Development of a fotonic microfluidic device for single cell analysis
| Project/Area Number |
25286034
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nano/Microsystems
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ASAKAWA KIYOSHI 筑波大学, 数理物質系, 客員教授 (20375405)
SUGIMOTO YOSHIMASA 独立行政法人物質・材料研究機構, 先端的共通技術部門, 主席研究員 (60415784)
OZAKI NOBUHIKO 和歌山大学, システム工学部, 准教授 (30344873)
YOKOKAWA MASATOSHI 筑波大学, 数理物質系, 助教 (50447885)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2013: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Keywords | 細胞 / 光方向性結合器 / 導波路 / ポリマー / 窒化シリコン / バイオセンサ / 方向性結合器 / バイオセンシング / 微小流路 / 屈折率 / DNA / 単一細胞解析 / 方向性結合器干渉計 / マルチモード型干渉計 / サイトカイン / 抗体 |
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| Outline of Final Research Achievements |
To detect molecules secreted from animal cells, an optical directional coupler (DC) was used to realize a micro biosensing system. First, the DC was fabricated with polymer waveguides and the function was confirmed. Then, a silicon nitride DC was fabricated. Simulation was conducted to design these devices and the performance of the devices was characterized. The device was coupled with a microfluidic system and sensing of biomolecules was conducted there.
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Report
(4 results)
Research Products
(10 results)
