774)
• Research Collaborator: ADACHI Ken
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000); Fiscal Year 2015: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2014: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2013: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
• Keywords: 連合記憶 / 皮質脳波 / 内側側頭葉 / 霊長類 / 長期記憶 / 側頭葉 / シータ波 / 空間パターン / 記憶

Outline of Final Research Achievements

Using high-density electrocorticography (ECoG), we investigated local-field potentials spanning the monkey temporal lobes, and found that the visual pair-association memory is encoded in spatial patterns of theta activity in the primate medial temporal lobe.

Research Products

• [Journal Article] Associative-memory representations emerge as shared spatial patterns of theta activity spanning the primate temporal cortex (2016)
  • Author(s): Kiyoshi Nakahara, Ken Adachi, Keisuke Kawasaki, Takeshi Matsuo, Hirohito Sawahata, Kei Majima, Masaki Takeda, Sayaka Sugiyama, Ryota Nakata, Atsuhiko Iijima, Hisashi Tanigawa, Takafumi Suzuki, Yukiyasu Kamitani, Isao Hasegawa
  • Journal Title: Nature Communications Volume: 未定 Issue: 1 Pages: 11827-11827
  • DOI: 10.1038/ncomms11827
  • NAID: 120005822769
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Cross-frequency coupling of cortical oscillations during long-term memory retrieval in the monkey medial temporal lobe. (2014)
  • Author(s): 1.Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Tanigawa H., Iijima A., Hasegawa I. and Nakahara K.
  • Organizer: Neuroscience 2014
  • Place of Presentation: Washington DC, USA
  • Year and Date: 2014-11-16
• [Presentation] Spatial pattern similarity of ECoG responses represents associative memory in the primate medial temporal lobe. (2014)
  • Author(s): 1.Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Majima K., Tanigawa H., Iijima A., Kamitani Y., Hasegawa I. and Nakahara K.
  • Organizer: 第37回日本神経科学大会
  • Place of Presentation: 横浜
  • Year and Date: 2014-09-13
• [Presentation] Decoding from ECoG signals reveals the contents of color imagery in macaque inferior temporal and prefrontal cortices. (2014)
  • Author(s): 2.Takei R., Tanigawa H., Majima K., Kawasaki K., Sawahata H., Nakahara K., Iijima A., Suzuki T., Kamitani Y. and Hasegawa I.
  • Organizer: 第37回日本神経科学大会
  • Place of Presentation: 横浜
  • Year and Date: 2014-09-13
• [Presentation] Cortical theta waves associated with a visual long-term memory task in the monkey medial temporal lobe.
  • Author(s): 1. Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Tanigawa H., Iijima A., Hasegawa I. and Nakahara K.
  • Organizer: Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, USA
• [Presentation] Cross-frequency coupling of cortical oscillations during long-term memory retrieval in the monkey medial temporal lobe.
  • Author(s): 4. Adachi K., Kawasaki K., Sawahata H., Matsuo T., Suzuki T., Tanigawa H., Iijima A., Hasegawa I. and Nakahara K.
  • Organizer: 第３６回日本神経科学大会
  • Place of Presentation: Kyoto, Japan