Cooperative Effect of Multi-Active Sites in Catalytic Reactions
| Project/Area Number |
25288019
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo University of Science (2015)
Kanazawa University |
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Principal Investigator |
Endo Kohei 東京理科大学, 理学部, 准教授 (70454064)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 分子触媒 / 有機金属化学 / クラスター / 有機化学 / 多核金属錯体触媒 / 金属クラスター触媒 / 超分子化学 / 触媒反応 / 立体選択的 / 有機金属錯体 / 元素戦略 |
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| Outline of Final Research Achievements |
The present project for the development of multi-active sites in catalysis revealed the electrophilic activation by neighboring atoms for the activation of a reactive site. (1) The use of Fischer-type carbene complexes as electrophilic organometallic intermediates realized the tandem nucleophilic addition reaction. The use of stable cyclopropenes as carbene precursors provides a allylmetal intermediates via the reaction with organometallic reagents, followed by the tandem allylation reaction of appropriate electrophiles took place efficiently. (2) The multi-metallic catalysts achieved the asymmetric conjugate addition to give chiral furnaces bearing a quaternary stereogenic center. (3) The bimetallic cluster system showed unique chemo- and stereoselectivity in the reduction of alkynes using formic acid.
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Report
(4 results)
Research Products
(20 results)
